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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    15601 1gqc:A (2.6) BS01 MG 2.7.7.38 GO:0005737 ... P42216 11802716
    15602 1gqc:A (2.6) BS02 CMK 2.7.7.38 GO:0005737 ... P42216 11802716
    15603 1gqc:B (2.6) BS01 MG 2.7.7.38 GO:0005737 ... P42216 11802716
    15604 1gqc:B (2.6) BS02 C5P 2.7.7.38 GO:0005737 ... P42216 11802716
    15605 1gqg:A (1.7) BS01 DCD 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15606 1gqg:A (1.7) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15607 1gqg:B (1.7) BS01 DCD 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15608 1gqg:B (1.7) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15609 1gqg:C (1.7) BS01 DCD 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15610 1gqg:C (1.7) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15611 1gqg:D (1.7) BS01 DCD 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15612 1gqg:D (1.7) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15613 1gqh:A (2.15) BS01 KOJ 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15614 1gqh:A (2.15) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15615 1gqh:B (2.15) BS01 KOJ 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15616 1gqh:B (2.15) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15617 1gqh:C (2.15) BS01 KOJ 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15618 1gqh:C (2.15) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15619 1gqh:D (2.15) BS01 KOJ 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15620 1gqh:D (2.15) BS02 CU 1.13.11.24 GO:0008127 ... Q7SIC2 12069585
    15621 1gqi:A (1.48) BS01 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15622 1gqi:A (1.48) BS02 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15623 1gqi:A (1.48) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15624 1gqi:B (1.48) BS01 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15625 1gqi:B (1.48) BS02 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15626 1gqi:B (1.48) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15627 1gqi:B (1.48) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15628 1gqj:A (1.9) BS01 XYP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15629 1gqj:A (1.9) BS02 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15630 1gqj:A (1.9) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15631 1gqj:A (1.9) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15632 1gqj:A (1.9) BS05 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15633 1gqj:B (1.9) BS01 XYP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15634 1gqj:B (1.9) BS02 XYP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15635 1gqj:B (1.9) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15636 1gqj:B (1.9) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15637 1gqj:B (1.9) BS05 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15638 1gqk:A (1.9) BS01 BDP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15639 1gqk:A (1.9) BS02 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15640 1gqk:A (1.9) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15641 1gqk:A (1.9) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15642 1gqk:B (1.9) BS01 BDP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15643 1gqk:B (1.9) BS02 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15644 1gqk:B (1.9) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15645 1gqk:B (1.9) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15646 1gql:A (1.67) BS01 XYP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15647 1gql:A (1.67) BS02 BDP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15648 1gql:A (1.67) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15649 1gql:A (1.67) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15650 1gql:A (1.67) BS05 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15651 1gql:A (1.67) BS06 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15652 1gql:B (1.67) BS01 XYP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15653 1gql:B (1.67) BS02 BDP 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15654 1gql:B (1.67) BS03 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15655 1gql:B (1.67) BS04 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15656 1gql:B (1.67) BS05 CO 3.2.1.131 GO:0004553 ... B3PC73 11937059
    15657 1gqm:A (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15658 1gqm:A (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15659 1gqm:A (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15660 1gqm:B (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15661 1gqm:B (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15662 1gqm:B (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15663 1gqm:C (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15664 1gqm:C (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15665 1gqm:C (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15666 1gqm:D (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15667 1gqm:D (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15668 1gqm:D (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15669 1gqm:E (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15670 1gqm:E (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15671 1gqm:E (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15672 1gqm:F (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15673 1gqm:F (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15674 1gqm:F (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15675 1gqm:G (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15676 1gqm:G (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15677 1gqm:G (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15678 1gqm:H (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15679 1gqm:H (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15680 1gqm:H (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15681 1gqm:I (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15682 1gqm:I (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15683 1gqm:I (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15684 1gqm:J (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15685 1gqm:J (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15686 1gqm:J (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15687 1gqm:K (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15688 1gqm:K (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15689 1gqm:K (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15690 1gqm:L (2.7) BS01 CA ? GO:0002548 ... P80511 11856825
    15691 1gqm:L (2.7) BS02 CA ? GO:0002548 ... P80511 11856825
    15692 1gqm:L (2.7) BS03 CA ? GO:0002548 ... P80511 11856825
    15693 1gqr:A (2.2) BS01 SAF 3.1.1.7 GO:0001507 ... P04058 11888271 BindingDB: Ki=700nM
    15694 1gqr:A (2.2) BS02 EMM 3.1.1.7 GO:0001507 ... P04058 11888271
    15695 1gqs:A (3.0) BS01 SAF 3.1.1.7 GO:0001507 ... P04058 11888271 PDBbind: -logKd/Ki=6.30, Ki=0.5uM
    BindingDB: Ki=700nM
    15696 1gqt:A (2.34) BS01 CS 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15697 1gqt:A (2.34) BS02 ACP 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15698 1gqt:A (2.34) BS03 RIB 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15699 1gqt:B (2.34) BS01 CS 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15700 1gqt:B (2.34) BS02 ACP 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15701 1gqt:B (2.34) BS03 RIB 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15702 1gqt:C (2.34) BS01 CS 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15703 1gqt:C (2.34) BS02 ACP 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15704 1gqt:C (2.34) BS03 RIB 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15705 1gqt:D (2.34) BS01 CS 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15706 1gqt:D (2.34) BS02 RIB 2.7.1.15 GO:0004747 ... P0A9J6 11786021
    15707 1gqw:A (3.0) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 11955067
    15708 1gqw:A (3.0) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 11955067
    15709 1gqw:B (3.0) BS01 FE2 1.14.11.17 GO:0000908 ... P37610 11955067
    15710 1gqw:B (3.0) BS02 AKG 1.14.11.17 GO:0000908 ... P37610 11955067
    15711 1gqy:A (1.8) BS01 ACP 6.3.2.8 GO:0005524 ... P45066 N/A
    15712 1gqy:A (1.8) BS02 MG 6.3.2.8 GO:0005524 ... P45066 N/A
    15713 1gqy:B (1.8) BS01 ACP 6.3.2.8 GO:0005524 ... P45066 N/A
    15714 1gqy:B (1.8) BS02 MG 6.3.2.8 GO:0005524 ... P45066 N/A
    15715 1gr0:A (1.95) BS01 NAD 5.5.1.4 GO:0004512 ... P9WKI1 12005437
    15716 1gr1:A (2.5) BS01 FAD 1.18.1.2 GO:0016491 ... P21890 12383252
    15717 1gr2:A (1.9) BS01 KAI ? GO:0015276 ... P19491 9804426 BindingDB: EC50=380000nM, Ki=3690nM
    15718 1gr3:A (2.0) BS01 CA ? N/A Q03692 11839302
    15719 1gr7:A (1.8) BS01 CU ? GO:0005507 ... P00282 12007613
    15720 1gr7:B (1.8) BS01 CU ? GO:0005507 ... P00282 12007613
    15721 1gr7:C (1.8) BS01 CU ? GO:0005507 ... P00282 12007613
    15722 1gr7:D (1.8) BS01 CU ? GO:0005507 ... P00282 12007613
    15723 1gra:A (2.0) BS01 FAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15724 1gra:A (2.0) BS02 NDP 1.8.1.7 GO:0004362 ... P00390 2585516
    15725 1gra:A (2.0) BS03 GSH 1.8.1.7 GO:0004362 ... P00390 2585516
    15726 1gra:A (2.0) BS04 GSH 1.8.1.7 GO:0004362 ... P00390 2585516
    15727 1grb:A (1.85) BS01 PO4 1.8.1.7 GO:0004362 ... P00390 2585516
    15728 1grb:A (1.85) BS02 FAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15729 1grb:A (1.85) BS03 NAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15730 1grb:A (1.85) BS04 NDP 1.8.1.7 GO:0004362 ... P00390 2585516
    15731 1gre:A (2.0) BS01 PO4 1.8.1.7 GO:0004362 ... P00390 2585516
    15732 1gre:A (2.0) BS02 FAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15733 1gre:A (2.0) BS03 GSH 1.8.1.7 GO:0004362 ... P00390 2585516
    15734 1grf:A (2.0) BS01 PO4 1.8.1.7 GO:0004362 ... P00390 2585516
    15735 1grf:A (2.0) BS02 FAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15736 1grg:A (2.0) BS01 PO4 1.8.1.7 GO:0004362 ... P00390 2585516
    15737 1grg:A (2.0) BS02 FAD 1.8.1.7 GO:0004362 ... P00390 2585516
    15738 1grh:A (3.0) BS01 FAD 1.8.1.7 GO:0004362 ... P00390 3338461
    15739 1grn:A (2.1) BS01 MG 3.6.5.2 GO:0000139 ... P60953 9846874
    15740 1grn:A (2.1) BS02 GDP 3.6.5.2 GO:0000139 ... P60953 9846874
    15741 1grn:A (2.1) BS03 AF3 3.6.5.2 GO:0000139 ... P60953 9846874
    15742 1gro:A (2.5) BS01 MG 1.1.1.42 GO:0000287 ... P08200 8745407
    15743 1grp:A (2.5) BS01 MG 1.1.1.42 GO:0000287 ... P08200 8745407
    15744 1grq:A (2.9) BS01 CLK 2.7.1.- GO:0005524 ... Q56148 11468347
    15745 1grr:A (2.9) BS01 CLC 2.7.1.- GO:0005524 ... Q56148 11468347
    15746 1grt:A (2.3) BS01 FAD 1.8.1.7 GO:0004362 ... P00390 9174360
    15747 1grv:A (2.9) BS01 MG 2.4.2.8 GO:0000166 ... P0A9M2 12070315
    15748 1grv:B (2.9) BS01 MG 2.4.2.8 GO:0000166 ... P0A9M2 12070315
    15749 1grx:A (-1.00) BS01 GSH ? GO:0000166 ... P68688 1304339
    15750 1gs3:A (2.1) BS01 EQU 5.3.3.1 GO:0004769 ... P07445 N/A
    15751 1gs4:A (1.95) BS01 ZK5 ? N/A P10275 11906285
    15752 1gs5:A (1.5) BS01 NLG 2.7.2.8 GO:0003991 ... P0A6C8 12005432
    15753 1gs5:A (1.5) BS02 ANP 2.7.2.8 GO:0003991 ... P0A6C8 12005432
    15754 1gs6:X (2.2) BS01 CU 1.7.2.1 GO:0005507 ... O68601 11829502
    15755 1gs6:X (2.2) BS02 CU 1.7.2.1 GO:0005507 ... O68601 11829502
    15756 1gs6:X (2.2) BS03 MG 1.7.2.1 GO:0005507 ... O68601 11829502
    15757 1gs7:A (1.85) BS01 CU 1.7.2.1 GO:0005507 ... O68601 11829502
    15758 1gs7:A (1.85) BS02 ZN 1.7.2.1 GO:0005507 ... O68601 11829502
    15759 1gs7:A (1.85) BS03 ZN 1.7.2.1 GO:0005507 ... O68601 11829502
    15760 1gs8:A (1.9) BS01 CU 1.7.2.1 GO:0005507 ... O68601 11829502
    15761 1gs8:A (1.9) BS02 CU 1.7.2.1 GO:0005507 ... O68601 11829502
    15762 1gs8:A (1.9) BS03 ZN 1.7.2.1 GO:0005507 ... O68601 11829502
    15763 1gs8:A (1.9) BS04 ZN 1.7.2.1 GO:0005507 ... O68601 11829502
    15764 1gsa:A (2.0) BS01 MG 6.3.2.3 GO:0000287 ... P04425 8810901
    15765 1gsa:A (2.0) BS02 MG 6.3.2.3 GO:0000287 ... P04425 8810901
    15766 1gsa:A (2.0) BS03 SO4 6.3.2.3 GO:0000287 ... P04425 8810901
    15767 1gsa:A (2.0) BS04 ADP 6.3.2.3 GO:0000287 ... P04425 8810901
    15768 1gsa:A (2.0) BS05 GSH 6.3.2.3 GO:0000287 ... P04425 8810901
    15769 1gse:A (2.0) BS01 GSH 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048
    15770 1gse:A (2.0) BS02 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    15771 1gse:A (2.0) BS03 GSH 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048
    15772 1gse:B (2.0) BS01 GSH 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048
    15773 1gse:B (2.0) BS02 GSH 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048
    15774 1gse:B (2.0) BS03 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    15775 1gsf:A (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 PDBbind: -logKd/Ki=5.00, IC50~10uM
    BindingDB: IC50=5000nM
    15776 1gsf:B (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    15777 1gsf:C (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    15778 1gsf:D (2.7) BS01 EAA 1.11.1.-
    2.5.1.18
    5.3.3.-
    GO:0004364 ... P08263 8591048 BindingDB: IC50=5000nM
    15779 1gsi:A (1.6) BS01 MG 2.7.4.9 GO:0000287 ... P9WKE1 11914484
    15780 1gsi:A (1.6) BS02 TMP 2.7.4.9 GO:0000287 ... P9WKE1 11914484
    15781 1gsj:A (1.85) BS01 NLG 2.7.2.8 GO:0003991 ... P0A6C8 12005432
    15782 1gsj:A (1.85) BS02 ANP 2.7.2.8 GO:0003991 ... P0A6C8 12005432
    15783 1gsk:A (1.7) BS01 CU 1.10.3.2
    1.3.3.5
    GO:0005507 ... P07788 12637519
    15784 1gsl:A (2.0) BS01 GAL ? GO:0030246 ... P24146 8478943
    15785 1gsl:A (2.0) BS02 FUC ? GO:0030246 ... P24146 8478943
    15786 1gsl:A (2.0) BS03 FUC ? GO:0030246 ... P24146 8478943
    15787 1gsl:A (2.0) BS04 FUC ? GO:0030246 ... P24146 8478943
    15788 1gsl:A (2.0) BS05 MN ? GO:0030246 ... P24146 8478943
    15789 1gsl:A (2.0) BS06 CA ? GO:0030246 ... P24146 8478943
    15790 1gsn:A (1.7) BS01 FAD 1.8.1.7 GO:0004362 ... P00390 9546215
    15791 1gsn:A (1.7) BS02 GSH 1.8.1.7 GO:0004362 ... P00390 9546215
    15792 1gsp:A (2.2) BS01 SGP 4.6.1.24 GO:0001411 ... P00651 9546218
    15793 1gsq:A (2.4) BS01 GDN 2.5.1.18 GO:0004364 ... P46088 7727393
    15794 1gss:A (2.8) BS01 LEE 2.5.1.18 GO:0000302 ... P09211 1522586 BindingDB: Ki=10000nM, IC50=1.31e+5nM
    15795 1gss:B (2.8) BS01 LEE 2.5.1.18 GO:0000302 ... P09211 1522586 BindingDB: Ki=10000nM, IC50=1.31e+5nM
    15796 1gsu:A (1.94) BS01 GTX 2.5.1.18 GO:0004364 ... P20136 9571047
    15797 1gsu:B (1.94) BS01 GTX 2.5.1.18 GO:0004364 ... P20136 9571047
    15798 1gsy:A (2.44) BS01 GSH 2.5.1.18 GO:0000302 ... P19157 9677344
    15799 1gsy:B (2.44) BS01 GSH 2.5.1.18 GO:0000302 ... P19157 9677344
    15800 1gsz:A (2.8) BS01 R71 4.2.1.129
    5.4.99.17
    GO:0005811 ... P33247 12031670 PDBbind: -logKd/Ki=7.21, IC50=61nM

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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