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BioLiP
Download all results in tab-seperated text for 2 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (resolution)     		Site
    #     		Peptide
    sequence         		EC
    number     		GO
    terms     		UniProt PubMed Binding
    affinity
    1 4y74:H
    (2.7)    		 BS02 >4y74:d (identical to 4y74:c, 4y74:e, 4y74:f, 4y74:g, 4y74:h)
    LAL
    		 3.4.25.1 GO:0004298 ... P25043 26020686
    2 4y74:K
    (2.7)    		 BS01 >4y74:d (identical to 4y74:c, 4y74:e, 4y74:f, 4y74:g, 4y74:h)
    LAL
    		 3.4.25.1 GO:0004298 ... P30656 26020686
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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