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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    36401 1olp:D (2.5) BS04 ZN 3.1.4.3 GO:0004629 ... Q8GCY3 14568535
    36402 1olp:D (2.5) BS05 ZN 3.1.4.3 GO:0004629 ... Q8GCY3 14568535
    36403 1ols:A (1.85) BS01 MN 1.2.4.4 GO:0003863 ... P12694 12902323
    36404 1ols:A (1.85) BS02 TPP 1.2.4.4 GO:0003863 ... P12694 12902323
    36405 1olt:A (2.07) BS01 SF4 1.3.98.3 GO:0003824 ... P32131 14633981
    36406 1olt:A (2.07) BS02 SAM 1.3.98.3 GO:0003824 ... P32131 14633981
    36407 1olt:A (2.07) BS03 SAM 1.3.98.3 GO:0003824 ... P32131 14633981
    36408 1olu:A (1.9) BS01 MG 1.2.4.4 GO:0003863 ... P12694 12902323
    36409 1olu:A (1.9) BS02 TPP 1.2.4.4 GO:0003863 ... P12694 12902323
    36410 1olx:A (2.25) BS01 MN 1.2.4.4 GO:0003863 ... P12694 12902323
    36411 1olx:A (2.25) BS02 TPP 1.2.4.4 GO:0003863 ... P12694 12902323
    36412 1om1:A (1.68) BS01 IQA 2.7.11.1 GO:0004672 ... P28523 12816539 MOAD: Ki=0.17uM
    PDBbind: -logKd/Ki=6.77, Ki=0.17uM
    36413 1om2:A (-1.00) BS01 peptide ? GO:0005742 ... Q62760 10721992
    36414 1om4:A (1.75) BS01 ZN 1.14.13.39 GO:0004517 ... P29476 N/A
    36415 1om4:A (1.75) BS02 HEM 1.14.13.39 GO:0004517 ... P29476 N/A
    36416 1om4:A (1.75) BS03 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36417 1om4:A (1.75) BS04 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36418 1om4:A (1.75) BS05 ARG 1.14.13.39 GO:0004517 ... P29476 N/A
    36419 1om4:B (1.75) BS01 ZN 1.14.13.39 GO:0004517 ... P29476 N/A
    36420 1om4:B (1.75) BS02 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36421 1om4:B (1.75) BS03 HEM 1.14.13.39 GO:0004517 ... P29476 N/A
    36422 1om4:B (1.75) BS04 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36423 1om4:B (1.75) BS05 ARG 1.14.13.39 GO:0004517 ... P29476 N/A
    36424 1om5:A (2.3) BS01 ZN 1.14.13.39 GO:0004517 ... P29476 N/A
    36425 1om5:A (2.3) BS02 HEM 1.14.13.39 GO:0004517 ... P29476 N/A
    36426 1om5:A (2.3) BS03 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36427 1om5:A (2.3) BS04 INE 1.14.13.39 GO:0004517 ... P29476 N/A BindingDB: IC50=1800nM
    36428 1om5:A (2.3) BS05 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36429 1om5:B (2.3) BS01 ZN 1.14.13.39 GO:0004517 ... P29476 N/A
    36430 1om5:B (2.3) BS02 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36431 1om5:B (2.3) BS03 HEM 1.14.13.39 GO:0004517 ... P29476 N/A
    36432 1om5:B (2.3) BS04 H4B 1.14.13.39 GO:0004517 ... P29476 N/A
    36433 1om5:B (2.3) BS05 INE 1.14.13.39 GO:0004517 ... P29476 N/A BindingDB: IC50=1800nM
    36434 1om6:A (2.0) BS01 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36435 1om6:A (2.0) BS02 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36436 1om6:A (2.0) BS03 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36437 1om6:A (2.0) BS04 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36438 1om6:A (2.0) BS05 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36439 1om6:A (2.0) BS06 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36440 1om7:A (2.8) BS01 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36441 1om7:A (2.8) BS02 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36442 1om7:A (2.8) BS03 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36443 1om7:A (2.8) BS04 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36444 1om7:A (2.8) BS05 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36445 1om8:A (2.0) BS01 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36446 1om8:A (2.0) BS02 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36447 1om8:A (2.0) BS03 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36448 1om8:A (2.0) BS04 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36449 1om8:A (2.0) BS05 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36450 1om8:A (2.0) BS06 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36451 1om9:A (2.5) BS01 peptide ? GO:0005802 ... Q9UJY5 12858163
    36452 1om9:B (2.5) BS01 peptide ? GO:0005802 ... Q9UJY5 12858163
    36453 1omd:A (1.85) BS01 CA ? GO:0005509 ... P02631 2231727
    36454 1omd:A (1.85) BS02 CA ? GO:0005509 ... P02631 2231727
    36455 1omd:A (1.85) BS03 CA ? GO:0005509 ... P02631 2231727
    36456 1omj:A (2.38) BS01 ZN 3.4.24.40 GO:0004222 ... O69771 12837794
    36457 1omj:A (2.38) BS02 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36458 1omj:A (2.38) BS03 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36459 1omj:A (2.38) BS04 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36460 1omj:A (2.38) BS05 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36461 1omj:A (2.38) BS06 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36462 1omj:A (2.38) BS07 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36463 1omj:A (2.38) BS08 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36464 1omj:A (2.38) BS09 CA 3.4.24.40 GO:0004222 ... O69771 12837794
    36465 1omo:A (2.32) BS01 NAD 1.4.1.1 GO:0000166 ... O28608 15313611
    36466 1omo:B (2.32) BS01 NAD 1.4.1.1 GO:0000166 ... O28608 15313611
    36467 1omr:A (1.5) BS01 CA ? GO:0001750 ... P21457 12686556
    36468 1omv:A (1.9) BS01 CA ? GO:0001750 ... P21457 12686556
    36469 1omz:A (2.1) BS01 UD2 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36470 1omz:B (2.1) BS01 UD2 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36471 1on1:A (1.75) BS01 MN ? GO:0003677 ... P54512 12847518
    36472 1on1:A (1.75) BS02 MN ? GO:0003677 ... P54512 12847518
    36473 1on1:B (1.75) BS01 MN ? GO:0003677 ... P54512 12847518
    36474 1on1:B (1.75) BS02 MN ? GO:0003677 ... P54512 12847518
    36475 1on2:A (1.61) BS01 MN ? GO:0003677 ... P54512 12847518
    36476 1on2:B (1.61) BS01 MN ? GO:0003677 ... P54512 12847518
    36477 1on3:A (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36478 1on3:A (1.9) BS02 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36479 1on3:B (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36480 1on3:B (1.9) BS02 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36481 1on3:C (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36482 1on3:C (1.9) BS02 DXX 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36483 1on3:C (1.9) BS03 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36484 1on3:D (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36485 1on3:D (1.9) BS02 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36486 1on3:E (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36487 1on3:E (1.9) BS02 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36488 1on3:F (1.9) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36489 1on3:F (1.9) BS02 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36490 1on3:F (1.9) BS03 DXX 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36491 1on6:A (2.3) BS01 UD1 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36492 1on6:B (2.3) BS01 UD1 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36493 1on8:A (2.7) BS01 BDP 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36494 1on8:A (2.7) BS02 UDP 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36495 1on8:B (2.7) BS01 BDP 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36496 1on8:B (2.7) BS02 UDP 2.4.1.223 GO:0016020 ... Q9ES89 12562774
    36497 1on9:A (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36498 1on9:B (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36499 1on9:C (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36500 1on9:D (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36501 1on9:E (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36502 1on9:F (2.0) BS01 MCA 2.1.3.1 GO:0003989 ... Q8GBW6 12743028
    36503 1ona:A (2.35) BS01 MAN ? GO:0030246 ... P02866 8940035
    36504 1ona:A (2.35) BS02 MAN ? GO:0030246 ... P02866 8940035
    36505 1ona:A (2.35) BS03 MN ? GO:0030246 ... P02866 8940035
    36506 1ona:A (2.35) BS04 CA ? GO:0030246 ... P02866 8940035
    36507 1ona:B (2.35) BS01 MMA ? GO:0030246 ... P02866 8940035
    36508 1ona:B (2.35) BS02 MAN ? GO:0030246 ... P02866 8940035
    36509 1ona:B (2.35) BS03 MAN ? GO:0030246 ... P02866 8940035
    36510 1ona:B (2.35) BS04 MN ? GO:0030246 ... P02866 8940035
    36511 1ona:B (2.35) BS05 CA ? GO:0030246 ... P02866 8940035
    36512 1ona:C (2.35) BS01 MAN ? GO:0030246 ... P02866 8940035
    36513 1ona:C (2.35) BS02 MAN ? GO:0030246 ... P02866 8940035
    36514 1ona:C (2.35) BS03 MN ? GO:0030246 ... P02866 8940035
    36515 1ona:C (2.35) BS04 CA ? GO:0030246 ... P02866 8940035
    36516 1ona:D (2.35) BS01 MAN ? GO:0030246 ... P02866 8940035
    36517 1ona:D (2.35) BS02 MAN ? GO:0030246 ... P02866 8940035
    36518 1ona:D (2.35) BS03 MN ? GO:0030246 ... P02866 8940035
    36519 1ona:D (2.35) BS04 CA ? GO:0030246 ... P02866 8940035
    36520 1onc:A (1.7) BS01 SO4 3.1.27.- GO:0003676 ... P22069 8120892
    36521 1ond:Q (3.4) BS01 rna ? GO:0003735 ... Q9RXJ7 12665853
    36522 1ond:Z (3.4) BS01 rna ? GO:0003735 ... P49228 12665853
    36523 1one:A (1.8) BS01 MG 4.2.1.11 GO:0000015 ... P00924 8605183
    36524 1one:A (1.8) BS02 PEP 4.2.1.11 GO:0000015 ... P00924 8605183
    36525 1one:A (1.8) BS03 2PG 4.2.1.11 GO:0000015 ... P00924 8605183
    36526 1one:B (1.8) BS01 MG 4.2.1.11 GO:0000015 ... P00924 8605183
    36527 1one:B (1.8) BS02 PEP 4.2.1.11 GO:0000015 ... P00924 8605183
    36528 1one:B (1.8) BS03 2PG 4.2.1.11 GO:0000015 ... P00924 8605183
    36529 1onf:A (2.6) BS01 FAD 1.8.1.7 GO:0004362 ... Q94655 12729762
    36530 1ong:A (1.1) BS01 MA4 3.5.2.6 GO:0008800 ... P0AD64 14609325
    36531 1ong:A (1.1) BS02 MA4 3.5.2.6 GO:0008800 ... P0AD64 14609325
    36532 1ong:A (1.1) BS03 WY4 3.5.2.6 GO:0008800 ... P0AD64 14609325 PDBbind: -logKd/Ki=8.05, IC50=9nM
    36533 1onh:A (1.38) BS01 WY4 3.5.2.6 GO:0008800 ... Q59401 14609325 PDBbind: -logKd/Ki=8.21, IC50=6.2nM
    36534 1onk:A (2.1) BS01 AZI 3.2.2.22 GO:0017148 ... P81446 N/A
    36535 1ono:A (2.5) BS01 MN 1.1.1.267 GO:0008299 ... P45568 12621040
    36536 1ono:B (2.5) BS01 MN 1.1.1.267 GO:0008299 ... P45568 12621040
    36537 1onp:A (2.5) BS01 MN 1.1.1.267 GO:0008299 ... P45568 12621040
    36538 1onp:A (2.5) BS02 FOM 1.1.1.267 GO:0008299 ... P45568 12621040 PDBbind: -logKd/Ki=7.52, IC50=0.030uM
    BindingDB: IC50=30nM
    36539 1onp:B (2.5) BS01 MN 1.1.1.267 GO:0008299 ... P45568 12621040
    36540 1onp:B (2.5) BS02 FOM 1.1.1.267 GO:0008299 ... P45568 12621040 BindingDB: IC50=30nM
    36541 1ons:A (2.2) BS01 ZN 3.1.2.-
    3.5.1.-
    3.5.1.124
    4.2.1.130
    GO:0005515 ... P31658 14500888
    36542 1onv:A (-1.00) BS01 peptide ? GO:0003677 ... P35269 12732728
    36543 1onw:A (1.65) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36544 1onw:A (1.65) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36545 1onw:B (1.65) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36546 1onw:B (1.65) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36547 1onx:A (2.1) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36548 1onx:A (2.1) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36549 1onx:A (2.1) BS03 ASP 3.4.19.- GO:0005737 ... P39377 12718528
    36550 1onx:B (2.1) BS01 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36551 1onx:B (2.1) BS02 ZN 3.4.19.- GO:0005737 ... P39377 12718528
    36552 1onx:B (2.1) BS03 ASP 3.4.19.- GO:0005737 ... P39377 12718528
    36553 1ony:A (2.15) BS01 588 3.1.3.48 GO:0004725 ... P18031 12747781 PDBbind: -logKd/Ki=6.77, Ki=0.17uM
    BindingDB: Ki=170nM
    36554 1onz:A (2.4) BS01 968 3.1.3.48 GO:0004725 ... P18031 12747781 PDBbind: -logKd/Ki=5.10, Kd=8uM
    BindingDB: Ki=25119nM
    36555 1oo5:A (2.5) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36556 1oo5:A (2.5) BS02 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36557 1oo5:B (2.5) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36558 1oo5:B (2.5) BS02 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36559 1oo6:A (2.0) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36560 1oo6:A (2.0) BS02 SN2 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36561 1oo6:A (2.0) BS03 SN2 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36562 1oo6:A (2.0) BS04 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36563 1oo6:B (2.0) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36564 1oo6:B (2.0) BS02 SN2 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36565 1oo6:B (2.0) BS03 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36566 1ooa:A (2.45) BS01 rna ? GO:0003677 ... P25799 12886018
    36567 1ooa:B (2.45) BS01 rna ? GO:0003677 ... P25799 12886018
    36568 1oog:A (1.45) BS01 POL ? GO:0005549 ... O02372 12881720
    36569 1oog:B (1.45) BS01 POL ? GO:0005549 ... O02372 12881720
    36570 1ooh:A (1.25) BS01 1BO ? GO:0005549 ... O02372 12881720
    36571 1ooh:B (1.25) BS01 1BO ? GO:0005549 ... O02372 12881720
    36572 1ooj:A (2.11) BS01 CA ? GO:0005509 ... O16305 14635136
    36573 1ooj:A (2.11) BS02 CA ? GO:0005509 ... O16305 14635136
    36574 1ooj:A (2.11) BS03 CA ? GO:0005509 ... O16305 14635136
    36575 1ooj:A (2.11) BS04 CA ? GO:0005509 ... O16305 14635136
    36576 1ook:B (2.3) BS01 peptide 3.4.21.5 GO:0004252 ... P00734 12855810
    36577 1oon:A (2.49) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36578 1oon:A (2.49) BS02 BEL 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36579 1oon:A (2.49) BS03 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36580 1oon:B (2.49) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36581 1oon:B (2.49) BS02 BEL 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36582 1oon:B (2.49) BS03 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36583 1ooq:A (2.0) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36584 1ooq:A (2.0) BS02 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36585 1ooq:A (2.0) BS03 DTC 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36586 1ooq:B (2.0) BS01 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36587 1ooq:B (2.0) BS02 FMN 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36588 1ooq:B (2.0) BS03 DTC 1.-.-.-
    1.5.1.34
    GO:0003955 ... P38489 12954054
    36589 1oow:A (2.0) BS01 CU ? GO:0005507 ... P00289 14670610
    36590 1op0:A (2.0) BS01 FUC 3.4.21.- GO:0004252 ... Q9I8X1 15632114
    36591 1opb:A (1.9) BS01 RET ? GO:0005504 ... P06768 8487303 MOAD: Kd=50nM
    36592 1opb:B (1.9) BS01 RET ? GO:0005504 ... P06768 8487303 MOAD: Kd=50nM
    36593 1opb:C (1.9) BS01 RET ? GO:0005504 ... P06768 8487303 MOAD: Kd=50nM
    36594 1opb:D (1.9) BS01 RET ? GO:0005504 ... P06768 8487303 MOAD: Kd=50nM
    36595 1opi:A (-1.00) BS01 peptide ? GO:0003676 ... P26368 12718882
    36596 1opj:A (1.75) BS01 STI 2.7.10.2 GO:0004672 ... P00520 12654251 BindingDB: IC50=10.8nM
    36597 1opj:B (1.75) BS01 STI 2.7.10.2 GO:0004672 ... P00520 12654251 BindingDB: IC50=10.8nM
    36598 1opk:A (1.8) BS01 P16 2.7.10.2 GO:0004672 ... P00520 12654251
    36599 1opl:A (3.42) BS01 P16 2.7.10.2 GO:0004672 ... P00519 12654251 BindingDB: IC50=2.8nM
    36600 1opl:B (3.42) BS01 P16 2.7.10.2 GO:0004672 ... P00519 12654251 BindingDB: IC50=2.8nM

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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