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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    44401 1r3s:A (1.65) BS01 1CP 4.1.1.37 GO:0004853 ... P06132 14633982
    44402 1r3t:A (1.7) BS01 CP3 4.1.1.37 GO:0004853 ... P06132 14633982
    44403 1r3u:A (2.5) BS01 MG 2.4.2.8 GO:0000166 ... Q8R7L0 N/A
    44404 1r3u:B (2.5) BS01 MG 2.4.2.8 GO:0000166 ... Q8R7L0 N/A
    44405 1r3v:A (1.9) BS01 1CP 4.1.1.37 GO:0004853 ... P06132 14633982
    44406 1r3w:A (1.7) BS01 CP3 4.1.1.37 GO:0004853 ... P06132 14633982
    44407 1r3y:A (1.755) BS01 CP3 4.1.1.37 GO:0004853 ... P06132 14633982
    44408 1r42:A (2.2) BS01 ZN 3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 14754895
    44409 1r43:A (2.8) BS01 ZN 3.5.1.6 GO:0003837 ... Q96W94 14534321
    44410 1r43:A (2.8) BS02 ZN 3.5.1.6 GO:0003837 ... Q96W94 14534321
    44411 1r43:B (2.8) BS01 ZN 3.5.1.6 GO:0003837 ... Q96W94 14534321
    44412 1r43:B (2.8) BS02 ZN 3.5.1.6 GO:0003837 ... Q96W94 14534321
    44413 1r43:B (2.8) BS03 BIB 3.5.1.6 GO:0003837 ... Q96W94 14534321
    44414 1r44:A (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44415 1r44:B (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44416 1r44:C (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44417 1r44:D (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44418 1r44:E (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44419 1r44:F (2.25) BS01 ZN 3.4.13.22 GO:0006508 ... Q06241 9702193
    44420 1r47:A (3.45) BS01 GAL 3.2.1.22 GO:0003824 ... P06280 15003450
    44421 1r47:B (3.45) BS01 GAL 3.2.1.22 GO:0003824 ... P06280 15003450
    44422 1r49:A (3.13) BS01 dna 5.6.2.1 GO:0003677 ... P11387 14594810
    44423 1r49:A (3.13) BS02 dna 5.6.2.1 GO:0003677 ... P11387 14594810
    44424 1r4a:A (2.3) BS01 MG ? GO:0000139 ... P61212 14718928
    44425 1r4a:A (2.3) BS02 GNP ? GO:0000139 ... P61212 14718928
    44426 1r4a:B (2.3) BS01 MG ? GO:0000139 ... P61212 14718928
    44427 1r4a:B (2.3) BS02 GNP ? GO:0000139 ... P61212 14718928
    44428 1r4a:C (2.3) BS01 MG ? GO:0000139 ... P61212 14718928
    44429 1r4a:C (2.3) BS02 GNP ? GO:0000139 ... P61212 14718928
    44430 1r4a:D (2.3) BS01 MG ? GO:0000139 ... P61212 14718928
    44431 1r4a:D (2.3) BS02 GNP ? GO:0000139 ... P61212 14718928
    44432 1r4f:A (2.3) BS01 CA 3.2.2.1 GO:0006139 ... Q9GPQ4 15050818
    44433 1r4f:B (2.3) BS01 CA 3.2.2.1 GO:0006139 ... Q9GPQ4 15050818
    44434 1r4f:B (2.3) BS02 AD3 3.2.2.1 GO:0006139 ... Q9GPQ4 15050818
    44435 1r4i:A (3.1) BS01 dna ? GO:0003700 ... P15207 15037741
    44436 1r4i:A (3.1) BS02 dna ? GO:0003700 ... P15207 15037741
    44437 1r4i:A (3.1) BS03 ZN ? GO:0003700 ... P15207 15037741
    44438 1r4i:A (3.1) BS04 ZN ? GO:0003700 ... P15207 15037741
    44439 1r4i:B (3.1) BS01 dna ? GO:0003700 ... P15207 15037741
    44440 1r4i:B (3.1) BS02 dna ? GO:0003700 ... P15207 15037741
    44441 1r4i:B (3.1) BS03 ZN ? GO:0003700 ... P15207 15037741
    44442 1r4i:B (3.1) BS04 ZN ? GO:0003700 ... P15207 15037741
    44443 1r4l:A (3.0) BS01 ZN 3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 14754895
    44444 1r4l:A (3.0) BS02 XX5 3.4.17.-
    3.4.17.23
    GO:0006508 ... Q9BYF1 14754895 BindingDB: IC50=0.44nM
    44445 1r4m:F (3.0) BS01 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44446 1r4m:H (3.0) BS01 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44447 1r4n:B (3.6) BS01 ATP 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44448 1r4n:D (3.6) BS01 ATP 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44449 1r4n:F (3.6) BS01 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44450 1r4n:F (3.6) BS02 ATP 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44451 1r4n:H (3.6) BS01 ZN 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44452 1r4n:H (3.6) BS02 ATP 6.2.1.64 GO:0000278 ... Q8TBC4 14690597
    44453 1r4o:A (2.5) BS01 dna ? GO:0003700 ... P06536 1865905
    44454 1r4o:A (2.5) BS02 dna ? GO:0003700 ... P06536 1865905
    44455 1r4o:A (2.5) BS03 ZN ? GO:0003700 ... P06536 1865905
    44456 1r4o:A (2.5) BS04 ZN ? GO:0003700 ... P06536 1865905
    44457 1r4o:B (2.5) BS01 dna ? GO:0003700 ... P06536 1865905
    44458 1r4o:B (2.5) BS02 ZN ? GO:0003700 ... P06536 1865905
    44459 1r4o:B (2.5) BS03 ZN ? GO:0003700 ... P06536 1865905
    44460 1r4p:A (1.77) BS01 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44461 1r4p:A (1.77) BS02 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44462 1r4p:A (1.77) BS03 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44463 1r4p:A (1.77) BS04 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44464 1r4p:A (1.77) BS05 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44465 1r4p:A (1.77) BS06 FMT 3.2.2.22 GO:0005576 ... P09385 15075327
    44466 1r4p:B (1.77) BS01 1PS ? GO:0005576 ... P09386 15075327
    44467 1r4p:C (1.77) BS01 FMT ? GO:0005576 ... P09386 15075327
    44468 1r4p:C (1.77) BS02 1PS ? GO:0005576 ... P09386 15075327
    44469 1r4p:C (1.77) BS03 FMT ? GO:0005576 ... P09386 15075327
    44470 1r4p:D (1.77) BS01 1PS ? GO:0005576 ... P09386 15075327
    44471 1r4p:D (1.77) BS02 FMT ? GO:0005576 ... P09386 15075327
    44472 1r4p:E (1.77) BS01 FMT ? GO:0005576 ... P09386 15075327
    44473 1r4p:E (1.77) BS02 FMT ? GO:0005576 ... P09386 15075327
    44474 1r4p:F (1.77) BS01 1PS ? GO:0005576 ... P09386 15075327
    44475 1r4p:F (1.77) BS02 FMT ? GO:0005576 ... P09386 15075327
    44476 1r4r:A (3.0) BS01 dna ? GO:0003700 ... P06536 1865905
    44477 1r4r:A (3.0) BS02 dna ? GO:0003700 ... P06536 1865905
    44478 1r4r:A (3.0) BS03 ZN ? GO:0003700 ... P06536 1865905
    44479 1r4r:A (3.0) BS04 ZN ? GO:0003700 ... P06536 1865905
    44480 1r4r:B (3.0) BS01 dna ? GO:0003700 ... P06536 1865905
    44481 1r4r:B (3.0) BS02 dna ? GO:0003700 ... P06536 1865905
    44482 1r4r:B (3.0) BS03 ZN ? GO:0003700 ... P06536 1865905
    44483 1r4r:B (3.0) BS04 ZN ? GO:0003700 ... P06536 1865905
    44484 1r4s:A (1.8) BS01 CYS 1.7.3.3 GO:0004846 ... Q00511 14993669
    44485 1r4s:A (1.8) BS02 MUA 1.7.3.3 GO:0004846 ... Q00511 14993669
    44486 1r4u:A (1.65) BS01 OXC 1.7.3.3 GO:0004846 ... Q00511 14993669
    44487 1r4v:A (1.9) BS01 ZN ? GO:0046982 ... O66665 16287087
    44488 1r4v:A (1.9) BS02 ZN ? GO:0046982 ... O66665 16287087
    44489 1r4w:A (2.5) BS01 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    PDBbind: -logKd/Ki=4.05, Kd=90uM
    44490 1r4w:B (2.5) BS01 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    PDBbind: -logKd/Ki=4.05, Kd=90uM
    44491 1r4w:C (2.5) BS01 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    44492 1r4w:C (2.5) BS02 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    44493 1r4w:D (2.5) BS01 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    44494 1r4w:D (2.5) BS02 GSH 2.5.1.18 GO:0004364 ... P24473 14717589 MOAD: Kd=90uM
    44495 1r4z:A (1.8) BS01 RIL 3.1.1.3 GO:0004806 ... P37957 16342303
    44496 1r4z:B (1.8) BS01 RIL 3.1.1.3 GO:0004806 ... P37957 16342303
    44497 1r50:A (1.45) BS01 SIL 3.1.1.3 GO:0004806 ... P37957 16342303
    44498 1r50:B (1.45) BS01 SIL 3.1.1.3 GO:0004806 ... P37957 16342303
    44499 1r51:A (1.75) BS01 AZA 1.7.3.3 GO:0004846 ... Q00511 14993669
    44500 1r54:A (1.85) BS01 ZN 3.4.24.- GO:0004222 ... Q9BZ11 14659745
    44501 1r54:A (1.85) BS02 CA 3.4.24.- GO:0004222 ... Q9BZ11 14659745
    44502 1r55:A (1.58) BS01 ZN 3.4.24.- GO:0004222 ... Q9BZ11 14659745
    44503 1r55:A (1.58) BS02 CA 3.4.24.- GO:0004222 ... Q9BZ11 14659745
    44504 1r55:A (1.58) BS03 097 3.4.24.- GO:0004222 ... Q9BZ11 14659745
    44505 1r58:A (1.9) BS01 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44506 1r58:A (1.9) BS02 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44507 1r58:A (1.9) BS03 AO5 3.4.11.18 GO:0006508 ... P50579 15012983 PDBbind: -logKd/Ki=6.96, IC50=0.11uM
    BindingDB: IC50=110nM
    44508 1r5a:A (2.5) BS01 CU 2.5.1.18 GO:0004364 ... Q9GQG7 15717864
    44509 1r5a:A (2.5) BS02 GTS 2.5.1.18 GO:0004364 ... Q9GQG7 15717864
    44510 1r5c:A (2.1) BS01 CPA 4.6.1.18 GO:0003676 ... P00669 15048772
    44511 1r5c:B (2.1) BS01 CPA 4.6.1.18 GO:0003676 ... P00669 15048772
    44512 1r5g:A (2.0) BS01 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44513 1r5g:A (2.0) BS02 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44514 1r5g:A (2.0) BS03 AO1 3.4.11.18 GO:0006508 ... P50579 15012983 PDBbind: -logKd/Ki=7.52, IC50=0.03uM
    BindingDB: IC50=22nM
    44515 1r5h:A (2.4) BS01 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44516 1r5h:A (2.4) BS02 MN 3.4.11.18 GO:0006508 ... P50579 15012983
    44517 1r5h:A (2.4) BS03 AO2 3.4.11.18 GO:0006508 ... P50579 15012983 MOAD: ic50=0.17uM
    PDBbind: -logKd/Ki=6.74, IC50=0.18uM
    BindingDB: IC50=170nM
    44518 1r5i:A (2.6) BS01 peptide ? GO:0006955 ... P01903 14962388
    44519 1r5i:B (2.6) BS01 peptide ? GO:0006955 ... P01911 14962388
    44520 1r5i:D (2.6) BS01 peptide ? N/A Q48898 14962388
    44521 1r5i:E (2.6) BS01 peptide ? GO:0006955 ... P01903 14962388
    44522 1r5i:F (2.6) BS01 peptide ? GO:0006955 ... P01911 14962388
    44523 1r5i:H (2.6) BS01 peptide ? N/A Q48898 14962388
    44524 1r5k:A (2.7) BS01 GW5 ? N/A P03372 15893725 BindingDB: EC50=390nM, IC50=>1270nM
    44525 1r5k:B (2.7) BS01 GW5 ? N/A P03372 15893725 BindingDB: EC50=390nM, IC50=>1270nM
    44526 1r5k:C (2.7) BS01 GW5 ? N/A P03372 15893725 BindingDB: EC50=390nM, IC50=>1270nM
    44527 1r5l:A (1.5) BS01 VIV ? GO:0001890 ... P49638 14657365 BindingDB: Kd=2.4nM
    44528 1r5n:A (2.9) BS01 GDP 3.6.5.- GO:0000288 ... O74718 15099522 PDBbind: -logKd/Ki=5.42, Kd=3.8uM
    44529 1r5o:A (3.2) BS01 GNP 3.6.5.- GO:0000288 ... O74718 15099522
    44530 1r5t:A (2.0) BS01 ZN 3.5.4.5 GO:0003824 ... Q06549 15148397
    44531 1r5t:B (2.0) BS01 ZN 3.5.4.5 GO:0003824 ... Q06549 15148397
    44532 1r5t:C (2.0) BS01 ZN 3.5.4.5 GO:0003824 ... Q06549 15148397
    44533 1r5t:D (2.0) BS01 ZN 3.5.4.5 GO:0003824 ... Q06549 15148397
    44534 1r5u:A (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P04050 14963322
    44535 1r5u:A (4.5) BS02 MG 2.7.7.6 GO:0000428 ... P04050 14963322
    44536 1r5u:B (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P08518 14963322
    44537 1r5u:C (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P16370 14963322
    44538 1r5u:I (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P27999 14963322
    44539 1r5u:I (4.5) BS02 ZN 2.7.7.6 GO:0000428 ... P27999 14963322
    44540 1r5u:J (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P22139 14963322
    44541 1r5u:L (4.5) BS01 ZN 2.7.7.6 GO:0000428 ... P40422 14963322
    44542 1r5v:A (2.5) BS01 peptide ? GO:0006955 ... P04224 14690592
    44543 1r5v:B (2.5) BS01 peptide ? GO:0006955 ... P18468 14690592
    44544 1r5v:C (2.5) BS01 peptide ? GO:0006955 ... P04224 14690592
    44545 1r5v:D (2.5) BS01 peptide ? GO:0006955 ... P18468 14690592
    44546 1r5w:A (2.9) BS01 peptide ? GO:0006955 ... P04224 14690592
    44547 1r5w:A (2.9) BS02 peptide ? GO:0006955 ... P04224 14690592
    44548 1r5w:B (2.9) BS01 peptide ? GO:0006955 ... Q31164 14690592
    44549 1r5w:C (2.9) BS01 peptide ? GO:0006955 ... P04224 14690592
    44550 1r5w:C (2.9) BS02 peptide ? GO:0006955 ... P04224 14690592
    44551 1r5w:D (2.9) BS01 peptide ? GO:0006955 ... Q31164 14690592
    44552 1r5x:A (2.3) BS01 ZN ? GO:0006508 ... O28085 14737182
    44553 1r5x:B (2.3) BS01 ZN ? GO:0006508 ... O28085 14737182
    44554 1r5y:A (1.2) BS01 ZN 2.4.2.29 GO:0002099 ... P28720 15050823
    44555 1r5y:A (1.2) BS02 DQU 2.4.2.29 GO:0002099 ... P28720 15050823 MOAD: Ki=0.35uM
    PDBbind: -logKd/Ki=6.46, Ki=0.35uM
    44556 1r61:A (2.5) BS01 ZN ? GO:0004061 ... P84132 N/A
    44557 1r61:B (2.5) BS01 ZN ? GO:0004061 ... P84132 N/A
    44558 1r64:A (2.2) BS01 peptide 3.4.21.61 GO:0004252 ... P13134 14992578
    44559 1r64:A (2.2) BS02 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44560 1r64:A (2.2) BS03 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44561 1r64:A (2.2) BS04 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44562 1r64:A (2.2) BS05 K 3.4.21.61 GO:0004252 ... P13134 14992578
    44563 1r64:A (2.2) BS06 K 3.4.21.61 GO:0004252 ... P13134 14992578
    44564 1r64:B (2.2) BS01 peptide 3.4.21.61 GO:0004252 ... P13134 14992578
    44565 1r64:B (2.2) BS02 K 3.4.21.61 GO:0004252 ... P13134 14992578
    44566 1r64:B (2.2) BS03 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44567 1r64:B (2.2) BS04 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44568 1r64:B (2.2) BS05 CA 3.4.21.61 GO:0004252 ... P13134 14992578
    44569 1r64:B (2.2) BS06 K 3.4.21.61 GO:0004252 ... P13134 14992578
    44570 1r64:B (2.2) BS07 K 3.4.21.61 GO:0004252 ... P13134 14992578
    44571 1r65:A (1.95) BS01 FE2 1.17.4.1 GO:0004748 ... P69924 14677973
    44572 1r65:A (1.95) BS02 FE2 1.17.4.1 GO:0004748 ... P69924 14677973
    44573 1r65:B (1.95) BS01 FE2 1.17.4.1 GO:0004748 ... P69924 14677973
    44574 1r65:B (1.95) BS02 FE2 1.17.4.1 GO:0004748 ... P69924 14677973
    44575 1r66:A (1.44) BS01 NAD 4.2.1.46 GO:0000166 ... Q9ZGH3 14570895
    44576 1r66:A (1.44) BS02 TYD 4.2.1.46 GO:0000166 ... Q9ZGH3 14570895
    44577 1r67:A (1.77) BS01 MG 5.3.3.2 GO:0000287 ... Q46822 16617181
    44578 1r6a:A (2.6) BS01 SAH 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13
    GO:0003968 ... P12823 15152003
    44579 1r6a:A (2.6) BS02 RVP 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13
    GO:0003968 ... P12823 15152003
    44580 1r6b:X (2.25) BS01 MG ? GO:0004176 ... P0ABH9 15037248
    44581 1r6b:X (2.25) BS02 ADP ? GO:0004176 ... P0ABH9 15037248
    44582 1r6b:X (2.25) BS03 ADP ? GO:0004176 ... P0ABH9 15037248
    44583 1r6d:A (1.35) BS01 NAD 4.2.1.46 GO:0000166 ... Q9ZGH3 14570895
    44584 1r6d:A (1.35) BS02 DAU 4.2.1.46 GO:0000166 ... Q9ZGH3 14570895
    44585 1r6g:A (3.0) BS01 442 ? GO:0003677 ... P10828 15177471 PDBbind: -logKd/Ki=9.21, IC50=0.62nM
    44586 1r6m:A (2.0) BS01 PO4 2.7.7.56 GO:0000049 ... P50597 14573594
    44587 1r6n:A (2.4) BS01 434 ? GO:0006275 ... P04015 14634007 MOAD: Kd=40nM
    PDBbind: -logKd/Ki=7.40, Kd=40nM
    44588 1r6n:A (2.4) BS02 434 ? GO:0006275 ... P04015 14634007 MOAD: Kd=40nM
    PDBbind: -logKd/Ki=7.40, Kd=40nM
    44589 1r6n:A (2.4) BS03 ALQ ? GO:0006275 ... P04015 14634007
    44590 1r6o:A (2.25) BS01 ZN ? N/A P0ABH9 15037248
    44591 1r6o:A (2.25) BS02 YBT ? N/A P0ABH9 15037248
    44592 1r6o:B (2.25) BS01 ZN ? N/A P0ABH9 15037248
    44593 1r6o:B (2.25) BS02 YBT ? N/A P0ABH9 15037248
    44594 1r6o:B (2.25) BS03 YBT ? N/A P0ABH9 15037248
    44595 1r6o:D (2.25) BS01 YBT ? GO:0005515 ... P0A8Q6 15037248
    44596 1r6p:A (-1.00) BS01 CA ? GO:0005509 ... Q7ZZB9 15109253
    44597 1r6q:A (2.35) BS01 YBT ? N/A P0ABH9 15037248
    44598 1r6q:B (2.35) BS01 YBT ? N/A P0ABH9 15037248
    44599 1r6q:B (2.35) BS02 YBT ? N/A P0ABH9 15037248
    44600 1r6q:D (2.35) BS01 YBT ? GO:0005515 ... P0A8Q6 15037248

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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