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BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    27201 1l9h:A (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    27202 1l9h:B (2.6) BS01 ZN ? GO:0000139 ... P02699 11972040
    27203 1l9h:B (2.6) BS02 ZN ? GO:0000139 ... P02699 11972040
    27204 1l9h:B (2.6) BS03 ZN ? GO:0000139 ... P02699 11972040
    27205 1l9h:B (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    27206 1l9j:C (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    27207 1l9j:D (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    27208 1l9j:L (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    27209 1l9j:L (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    27210 1l9j:L (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    27211 1l9j:L (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    27212 1l9j:L (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    27213 1l9j:L (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    27214 1l9j:M (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    27215 1l9j:M (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    27216 1l9j:M (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    27217 1l9j:M (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    27218 1l9j:M (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    27219 1l9j:M (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    27220 1l9j:M (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    27221 1l9j:R (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    27222 1l9j:R (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    27223 1l9j:R (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    27224 1l9j:R (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    27225 1l9j:R (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    27226 1l9j:R (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    27227 1l9j:S (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    27228 1l9j:S (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    27229 1l9j:S (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    27230 1l9j:S (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    27231 1l9j:S (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    27232 1l9j:S (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    27233 1l9j:S (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    27234 1l9k:A (2.4) BS01 SAH 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13
    GO:0003968 ... P12823 12032088
    27235 1l9l:A (0.92) BS01 SO4 ? GO:0042742 ... P22749 12488100
    27236 1l9l:A (0.92) BS02 SO4 ? GO:0042742 ... P22749 12488100
    27237 1l9l:A (0.92) BS03 SO4 ? GO:0042742 ... P22749 12488100
    27238 1l9m:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27239 1l9m:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27240 1l9n:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27241 1l9n:A (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27242 1l9n:A (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27243 1l9n:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27244 1l9n:B (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27245 1l9n:B (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    27246 1l9o:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27247 1l9o:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27248 1l9o:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27249 1l9o:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27250 1l9o:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27251 1l9o:C (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27252 1l9o:C (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27253 1l9p:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27254 1l9p:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27255 1l9p:B (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27256 1l9p:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27257 1l9p:C (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27258 1l9p:C (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27259 1l9q:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27260 1l9q:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27261 1l9q:A (1.7) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27262 1l9q:A (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27263 1l9q:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27264 1l9q:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27265 1l9q:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27266 1l9q:B (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27267 1l9q:C (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27268 1l9q:C (1.7) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27269 1l9q:C (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27270 1l9q:C (1.7) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27271 1l9r:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27272 1l9r:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27273 1l9r:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27274 1l9r:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27275 1l9r:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27276 1l9r:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27277 1l9r:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27278 1l9r:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27279 1l9r:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27280 1l9s:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27281 1l9s:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27282 1l9s:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27283 1l9s:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27284 1l9s:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27285 1l9s:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27286 1l9s:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27287 1l9s:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27288 1l9s:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27289 1l9t:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27290 1l9t:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27291 1l9t:A (1.75) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27292 1l9t:A (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27293 1l9t:B (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27294 1l9t:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27295 1l9t:B (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27296 1l9t:B (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27297 1l9t:C (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27298 1l9t:C (1.75) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    27299 1l9t:C (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27300 1l9t:C (1.75) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    27301 1l9w:A (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    27302 1l9w:B (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    27303 1l9w:C (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    27304 1l9w:D (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    27305 1la0:A (-1.00) BS01 CA ? GO:0003009 ... P09860 12147696
    27306 1la0:A (-1.00) BS02 CA ? GO:0003009 ... P09860 12147696
    27307 1la0:A (-1.00) BS03 CA ? GO:0003009 ... P09860 12147696
    27308 1la2:A (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    27309 1la2:B (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    27310 1la2:C (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    27311 1la2:D (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    27312 1la3:A (-1.00) BS01 CA ? GO:0001750 ... P21457 11980481
    27313 1la6:A (2.0) BS01 HEM ? GO:0004601 ... P45718 12093902
    27314 1la6:B (2.0) BS01 HEM ? GO:0004601 ... P45720 12093902
    27315 1laf:E (2.06) BS01 ARG ? GO:0006865 ... P02911 7929349 MOAD: Kd=14nM
    PDBbind: -logKd/Ki=7.85, Kd=14nM
    27316 1lag:E (2.06) BS01 HIS ? GO:0006865 ... P02911 7929349 MOAD: Kd=500nM
    PDBbind: -logKd/Ki=6.30, Kd=500nM
    27317 1lah:E (2.06) BS01 ORN ? GO:0006865 ... P02911 7929349 MOAD: Kd=30nM
    PDBbind: -logKd/Ki=7.52, Kd=30nM
    27318 1lam:A (1.6) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    27319 1lam:A (1.6) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    27320 1lam:A (1.6) BS03 CO3 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    27321 1lan:A (1.9) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    27322 1lan:A (1.9) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    27323 1lan:A (1.9) BS03 LEU 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088 MOAD: Ki=60nM
    PDBbind: -logKd/Ki=7.22, Ki=60nM
    27324 1lap:A (2.7) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    27325 1lap:A (2.7) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    27326 1lat:A (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    27327 1lat:A (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    27328 1lat:A (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    27329 1lat:A (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    27330 1lat:B (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    27331 1lat:B (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    27332 1lat:B (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    27333 1lat:B (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    27334 1lau:E (1.8) BS01 dna 3.2.2.27 GO:0004844 ... P10186 7845459
    27335 1lax:A (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    27336 1lax:A (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028
    27337 1lax:C (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    27338 1lax:C (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028
    27339 1lb2:A (3.1) BS01 dna ? GO:0003677 ... P0ACJ8 12202833
    27340 1lb2:A (3.1) BS02 dna ? GO:0003677 ... P0ACJ8 12202833
    27341 1lb2:A (3.1) BS03 CMP ? GO:0003677 ... P0ACJ8 12202833
    27342 1lb2:B (3.1) BS01 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    27343 1lb2:B (3.1) BS02 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    27344 1lb2:E (3.1) BS01 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    27345 1lb2:E (3.1) BS02 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    27346 1lb3:A (1.21) BS01 CD ? GO:0005506 ... P29391 12459904
    27347 1lb3:A (1.21) BS02 CD ? GO:0005506 ... P29391 12459904
    27348 1lb3:A (1.21) BS03 CD ? GO:0005506 ... P29391 12459904
    27349 1lb3:A (1.21) BS04 GOL ? GO:0005506 ... P29391 12459904
    27350 1lb3:A (1.21) BS05 GOL ? GO:0005506 ... P29391 12459904
    27351 1lb5:A (2.4) BS01 peptide 2.3.2.27 GO:0004842 ... Q9Y4K3 12140561
    27352 1lb6:A (1.8) BS01 peptide 2.3.2.27 GO:0004842 ... Q9Y4K3 12140561
    27353 1lb8:A (2.3) BS01 AMQ ? GO:0015276 ... P19491 12015593 BindingDB: Ki=17nM
    27354 1lb8:B (2.3) BS01 AMQ ? GO:0015276 ... P19491 12015593 BindingDB: Ki=17nM
    27355 1lb9:A (2.3) BS01 DNQ ? GO:0015276 ... P19491 12015593
    27356 1lb9:B (2.3) BS01 DNQ ? GO:0015276 ... P19491 12015593
    27357 1lba:A (2.2) BS01 ZN 3.5.1.28 GO:0008270 ... P00806 8171031
    27358 1lbc:A (1.8) BS01 ZN ? GO:0015276 ... P19491 12015593
    27359 1lbc:A (1.8) BS02 GLU ? GO:0015276 ... P19491 12015593
    27360 1lbc:A (1.8) BS03 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    27361 1lbc:A (1.8) BS04 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    27362 1lbc:B (1.8) BS01 ZN ? GO:0015276 ... P19491 12015593
    27363 1lbc:B (1.8) BS02 ZN ? GO:0015276 ... P19491 12015593
    27364 1lbc:B (1.8) BS03 GLU ? GO:0015276 ... P19491 12015593
    27365 1lbc:B (1.8) BS04 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    27366 1lbc:C (1.8) BS01 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    27367 1lbc:C (1.8) BS02 GLU ? GO:0015276 ... P19491 12015593
    27368 1lbc:C (1.8) BS03 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    27369 1lbf:A (2.05) BS01 137 4.1.1.48 GO:0000162 ... Q06121 12054868 MOAD: Kd=0.014uM
    PDBbind: -logKd/Ki=7.85, Kd=0.014uM
    27370 1lbg:A (4.8) BS01 dna ? GO:0000976 ... P03023 8638105
    27371 1lbg:D (4.8) BS01 dna ? GO:0000976 ... P03023 8638105
    27372 1lbh:A (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    27373 1lbh:B (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    27374 1lbh:C (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    27375 1lbh:D (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    27376 1lbk:A (1.86) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 12473455 MOAD: Kd=668uM
    27377 1lbk:B (1.86) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 12473455 MOAD: Kd=668uM
    27378 1lbl:A (2.4) BS01 137 4.1.1.48 GO:0000162 ... Q06121 12054868 MOAD: Kd=0.014uM
    27379 1lbm:A (2.8) BS01 137 5.3.1.24 GO:0000162 ... Q56320 12356303
    27380 1lbs:A (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27381 1lbs:B (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27382 1lbs:C (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27383 1lbs:D (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27384 1lbs:E (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27385 1lbs:F (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    27386 1lbt:A (2.5) BS01 T80 3.1.1.3 GO:0004806 ... P41365 8527460
    27387 1lbt:B (2.5) BS01 T80 3.1.1.3 GO:0004806 ... P41365 8527460
    27388 1lbu:A (1.8) BS01 ZN 3.4.17.14 GO:0004180 ... P00733 N/A
    27389 1lbx:A (2.4) BS01 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27390 1lbx:A (2.4) BS02 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27391 1lbx:A (2.4) BS03 IPD 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27392 1lbx:B (2.4) BS01 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27393 1lbx:B (2.4) BS02 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27394 1lbx:B (2.4) BS03 IPD 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27395 1lby:A (2.25) BS01 F6P 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27396 1lby:A (2.25) BS02 MN 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27397 1lby:A (2.25) BS03 MN 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27398 1lby:A (2.25) BS04 MN 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27399 1lby:A (2.25) BS05 PO4 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    27400 1lby:A (2.25) BS06 F6P 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218