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BioLiP
Download all results in tab-seperated text for 9 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    RNA
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 8rxh:LA
    (2.93)
    BS03 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0002181 ... Q4FWX5 38722744
    2 8rxh:LQ
    (2.93)
    BS03 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003723 ... Q4QJ37 38722744
    3 8rxh:LU
    (2.93)
    BS02 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0002181 ... Q4Q0X2 38722744
    4 8rxh:LY
    (2.93)
    BS02 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003735 ... Q4Q504 38722744
    5 8rxh:Ld
    (2.93)
    BS02 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003723 ... E9AEK1 38722744
    6 8rxh:Lh
    (2.93)
    BS03 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003735 ... Q4QDP9 38722744
    7 8rxh:Lk
    (2.93)
    BS03 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003735 ... Q4Q8X0 38722744
    8 8rxh:Lo
    (2.93)
    BS03 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003735 ... Q4QC01 38722744
    9 8rxh:ST
    (2.93)
    BS01 >8rxh:L3 (identical to 8rxx:L3)
    agugguaaugcgaaacacuugccagguaacaaaucaauccucccacggug
    agcuuucuuuucaccauaauccaccuugggccuuuuuacuuucgcguugu
    ucggagcgggggcucaagauugaaaaaugcagcucuuacugucauuugug
    aguucugcgcauuaaagcaaaaaccuggggugu
    .<<<....>>>.....<<<..<<<<<<.......<<...<<<<...<<<<
    <<.......>>>>>><...<<.<.<<<<<<<<<<<.......<<......
    .>>....>>>>>>>>>>>.>.>>....><..<.<......>.>..>.>.>
    >>...>>...............>>>>>>>>>..
    ? GO:0003735 ... Q4Q3M1 38722744

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218