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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    42001 1q82:Q (2.98) BS01 rna ? GO:0003723 ... P14119 12185246
    42002 1q82:R (2.98) BS01 rna ? GO:0003735 ... P12734 12185246
    42003 1q82:R (2.98) BS02 rna ? GO:0003735 ... P12734 12185246
    42004 1q82:S (2.98) BS01 rna ? GO:0002181 ... P10970 12185246
    42005 1q82:T (2.98) BS01 rna ? GO:0000027 ... P12732 12185246
    42006 1q82:U (2.98) BS01 rna ? GO:0002181 ... P10972 12185246
    42007 1q82:U (2.98) BS02 MG ? GO:0002181 ... P10972 12185246
    42008 1q82:V (2.98) BS01 rna ? GO:0003735 ... P14116 12185246
    42009 1q82:W (2.98) BS01 rna ? GO:0003735 ... P10971 12185246
    42010 1q82:X (2.98) BS01 rna ? GO:0000463 ... P14121 12185246
    42011 1q82:X (2.98) BS02 rna ? GO:0000463 ... P14121 12185246
    42012 1q82:Y (2.98) BS01 rna ? GO:0002181 ... P18138 12185246
    42013 1q82:Z (2.98) BS01 rna ? GO:0000166 ... P12736 12185246
    42014 1q82:Z (2.98) BS02 MG ? GO:0000166 ... P12736 12185246
    42015 1q83:A (2.65) BS01 TZ5 3.1.1.7 GO:0004104 ... P21836 14757816 PDBbind: -logKd/Ki=12.39, Ki=410fM
    BindingDB: Ki=0.410nM, Kd=0.00041nM
    42016 1q83:B (2.65) BS01 TZ5 3.1.1.7 GO:0004104 ... P21836 14757816 BindingDB: Ki=0.410nM, Kd=0.00041nM
    42017 1q84:A (2.45) BS01 TZ4 3.1.1.7 GO:0004104 ... P21836 14757816 MOAD: Ki=8900fM
    PDBbind: -logKd/Ki=11.05, Ki=8900fM
    42018 1q84:B (2.45) BS01 TZ4 3.1.1.7 GO:0004104 ... P21836 14757816 MOAD: Ki=8900fM
    42019 1q86:1 (3.0) BS01 rna ? GO:0003735 ... P60619 12185246
    42020 1q86:2 (3.0) BS01 rna ? GO:0003723 ... P32410 12185246
    42021 1q86:3 (3.0) BS01 rna ? GO:0003735 ... P22452 12185246
    42022 1q86:4 (3.0) BS01 rna ? GO:0000049 ... P32411 12185246
    42023 1q86:4 (3.0) BS02 MG ? GO:0000049 ... P32411 12185246
    42024 1q86:C (3.0) BS01 rna ? GO:0002181 ... P20276 12185246
    42025 1q86:C (3.0) BS02 MG ? GO:0002181 ... P20276 12185246
    42026 1q86:D (3.0) BS01 rna ? GO:0003723 ... P20279 12185246
    42027 1q86:E (3.0) BS01 rna ? GO:0003723 ... P12735 12185246
    42028 1q86:F (3.0) BS01 rna ? GO:0000049 ... P14124 12185246
    42029 1q86:F (3.0) BS02 rna ? GO:0000049 ... P14124 12185246
    42030 1q86:G (3.0) BS01 rna ? GO:0002181 ... P14135 12185246
    42031 1q86:H (3.0) BS01 rna ? GO:0001682 ... P12743 12185246
    42032 1q86:J (3.0) BS01 rna ? GO:0000027 ... P60617 12185246
    42033 1q86:K (3.0) BS01 rna ? GO:0003729 ... P29198 12185246
    42034 1q86:L (3.0) BS01 rna ? GO:0003735 ... P22450 12185246
    42035 1q86:M (3.0) BS01 rna ? GO:0003735 ... P12737 12185246
    42036 1q86:N (3.0) BS01 rna ? GO:0002181 ... P60618 12185246
    42037 1q86:O (3.0) BS01 rna ? GO:0000027 ... P14123 12185246
    42038 1q86:O (3.0) BS02 rna ? GO:0000027 ... P14123 12185246
    42039 1q86:P (3.0) BS01 rna ? GO:0003723 ... P12733 12185246
    42040 1q86:Q (3.0) BS01 rna ? GO:0003723 ... P14119 12185246
    42041 1q86:R (3.0) BS01 rna ? GO:0003735 ... P12734 12185246
    42042 1q86:R (3.0) BS02 rna ? GO:0003735 ... P12734 12185246
    42043 1q86:S (3.0) BS01 rna ? GO:0002181 ... P10970 12185246
    42044 1q86:T (3.0) BS01 rna ? GO:0000027 ... P12732 12185246
    42045 1q86:U (3.0) BS01 rna ? GO:0002181 ... P10972 12185246
    42046 1q86:U (3.0) BS02 MG ? GO:0002181 ... P10972 12185246
    42047 1q86:V (3.0) BS01 rna ? GO:0003735 ... P14116 12185246
    42048 1q86:W (3.0) BS01 rna ? GO:0003735 ... P10971 12185246
    42049 1q86:X (3.0) BS01 rna ? GO:0000463 ... P14121 12185246
    42050 1q86:X (3.0) BS02 rna ? GO:0000463 ... P14121 12185246
    42051 1q86:Y (3.0) BS01 rna ? GO:0002181 ... P18138 12185246
    42052 1q86:Z (3.0) BS01 rna ? GO:0000166 ... P12736 12185246
    42053 1q86:Z (3.0) BS02 MG ? GO:0000166 ... P12736 12185246
    42054 1q8f:A (1.7) BS01 CA 3.2.2.8 GO:0005509 ... P33022 15130467
    42055 1q8f:B (1.7) BS01 CA 3.2.2.8 GO:0005509 ... P33022 15130467
    42056 1q8f:C (1.7) BS01 CA 3.2.2.8 GO:0005509 ... P33022 15130467
    42057 1q8f:D (1.7) BS01 CA 3.2.2.8 GO:0005509 ... P33022 15130467
    42058 1q8h:A (2.0) BS01 CA ? GO:0001649 ... Q8HYY9 14586470
    42059 1q8h:A (2.0) BS02 CA ? GO:0001649 ... Q8HYY9 14586470
    42060 1q8j:A (1.9) BS01 C2F 2.1.1.13 GO:0042558 ... Q9WYA5 14752199
    42061 1q8j:B (1.9) BS01 C2F 2.1.1.13 GO:0042558 ... Q9WYA5 14752199
    42062 1q8m:A (2.6) BS01 GSH ? N/A Q9NP99 14656437
    42063 1q8o:A (2.2) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42064 1q8o:A (2.2) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42065 1q8o:A (2.2) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42066 1q8o:A (2.2) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42067 1q8o:B (2.2) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42068 1q8o:B (2.2) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42069 1q8o:B (2.2) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42070 1q8o:B (2.2) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42071 1q8p:A (1.75) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42072 1q8p:A (1.75) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42073 1q8p:A (1.75) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42074 1q8p:A (1.75) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42075 1q8p:B (1.75) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42076 1q8p:B (1.75) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42077 1q8p:B (1.75) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42078 1q8p:B (1.75) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42079 1q8q:A (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42080 1q8q:A (2.05) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42081 1q8q:A (2.05) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42082 1q8q:A (2.05) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42083 1q8q:B (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42084 1q8q:B (2.05) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42085 1q8q:B (2.05) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42086 1q8q:B (2.05) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42087 1q8s:A (2.05) BS01 MAN ? GO:0030246 ... Q8GSD2 14729339
    42088 1q8s:A (2.05) BS02 MN ? GO:0030246 ... Q8GSD2 14729339
    42089 1q8s:A (2.05) BS03 CA ? GO:0030246 ... Q8GSD2 14729339
    42090 1q8s:B (2.05) BS01 MMA ? GO:0030246 ... Q8GSD2 14729339
    42091 1q8s:B (2.05) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42092 1q8s:B (2.05) BS03 MN ? GO:0030246 ... Q8GSD2 14729339
    42093 1q8s:B (2.05) BS04 CA ? GO:0030246 ... Q8GSD2 14729339
    42094 1q8t:A (2.0) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 14656443
    42095 1q8t:A (2.0) BS02 Y27 2.7.11.11 GO:0001669 ... P00517 14656443 MOAD: Kd=17.5uM
    PDBbind: -logKd/Ki=4.76, Kd=17.5uM
    BindingDB: IC50=42000nM
    42096 1q8u:A (1.9) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 14656443
    42097 1q8u:A (1.9) BS02 H52 2.7.11.11 GO:0001669 ... P00517 14656443 MOAD: Kd=1.1uM
    PDBbind: -logKd/Ki=5.96, Kd=1.1uM
    BindingDB: IC50=394nM
    42098 1q8u:A (1.9) BS03 H52 2.7.11.11 GO:0001669 ... P00517 14656443 MOAD: Kd=1.1uM
    PDBbind: -logKd/Ki=5.96, Kd=1.1uM
    BindingDB: IC50=394nM
    42099 1q8v:A (1.85) BS01 MAN ? GO:0030246 ... Q8GSD2 14729339
    42100 1q8v:A (1.85) BS02 MN ? GO:0030246 ... Q8GSD2 14729339
    42101 1q8v:A (1.85) BS03 CA ? GO:0030246 ... Q8GSD2 14729339
    42102 1q8v:B (1.85) BS01 MAN ? GO:0030246 ... Q8GSD2 14729339
    42103 1q8v:B (1.85) BS02 MAN ? GO:0030246 ... Q8GSD2 14729339
    42104 1q8v:B (1.85) BS03 MAN ? GO:0030246 ... Q8GSD2 14729339
    42105 1q8v:B (1.85) BS04 MN ? GO:0030246 ... Q8GSD2 14729339
    42106 1q8v:B (1.85) BS05 CA ? GO:0030246 ... Q8GSD2 14729339
    42107 1q8w:A (2.2) BS01 peptide 2.7.11.11 GO:0001669 ... P00517 14656443
    42108 1q8w:A (2.2) BS02 M77 2.7.11.11 GO:0001669 ... P00517 14656443 MOAD: Kd=5.7uM
    PDBbind: -logKd/Ki=5.24, Kd=5.7uM
    BindingDB: IC50=1494nM
    42109 1q8y:A (2.05) BS01 MG 2.7.11.1 GO:0004672 ... Q03656 12911299
    42110 1q8y:A (2.05) BS02 ADP 2.7.11.1 GO:0004672 ... Q03656 12911299
    42111 1q8y:B (2.05) BS01 ADE 2.7.11.1 GO:0004672 ... Q03656 12911299
    42112 1q90:A (3.1) BS01 HEC ? GO:0005506 ... P23577 14647374
    42113 1q90:B (3.1) BS01 HEC ? GO:0009055 ... Q00471 14647374
    42114 1q90:B (3.1) BS02 HEC ? GO:0009055 ... Q00471 14647374
    42115 1q90:B (3.1) BS03 HEC ? GO:0009055 ... Q00471 14647374
    42116 1q90:B (3.1) BS04 BCR ? GO:0009055 ... Q00471 14647374
    42117 1q90:B (3.1) BS05 CLA ? GO:0009055 ... Q00471 14647374
    42118 1q90:B (3.1) BS06 TDS ? GO:0009055 ... Q00471 14647374
    42119 1q90:C (3.1) BS01 FES 7.1.1.6 GO:0016020 ... P49728 14647374
    42120 1q90:D (3.1) BS01 HEC ? GO:0005739 ... P23230 14647374
    42121 1q90:D (3.1) BS02 CLA ? GO:0005739 ... P23230 14647374
    42122 1q90:D (3.1) BS03 TDS ? GO:0005739 ... P23230 14647374
    42123 1q90:G (3.1) BS01 BCR ? GO:0009507 ... Q08362 14647374
    42124 1q90:M (3.1) BS01 BCR ? GO:0009512 ... Q42496 14647374
    42125 1q90:N (3.1) BS01 BCR ? GO:0009512 ... P0C1D4 14647374
    42126 1q91:A (1.6) BS01 PO4 3.1.3.- GO:0008253 ... Q9NPB1 15044615
    42127 1q91:A (1.6) BS02 MG 3.1.3.- GO:0008253 ... Q9NPB1 15044615
    42128 1q91:A (1.6) BS03 DPB 3.1.3.- GO:0008253 ... Q9NPB1 15044615 MOAD: Ki=70uM
    PDBbind: -logKd/Ki=4.15, Ki=70uM
    42129 1q92:A (1.4) BS01 MG 3.1.3.- GO:0008253 ... Q9NPB1 15044615
    42130 1q92:A (1.4) BS02 DRM 3.1.3.- GO:0008253 ... Q9NPB1 15044615
    42131 1q94:A (2.4) BS01 peptide ? N/A P04439 15128805
    42132 1q94:D (2.4) BS01 peptide ? N/A P04439 15128805
    42133 1q95:A (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    PDBbind: -logKd/Ki=7.57, Ki=27nM
    42134 1q95:B (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    PDBbind: -logKd/Ki=7.57, Ki=27nM
    42135 1q95:B (2.46) BS02 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    PDBbind: -logKd/Ki=7.57, Ki=27nM
    42136 1q95:C (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42137 1q95:C (2.46) BS02 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42138 1q95:D (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42139 1q95:E (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42140 1q95:E (2.46) BS02 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42141 1q95:F (2.46) BS01 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42142 1q95:F (2.46) BS02 PAL 2.1.3.2 GO:0004070 ... P0A786 15157075 MOAD: Ki=27nM
    42143 1q95:G (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42144 1q95:H (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42145 1q95:I (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42146 1q95:J (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42147 1q95:K (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42148 1q95:L (2.46) BS01 ZN ? GO:0005515 ... P0A7F3 15157075
    42149 1q97:A (2.3) BS01 ATP 2.7.11.1 GO:0004672 ... Q03656 12911299
    42150 1q97:B (2.3) BS01 ADN 2.7.11.1 GO:0004672 ... Q03656 12911299
    42151 1q99:A (2.11) BS01 ANP 2.7.11.1 GO:0004672 ... Q03656 12911299
    42152 1q99:B (2.11) BS01 ANP 2.7.11.1 GO:0004672 ... Q03656 12911299
    42153 1q9d:A (2.35) BS01 F6P 3.1.3.11 GO:0005737 ... P00636 14530289
    42154 1q9d:A (2.35) BS02 MG 3.1.3.11 GO:0005737 ... P00636 14530289
    42155 1q9d:A (2.35) BS03 MG 3.1.3.11 GO:0005737 ... P00636 14530289
    42156 1q9d:A (2.35) BS04 PO4 3.1.3.11 GO:0005737 ... P00636 14530289
    42157 1q9d:A (2.35) BS05 PO4 3.1.3.11 GO:0005737 ... P00636 14530289
    42158 1q9d:A (2.35) BS06 OI1 3.1.3.11 GO:0005737 ... P00636 14530289 MOAD: ic50=1.87uM
    PDBbind: -logKd/Ki=4.60, Kd=25uM
    42159 1q9d:A (2.35) BS07 OI1 3.1.3.11 GO:0005737 ... P00636 14530289 MOAD: ic50=1.87uM
    PDBbind: -logKd/Ki=4.60, Kd=25uM
    42160 1q9d:B (2.35) BS01 OI1 3.1.3.11 GO:0005737 ... P00636 14530289 MOAD: ic50=1.87uM
    PDBbind: -logKd/Ki=4.60, Kd=25uM
    42161 1q9d:B (2.35) BS02 F6P 3.1.3.11 GO:0005737 ... P00636 14530289
    42162 1q9d:B (2.35) BS03 MG 3.1.3.11 GO:0005737 ... P00636 14530289
    42163 1q9d:B (2.35) BS04 MG 3.1.3.11 GO:0005737 ... P00636 14530289
    42164 1q9d:B (2.35) BS05 PO4 3.1.3.11 GO:0005737 ... P00636 14530289
    42165 1q9d:B (2.35) BS06 PO4 3.1.3.11 GO:0005737 ... P00636 14530289
    42166 1q9d:B (2.35) BS07 OI1 3.1.3.11 GO:0005737 ... P00636 14530289 MOAD: ic50=1.87uM
    PDBbind: -logKd/Ki=4.60, Kd=25uM
    42167 1q9i:A (1.6) BS01 HEC 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42168 1q9i:A (1.6) BS02 HEC 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42169 1q9i:A (1.6) BS03 HEC 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42170 1q9i:A (1.6) BS04 HEC 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42171 1q9i:A (1.6) BS05 FAD 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42172 1q9i:A (1.6) BS06 TEO 1.3.2.4 GO:0008202 ... Q07WU7 15109257
    42173 1q9m:A (2.3) BS01 ZN 3.1.4.53 GO:0004114 ... Q08499 12842049
    42174 1q9m:A (2.3) BS02 ROL 3.1.4.53 GO:0004114 ... Q08499 12842049 MOAD: ic50=0.33uM
    PDBbind: -logKd/Ki=6.48, IC50=0.33uM
    42175 1q9m:B (2.3) BS01 ZN 3.1.4.53 GO:0004114 ... Q08499 12842049
    42176 1q9m:B (2.3) BS02 ROL 3.1.4.53 GO:0004114 ... Q08499 12842049 MOAD: ic50=0.33uM
    42177 1q9m:C (2.3) BS01 ZN 3.1.4.53 GO:0004114 ... Q08499 12842049
    42178 1q9m:C (2.3) BS02 ROL 3.1.4.53 GO:0004114 ... Q08499 12842049 MOAD: ic50=0.33uM
    42179 1q9m:D (2.3) BS01 ZN 3.1.4.53 GO:0004114 ... Q08499 12842049
    42180 1q9m:D (2.3) BS02 ROL 3.1.4.53 GO:0004114 ... Q08499 12842049 MOAD: ic50=0.33uM
    42181 1q9o:A (1.79) BS01 MG ? GO:0005576 ... P01837 14625588
    42182 1q9o:A (1.79) BS02 MG ? GO:0005576 ... P01837 14625588
    42183 1q9o:B (1.79) BS01 MG ? N/A I6L985 14625588
    42184 1q9o:C (1.79) BS01 MG ? GO:0005576 ... P01837 14625588
    42185 1q9o:C (1.79) BS02 MG ? GO:0005576 ... P01837 14625588
    42186 1q9o:D (1.79) BS01 MG ? N/A I6L985 14625588
    42187 1q9s:A (2.42) BS01 MG 2.7.1.26 GO:0005515 ... Q969G6 14580199
    42188 1q9s:A (2.42) BS02 ADP 2.7.1.26 GO:0005515 ... Q969G6 14580199
    42189 1q9s:A (2.42) BS03 FMN 2.7.1.26 GO:0005515 ... Q969G6 14580199
    42190 1q9u:B (1.8) BS01 ZN ? GO:0046872 ... Q5KY88 N/A
    42191 1q9u:B (1.8) BS02 ZN ? GO:0046872 ... Q5KY88 N/A
    42192 1q9u:B (1.8) BS03 ZN ? GO:0046872 ... Q5KY88 N/A
    42193 1q9w:A (1.75) BS01 MG ? GO:0046872 ... Q52L64 14625588
    42194 1q9w:A (1.75) BS02 MG ? GO:0046872 ... Q52L64 14625588
    42195 1q9w:C (1.75) BS01 MG ? GO:0046872 ... Q52L64 14625588
    42196 1q9x:A (2.69) BS01 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 15057282 PDBbind: Kd=0.64uM
    42197 1q9x:A (2.69) BS02 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 15057282 PDBbind: Kd=0.64uM
    42198 1q9x:A (2.69) BS03 dna 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 15057282 PDBbind: Kd=0.64uM
    42199 1q9x:A (2.69) BS04 3DR 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 15057282
    42200 1q9x:A (2.69) BS05 DOC 2.7.7.7
    3.1.11.-
    GO:0000166 ... Q38087 15057282

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218