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BioLiP
Download all results in tab-seperated text for 9 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    DNA
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 6lab:K
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P68431 33590100
    2 6lab:L
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000781 ... P62805 33590100
    3 6lab:M
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P04908 33590100
    4 6lab:N
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P06899 33590100
    5 6lab:O
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P68431 33590100
    6 6lab:P
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000781 ... P62805 33590100
    7 6lab:Q
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P04908 33590100
    8 6lab:R
    (3.2)
    BS01 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000786 ... P06899 33590100
    9 6lab:U
    (3.2)
    BS03 >6lab:S (identical to 6lab:I, 7xvm:I, 7xvm:S, 7xx5:I, 7xx5:S, 7xx6:I, 7xx6:S, 7xx6:c, 7xx6:m, 7xx7:I, 7xx7:S, 8yti:I, 8yti:S)
    gcttttttttttcacaatcccggtgccgaggccgctcaattggtcgtaga
    cagctctagcaccgcttaaacgcacgtacggaatccgtacgtgcgtttaa
    gcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggatt
    gtgaaaaaaaaaagctgca
    ? GO:0000785 ... P07305 33590100

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218