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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
Download all results in tab-seperated text for 817662 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    26401 1kwk:A (2.2) BS01 GAL 3.2.1.23 GO:0004565 ... O69315 12215416
    26402 1kwk:A (2.2) BS02 ZN 3.2.1.23 GO:0004565 ... O69315 12215416
    26403 1kwm:A (1.6) BS01 ZN 3.4.17.2 GO:0004180 ... P15086 12162965
    26404 1kwm:B (1.6) BS01 ZN 3.4.17.2 GO:0004180 ... P15086 12162965
    26405 1kwo:A (3.8) BS01 MG ? GO:0003774 ... P24733 12297624
    26406 1kwo:A (3.8) BS02 AGS ? GO:0003774 ... P24733 12297624
    26407 1kwo:A (3.8) BS03 PDM ? GO:0003774 ... P24733 12297624
    26408 1kwo:B (3.8) BS01 MG ? GO:0005509 ... P13543 12297624
    26409 1kwo:C (3.8) BS01 CA ? GO:0005509 ... P07291 12297624
    26410 1kwq:A (2.6) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12166932
    26411 1kwq:A (2.6) BS02 SG1 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12166932 PDBbind: -logKd/Ki=9.21, IC50=0.62nM
    BindingDB: IC50=0.62nM
    26412 1kwr:A (2.25) BS01 ZN 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12166932
    26413 1kwr:A (2.25) BS02 SG2 4.2.1.1
    4.2.1.69
    GO:0002009 ... P00918 12166932 MOAD: ic50=0.25uM
    PDBbind: -logKd/Ki=6.60, IC50=0.25uM
    BindingDB: IC50=245.5nM
    26414 1kws:A (2.1) BS01 MN 2.4.1.135 GO:0015018 ... O94766 11950836
    26415 1kws:A (2.1) BS02 UGA 2.4.1.135 GO:0015018 ... O94766 11950836
    26416 1kws:B (2.1) BS01 UGA 2.4.1.135 GO:0015018 ... O94766 11950836
    26417 1kx2:A (-1.00) BS01 HEC ? GO:0005506 ... O52685 11955059
    26418 1kx3:A (2.0) BS01 dna ? GO:0000786 ... P84233 12079350
    26419 1kx3:A (2.0) BS02 dna ? GO:0000786 ... P84233 12079350
    26420 1kx3:B (2.0) BS01 dna ? GO:0000786 ... P62799 12079350
    26421 1kx3:B (2.0) BS02 dna ? GO:0000786 ... P62799 12079350
    26422 1kx3:C (2.0) BS01 dna ? GO:0000786 ... P06897 12079350
    26423 1kx3:C (2.0) BS02 dna ? GO:0000786 ... P06897 12079350
    26424 1kx3:D (2.0) BS01 dna ? GO:0000786 ... P02281 12079350
    26425 1kx3:D (2.0) BS02 dna ? GO:0000786 ... P02281 12079350
    26426 1kx3:E (2.0) BS01 dna ? GO:0000786 ... P84233 12079350
    26427 1kx3:E (2.0) BS02 dna ? GO:0000786 ... P84233 12079350
    26428 1kx3:F (2.0) BS01 dna ? GO:0000786 ... P62799 12079350
    26429 1kx3:F (2.0) BS02 dna ? GO:0000786 ... P62799 12079350
    26430 1kx3:G (2.0) BS01 dna ? GO:0000786 ... P06897 12079350
    26431 1kx3:G (2.0) BS02 dna ? GO:0000786 ... P06897 12079350
    26432 1kx3:H (2.0) BS01 dna ? GO:0000786 ... P02281 12079350
    26433 1kx3:H (2.0) BS02 dna ? GO:0000786 ... P02281 12079350
    26434 1kx4:A (2.6) BS01 dna ? GO:0000786 ... P84233 12079350
    26435 1kx4:A (2.6) BS02 dna ? GO:0000786 ... P84233 12079350
    26436 1kx4:B (2.6) BS01 dna ? GO:0000786 ... P62799 12079350
    26437 1kx4:B (2.6) BS02 dna ? GO:0000786 ... P62799 12079350
    26438 1kx4:C (2.6) BS01 dna ? GO:0000786 ... P06897 12079350
    26439 1kx4:C (2.6) BS02 dna ? GO:0000786 ... P06897 12079350
    26440 1kx4:D (2.6) BS01 dna ? GO:0000786 ... P02281 12079350
    26441 1kx4:D (2.6) BS02 dna ? GO:0000786 ... P02281 12079350
    26442 1kx4:E (2.6) BS01 dna ? GO:0000786 ... P84233 12079350
    26443 1kx4:E (2.6) BS02 dna ? GO:0000786 ... P84233 12079350
    26444 1kx4:F (2.6) BS01 dna ? GO:0000786 ... P62799 12079350
    26445 1kx4:F (2.6) BS02 dna ? GO:0000786 ... P62799 12079350
    26446 1kx4:G (2.6) BS01 dna ? GO:0000786 ... P06897 12079350
    26447 1kx4:G (2.6) BS02 dna ? GO:0000786 ... P06897 12079350
    26448 1kx4:H (2.6) BS01 dna ? GO:0000786 ... P02281 12079350
    26449 1kx4:H (2.6) BS02 dna ? GO:0000786 ... P02281 12079350
    26450 1kx5:A (1.94) BS01 dna ? GO:0000786 ... P84233 12079350
    26451 1kx5:A (1.94) BS02 dna ? GO:0000786 ... P84233 12079350
    26452 1kx5:B (1.94) BS01 dna ? GO:0000786 ... P62799 12079350
    26453 1kx5:B (1.94) BS02 dna ? GO:0000786 ... P62799 12079350
    26454 1kx5:C (1.94) BS01 dna ? GO:0000786 ... P06897 12079350
    26455 1kx5:C (1.94) BS02 dna ? GO:0000786 ... P06897 12079350
    26456 1kx5:D (1.94) BS01 dna ? GO:0000786 ... P02281 12079350
    26457 1kx5:D (1.94) BS02 dna ? GO:0000786 ... P02281 12079350
    26458 1kx5:E (1.94) BS01 dna ? GO:0000786 ... P84233 12079350
    26459 1kx5:E (1.94) BS02 dna ? GO:0000786 ... P84233 12079350
    26460 1kx5:F (1.94) BS01 dna ? GO:0000786 ... P62799 12079350
    26461 1kx5:F (1.94) BS02 dna ? GO:0000786 ... P62799 12079350
    26462 1kx5:G (1.94) BS01 dna ? GO:0000786 ... P06897 12079350
    26463 1kx5:G (1.94) BS02 dna ? GO:0000786 ... P06897 12079350
    26464 1kx5:H (1.94) BS01 dna ? GO:0000786 ... P02281 12079350
    26465 1kx5:H (1.94) BS02 dna ? GO:0000786 ... P02281 12079350
    26466 1kx7:A (-1.00) BS01 HEC ? GO:0005506 ... O52685 11955059
    26467 1kxg:A (2.0) BS01 MG ? GO:0005164 ... Q9Y275 11862220
    26468 1kxg:F (2.0) BS01 MG ? GO:0005164 ... Q9Y275 11862220
    26469 1kxh:A (2.3) BS01 GLC 3.2.1.1 GO:0003824 ... P29957 11914073
    26470 1kxh:A (2.3) BS02 GLC 3.2.1.1 GO:0003824 ... P29957 11914073
    26471 1kxh:A (2.3) BS03 AC1 3.2.1.1 GO:0003824 ... P29957 11914073
    26472 1kxh:A (2.3) BS04 CA 3.2.1.1 GO:0003824 ... P29957 11914073
    26473 1kxm:A (1.74) BS01 HEM 1.11.1.5 GO:0004601 ... P00431 11967381
    26474 1kxm:A (1.74) BS02 BZI 1.11.1.5 GO:0004601 ... P00431 11967381 MOAD: Kd=0.14mM
    26475 1kxn:A (1.8) BS01 HEM 1.11.1.5 GO:0004601 ... P00431 11967381
    26476 1kxp:A (2.1) BS01 ATP 3.6.4.- GO:0000287 ... P68135 12048248
    26477 1kxq:A (1.6) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26478 1kxq:B (1.6) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26479 1kxq:C (1.6) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26480 1kxq:D (1.6) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26481 1kxr:A (2.07) BS01 CA 3.4.22.52 GO:0004198 ... P97571 11893336
    26482 1kxr:A (2.07) BS02 CA 3.4.22.52 GO:0004198 ... P97571 11893336
    26483 1kxr:B (2.07) BS01 CA 3.4.22.52 GO:0004198 ... P97571 11893336
    26484 1kxr:B (2.07) BS02 CA 3.4.22.52 GO:0004198 ... P97571 11893336
    26485 1kxt:A (2.0) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26486 1kxt:C (2.0) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26487 1kxt:E (2.0) BS01 CA 3.2.1.1 GO:0003824 ... P00690 11960990
    26488 1ky2:A (1.6) BS01 MG ? GO:0003924 ... P32939 11937061
    26489 1ky2:A (1.6) BS02 GNP ? GO:0003924 ... P32939 11937061
    26490 1ky3:A (1.35) BS01 GDP ? GO:0003924 ... P32939 11937061
    26491 1ky4:A (2.8) BS01 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26492 1ky4:A (2.8) BS02 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26493 1ky4:B (2.8) BS01 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26494 1ky4:B (2.8) BS02 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26495 1ky4:C (2.8) BS01 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26496 1ky4:C (2.8) BS02 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26497 1ky4:D (2.8) BS01 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26498 1ky4:D (2.8) BS02 NAD 3.13.2.1 GO:0001666 ... P10760 11927587
    26499 1ky5:A (2.8) BS01 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26500 1ky5:A (2.8) BS02 ADY 3.13.2.1 GO:0001666 ... P10760 11927587
    26501 1ky5:A (2.8) BS03 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26502 1ky5:B (2.8) BS01 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26503 1ky5:B (2.8) BS02 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26504 1ky5:B (2.8) BS03 ADY 3.13.2.1 GO:0001666 ... P10760 11927587
    26505 1ky5:C (2.8) BS01 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26506 1ky5:C (2.8) BS02 ADY 3.13.2.1 GO:0001666 ... P10760 11927587
    26507 1ky5:C (2.8) BS03 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26508 1ky5:D (2.8) BS01 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26509 1ky5:D (2.8) BS02 NAI 3.13.2.1 GO:0001666 ... P10760 11927587
    26510 1ky5:D (2.8) BS03 ADY 3.13.2.1 GO:0001666 ... P10760 11927587
    26511 1ky6:A (2.0) BS01 peptide ? GO:0006886 ... P17427 12057195
    26512 1ky7:A (2.15) BS01 peptide ? GO:0006886 ... P17427 12057195
    26513 1ky8:A (2.4) BS01 NAP 1.2.1.90 GO:0000166 ... O57693 11842090 MOAD: Kd=1uM
    26514 1kya:A (2.4) BS01 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26515 1kya:A (2.4) BS02 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26516 1kya:A (2.4) BS03 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26517 1kya:A (2.4) BS04 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26518 1kya:A (2.4) BS05 XYD 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26519 1kya:B (2.4) BS01 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26520 1kya:B (2.4) BS02 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26521 1kya:B (2.4) BS03 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26522 1kya:B (2.4) BS04 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26523 1kya:B (2.4) BS05 XYD 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26524 1kya:C (2.4) BS01 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26525 1kya:C (2.4) BS02 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26526 1kya:C (2.4) BS03 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26527 1kya:C (2.4) BS04 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26528 1kya:C (2.4) BS05 XYD 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26529 1kya:D (2.4) BS01 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26530 1kya:D (2.4) BS02 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26531 1kya:D (2.4) BS03 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26532 1kya:D (2.4) BS04 CU 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26533 1kya:D (2.4) BS05 XYD 1.10.3.2 GO:0005507 ... Q96UT7 12044164
    26534 1kyd:A (2.0) BS01 peptide ? GO:0006886 ... P17427 12057195
    26535 1kyf:A (1.22) BS01 peptide ? GO:0006886 ... P17427 12057195
    26536 1kyi:A (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26537 1kyi:B (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26538 1kyi:C (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26539 1kyi:D (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26540 1kyi:E (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26541 1kyi:F (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26542 1kyi:G (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26543 1kyi:H (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26544 1kyi:I (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26545 1kyi:J (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26546 1kyi:K (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26547 1kyi:L (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26548 1kyi:M (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26549 1kyi:N (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26550 1kyi:O (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26551 1kyi:P (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26552 1kyi:Q (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26553 1kyi:R (3.1) BS01 LVS 3.4.25.2 GO:0004298 ... P43772 12054822
    26554 1kyi:S (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26555 1kyi:T (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26556 1kyi:U (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26557 1kyi:V (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26558 1kyi:W (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26559 1kyi:X (3.1) BS01 ATP ? GO:0005515 ... P43773 12054822
    26560 1kyn:A (3.5) BS01 KTP 3.4.21.20 GO:0002003 ... P08311 11942800 PDBbind: -logKd/Ki=5.39, IC50=4.1uM
    BindingDB: IC50=4100nM
    26561 1kyn:B (3.5) BS01 KTP 3.4.21.20 GO:0002003 ... P08311 11942800 BindingDB: IC50=4100nM
    26562 1kyo:C (2.97) BS01 HEC 7.1.1.8 GO:0005739 ... P00163 11880631
    26563 1kyo:C (2.97) BS02 HEC 7.1.1.8 GO:0005739 ... P00163 11880631
    26564 1kyo:C (2.97) BS03 SMA 7.1.1.8 GO:0005739 ... P00163 11880631
    26565 1kyo:D (2.97) BS01 HEC 7.1.1.8 GO:0009055 ... P07143 11880631
    26566 1kyo:E (2.97) BS01 FES 7.1.1.8 GO:0008121 ... P08067 11880631
    26567 1kyo:E (2.97) BS02 SMA 7.1.1.8 GO:0008121 ... P08067 11880631
    26568 1kyo:N (2.97) BS01 HEC 7.1.1.8 GO:0005739 ... P00163 11880631
    26569 1kyo:N (2.97) BS02 HEC 7.1.1.8 GO:0005739 ... P00163 11880631
    26570 1kyo:N (2.97) BS03 SMA 7.1.1.8 GO:0005739 ... P00163 11880631
    26571 1kyo:O (2.97) BS01 HEC 7.1.1.8 GO:0009055 ... P07143 11880631
    26572 1kyo:P (2.97) BS01 FES 7.1.1.8 GO:0008121 ... P08067 11880631
    26573 1kyo:W (2.97) BS01 HEC ? GO:0005515 ... P00044 11880631
    26574 1kyq:A (2.2) BS01 NAD 1.3.1.76
    4.99.1.4
    GO:0000103 ... P15807 11980703
    26575 1kyq:B (2.2) BS01 NAD 1.3.1.76
    4.99.1.4
    GO:0000103 ... P15807 11980703
    26576 1kyq:C (2.2) BS01 NAD 1.3.1.76
    4.99.1.4
    GO:0000103 ... P15807 11980703
    26577 1kyr:A (1.5) BS01 CU ? GO:0003674 ... P42212 11929238
    26578 1kys:A (1.44) BS01 ZN ? GO:0003674 ... P42212 11929238
    26579 1kyt:A (1.7) BS01 CA 3.1.3.18 GO:0000287 ... Q9HLQ2 N/A
    26580 1kyt:A (1.7) BS02 CA 3.1.3.18 GO:0000287 ... Q9HLQ2 N/A
    26581 1kyt:A (1.7) BS03 CA 3.1.3.18 GO:0000287 ... Q9HLQ2 N/A
    26582 1kyt:B (1.7) BS01 CA 3.1.3.18 GO:0000287 ... Q9HLQ2 N/A
    26583 1kyt:B (1.7) BS02 CA 3.1.3.18 GO:0000287 ... Q9HLQ2 N/A
    26584 1kyu:A (1.8) BS01 peptide ? GO:0006886 ... P17427 12057195
    26585 1kyv:A (2.4) BS01 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26586 1kyv:A (2.4) BS02 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26587 1kyv:B (2.4) BS01 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26588 1kyv:B (2.4) BS02 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26589 1kyv:C (2.4) BS01 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26590 1kyv:C (2.4) BS02 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26591 1kyv:D (2.4) BS01 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26592 1kyv:D (2.4) BS02 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26593 1kyv:E (2.4) BS01 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26594 1kyv:E (2.4) BS02 RBF 2.5.1.78 GO:0000906 ... Q9UUB1 12083520 MOAD: Kd=1.2uM
    26595 1kyw:C (2.4) BS01 SAH 2.1.1.68 GO:0008168 ... P28002 12084826
    26596 1kyw:F (2.4) BS01 SAH 2.1.1.68 GO:0008168 ... P28002 12084826
    26597 1kyw:F (2.4) BS02 HFL 2.1.1.68 GO:0008168 ... P28002 12084826
    26598 1kyx:A (2.6) BS01 CRM 2.5.1.78 GO:0000906 ... Q9UUB1 12083520
    26599 1kyx:A (2.6) BS02 CRM 2.5.1.78 GO:0000906 ... Q9UUB1 12083520
    26600 1kyx:B (2.6) BS01 CRM 2.5.1.78 GO:0000906 ... Q9UUB1 12083520

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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