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BioLiP
Download all results in tab-seperated text for 832530 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
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    # PDB
    (Resolution Å)
    Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    28401 1l9h:A (2.6) BS01 ZN ? GO:0000139 ... P02699 11972040
    28402 1l9h:A (2.6) BS02 ZN ? GO:0000139 ... P02699 11972040
    28403 1l9h:A (2.6) BS03 ZN ? GO:0000139 ... P02699 11972040
    28404 1l9h:A (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    28405 1l9h:B (2.6) BS01 ZN ? GO:0000139 ... P02699 11972040
    28406 1l9h:B (2.6) BS02 ZN ? GO:0000139 ... P02699 11972040
    28407 1l9h:B (2.6) BS03 ZN ? GO:0000139 ... P02699 11972040
    28408 1l9h:B (2.6) BS04 RET ? GO:0000139 ... P02699 11972040
    28409 1l9j:C (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    28410 1l9j:D (3.25) BS01 HEM ? GO:0009055 ... P0C0X8 12051924
    28411 1l9j:L (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    28412 1l9j:L (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    28413 1l9j:L (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    28414 1l9j:L (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    28415 1l9j:L (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    28416 1l9j:L (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    28417 1l9j:M (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    28418 1l9j:M (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    28419 1l9j:M (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    28420 1l9j:M (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    28421 1l9j:M (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    28422 1l9j:M (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    28423 1l9j:M (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    28424 1l9j:R (3.25) BS01 BCL ? GO:0009772 ... P0C0Y8 12051924
    28425 1l9j:R (3.25) BS02 BCL ? GO:0009772 ... P0C0Y8 12051924
    28426 1l9j:R (3.25) BS03 BPH ? GO:0009772 ... P0C0Y8 12051924
    28427 1l9j:R (3.25) BS04 FE2 ? GO:0009772 ... P0C0Y8 12051924
    28428 1l9j:R (3.25) BS05 BCL ? GO:0009772 ... P0C0Y8 12051924
    28429 1l9j:R (3.25) BS06 BPH ? GO:0009772 ... P0C0Y8 12051924
    28430 1l9j:S (3.25) BS01 BCL ? GO:0009772 ... P0C0Y9 12051924
    28431 1l9j:S (3.25) BS02 BPH ? GO:0009772 ... P0C0Y9 12051924
    28432 1l9j:S (3.25) BS03 FE2 ? GO:0009772 ... P0C0Y9 12051924
    28433 1l9j:S (3.25) BS04 BCL ? GO:0009772 ... P0C0Y9 12051924
    28434 1l9j:S (3.25) BS05 BCL ? GO:0009772 ... P0C0Y9 12051924
    28435 1l9j:S (3.25) BS06 BPH ? GO:0009772 ... P0C0Y9 12051924
    28436 1l9j:S (3.25) BS07 U10 ? GO:0009772 ... P0C0Y9 12051924
    28437 1l9k:A (2.4) BS01 SAH 2.1.1.56
    2.1.1.57
    2.7.7.48
    3.4.21.91
    3.6.1.15
    3.6.4.13
    GO:0003968 ... P12823 12032088
    28438 1l9l:A (0.92) BS01 SO4 ? GO:0042742 ... P22749 12488100
    28439 1l9l:A (0.92) BS02 SO4 ? GO:0042742 ... P22749 12488100
    28440 1l9l:A (0.92) BS03 SO4 ? GO:0042742 ... P22749 12488100
    28441 1l9m:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28442 1l9m:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28443 1l9n:A (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28444 1l9n:A (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28445 1l9n:A (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28446 1l9n:B (2.1) BS01 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28447 1l9n:B (2.1) BS02 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28448 1l9n:B (2.1) BS03 CA 2.3.2.13 GO:0003810 ... Q08188 11980702
    28449 1l9o:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28450 1l9o:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28451 1l9o:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28452 1l9o:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28453 1l9o:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28454 1l9o:C (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28455 1l9o:C (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28456 1l9p:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28457 1l9p:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28458 1l9p:B (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28459 1l9p:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28460 1l9p:C (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28461 1l9p:C (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28462 1l9q:A (1.7) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28463 1l9q:A (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28464 1l9q:A (1.7) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28465 1l9q:A (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28466 1l9q:B (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28467 1l9q:B (1.7) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28468 1l9q:B (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28469 1l9q:B (1.7) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28470 1l9q:C (1.7) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28471 1l9q:C (1.7) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28472 1l9q:C (1.7) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28473 1l9q:C (1.7) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28474 1l9r:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28475 1l9r:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28476 1l9r:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28477 1l9r:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28478 1l9r:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28479 1l9r:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28480 1l9r:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28481 1l9r:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28482 1l9r:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28483 1l9s:A (1.78) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28484 1l9s:A (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28485 1l9s:A (1.78) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28486 1l9s:B (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28487 1l9s:B (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28488 1l9s:B (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28489 1l9s:C (1.78) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28490 1l9s:C (1.78) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28491 1l9s:C (1.78) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28492 1l9t:A (1.75) BS01 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28493 1l9t:A (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28494 1l9t:A (1.75) BS03 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28495 1l9t:A (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28496 1l9t:B (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28497 1l9t:B (1.75) BS02 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28498 1l9t:B (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28499 1l9t:B (1.75) BS04 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28500 1l9t:C (1.75) BS01 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28501 1l9t:C (1.75) BS02 NO2 1.7.2.1 GO:0005507 ... P38501 12538888
    28502 1l9t:C (1.75) BS03 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28503 1l9t:C (1.75) BS04 CU 1.7.2.1 GO:0005507 ... P38501 12538888
    28504 1l9w:A (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    28505 1l9w:B (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    28506 1l9w:C (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    28507 1l9w:D (2.1) BS01 DHS 4.2.1.10 GO:0003855 ... P24670 11976491
    28508 1l9y:A (2.01) BS01 ZN 3.5.2.6 N/A Q9K578 12507470
    28509 1l9y:A (2.01) BS02 ZN 3.5.2.6 N/A Q9K578 12507470
    28510 1l9y:B (2.01) BS01 ZN 3.5.2.6 N/A Q9K578 12507470
    28511 1l9y:B (2.01) BS02 ZN 3.5.2.6 N/A Q9K578 12507470
    28512 1la0:A (-1.00) BS01 CA ? GO:0003009 ... P09860 12147696
    28513 1la0:A (-1.00) BS02 CA ? GO:0003009 ... P09860 12147696
    28514 1la0:A (-1.00) BS03 CA ? GO:0003009 ... P09860 12147696
    28515 1la2:A (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    28516 1la2:B (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    28517 1la2:C (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    28518 1la2:D (2.65) BS01 NAD 5.5.1.4 GO:0004512 ... P11986 12836703
    28519 1la3:A (-1.00) BS01 CA ? GO:0001750 ... P21457 11980481
    28520 1la6:A (2.0) BS01 HEM ? GO:0004601 ... P45718 12093902
    28521 1la6:B (2.0) BS01 HEM ? GO:0004601 ... P45720 12093902
    28522 1laf:E (2.06) BS01 ARG ? GO:0006865 ... P02911 7929349 MOAD: Kd=14nM
    PDBbind: -logKd/Ki=7.85, Kd=14nM
    28523 1lag:E (2.06) BS01 HIS ? GO:0006865 ... P02911 7929349 MOAD: Kd=500nM
    PDBbind: -logKd/Ki=6.30, Kd=500nM
    28524 1lah:E (2.06) BS01 ORN ? GO:0006865 ... P02911 7929349 MOAD: Kd=30nM
    PDBbind: -logKd/Ki=7.52, Kd=30nM
    28525 1lam:A (1.6) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    28526 1lam:A (1.6) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    28527 1lam:A (1.6) BS03 CO3 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    28528 1lan:A (1.9) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    28529 1lan:A (1.9) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088
    28530 1lan:A (1.9) BS03 LEU 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 7578088 MOAD: Ki=60nM
    PDBbind: -logKd/Ki=7.22, Ki=60nM
    28531 1lap:A (2.7) BS01 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    28532 1lap:A (2.7) BS02 ZN 3.4.11.1
    3.4.11.5
    3.4.13.23
    GO:0004177 ... P00727 2395881
    28533 1lat:A (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    28534 1lat:A (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    28535 1lat:A (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    28536 1lat:A (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    28537 1lat:B (1.9) BS01 dna ? GO:0003700 ... P06536 7664096
    28538 1lat:B (1.9) BS02 dna ? GO:0003700 ... P06536 7664096
    28539 1lat:B (1.9) BS03 ZN ? GO:0003700 ... P06536 7664096
    28540 1lat:B (1.9) BS04 ZN ? GO:0003700 ... P06536 7664096
    28541 1lau:E (1.8) BS01 dna 3.2.2.27 GO:0004844 ... P10186 7845459
    28542 1lax:A (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    28543 1lax:A (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028
    28544 1lax:C (1.85) BS01 GLC ? GO:0005515 ... P0AEX9 12592028
    28545 1lax:C (1.85) BS02 GLC ? GO:0005515 ... P0AEX9 12592028
    28546 1lb2:A (3.1) BS01 dna ? GO:0003677 ... P0ACJ8 12202833
    28547 1lb2:A (3.1) BS02 dna ? GO:0003677 ... P0ACJ8 12202833
    28548 1lb2:A (3.1) BS03 CMP ? GO:0003677 ... P0ACJ8 12202833
    28549 1lb2:B (3.1) BS01 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    28550 1lb2:B (3.1) BS02 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    28551 1lb2:E (3.1) BS01 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    28552 1lb2:E (3.1) BS02 dna 2.7.7.6 GO:0003677 ... P0A7Z4 12202833
    28553 1lb3:A (1.21) BS01 CD ? GO:0005506 ... P29391 12459904
    28554 1lb3:A (1.21) BS02 CD ? GO:0005506 ... P29391 12459904
    28555 1lb3:A (1.21) BS03 CD ? GO:0005506 ... P29391 12459904
    28556 1lb3:A (1.21) BS04 GOL ? GO:0005506 ... P29391 12459904
    28557 1lb3:A (1.21) BS05 GOL ? GO:0005506 ... P29391 12459904
    28558 1lb5:A (2.4) BS01 peptide 2.3.2.27 GO:0004842 ... Q9Y4K3 12140561
    28559 1lb6:A (1.8) BS01 peptide 2.3.2.27 GO:0004842 ... Q9Y4K3 12140561
    28560 1lb8:A (2.3) BS01 AMQ ? GO:0015276 ... P19491 12015593 BindingDB: Ki=17nM
    28561 1lb8:B (2.3) BS01 AMQ ? GO:0015276 ... P19491 12015593 BindingDB: Ki=17nM
    28562 1lb9:A (2.3) BS01 DNQ ? GO:0015276 ... P19491 12015593
    28563 1lb9:B (2.3) BS01 DNQ ? GO:0015276 ... P19491 12015593
    28564 1lba:A (2.2) BS01 ZN 3.5.1.28 GO:0008270 ... P00806 8171031
    28565 1lbc:A (1.8) BS01 ZN ? GO:0015276 ... P19491 12015593
    28566 1lbc:A (1.8) BS02 GLU ? GO:0015276 ... P19491 12015593
    28567 1lbc:A (1.8) BS03 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    28568 1lbc:A (1.8) BS04 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    28569 1lbc:B (1.8) BS01 ZN ? GO:0015276 ... P19491 12015593
    28570 1lbc:B (1.8) BS02 ZN ? GO:0015276 ... P19491 12015593
    28571 1lbc:B (1.8) BS03 GLU ? GO:0015276 ... P19491 12015593
    28572 1lbc:B (1.8) BS04 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    28573 1lbc:C (1.8) BS01 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    28574 1lbc:C (1.8) BS02 GLU ? GO:0015276 ... P19491 12015593
    28575 1lbc:C (1.8) BS03 CYZ ? GO:0015276 ... P19491 12015593 BindingDB: EC50=7600nM
    28576 1lbf:A (2.05) BS01 137 4.1.1.48 GO:0000162 ... Q06121 12054868 MOAD: Kd=0.014uM
    PDBbind: -logKd/Ki=7.85, Kd=0.014uM
    28577 1lbg:A (4.8) BS01 dna ? GO:0000976 ... P03023 8638105
    28578 1lbg:D (4.8) BS01 dna ? GO:0000976 ... P03023 8638105
    28579 1lbh:A (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    28580 1lbh:B (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    28581 1lbh:C (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    28582 1lbh:D (3.2) BS01 IPT ? GO:0000976 ... P03023 8638105
    28583 1lbk:A (1.86) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 12473455 MOAD: Kd=668uM
    28584 1lbk:B (1.86) BS01 GSH 2.5.1.18 GO:0000302 ... P09211 12473455 MOAD: Kd=668uM
    28585 1lbl:A (2.4) BS01 137 4.1.1.48 GO:0000162 ... Q06121 12054868 MOAD: Kd=0.014uM
    28586 1lbm:A (2.8) BS01 137 5.3.1.24 GO:0000162 ... Q56320 12356303
    28587 1lbs:A (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28588 1lbs:B (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28589 1lbs:C (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28590 1lbs:D (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28591 1lbs:E (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28592 1lbs:F (2.6) BS01 HEE 3.1.1.3 GO:0004806 ... P41365 8527460
    28593 1lbt:A (2.5) BS01 T80 3.1.1.3 GO:0004806 ... P41365 8527460
    28594 1lbt:B (2.5) BS01 T80 3.1.1.3 GO:0004806 ... P41365 8527460
    28595 1lbu:A (1.8) BS01 ZN 3.4.17.14 GO:0004180 ... P00733 N/A
    28596 1lbx:A (2.4) BS01 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    28597 1lbx:A (2.4) BS02 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    28598 1lbx:A (2.4) BS03 IPD 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    28599 1lbx:B (2.4) BS01 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584
    28600 1lbx:B (2.4) BS02 CA 3.1.3.11
    3.1.3.25
    GO:0006020 ... O30298 11940584

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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