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BioLiP
Download all results in tab-seperated text for 12 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    RNA
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 5gmk:A
    (3.4)
    BS02 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000244 ... P33334 27445308
    2 5gmk:F
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000349 ... P28320 27445308
    3 5gmk:H
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000350 ... P21374 27445308
    4 5gmk:I
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000384 ... P53277 27445308
    5 5gmk:P
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000350 ... P28004 27445308
    6 5gmk:Q
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000398 ... P38241 27445308
    7 5gmk:R
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000387 ... Q12046 27445308
    8 5gmk:S
    (3.4)
    BS02 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000398 ... Q03772 27445308
    9 5gmk:T
    (3.4)
    BS02 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000282 ... P25337 27445308
    10 5gmk:c
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000350 ... Q03654 27445308
    11 5gmk:d
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000398 ... Q12309 27445308
    12 5gmk:n
    (3.4)
    BS01 >5gmk:E (identical to 7dco:F, 5gm6:E, 6j6g:E, 6j6h:E, 6j6n:E, 6j6q:E, 5wsg:E, 5ylz:D)
    guucgcgaaguaacccuucguggacauuuggucaauuugaaacaauacag
    agaugaucagcaguuccccugcauaaggaugaaccguuuuacaaagagau
    uua
    <<<<<<<<<<.....>>>>>>>>>>.........................
    ............<<<..<<<.....>>>...>>>................
    ...
    ? GO:0000348 ... P40968 27445308

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218