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BioLiP
Download all results in tab-seperated text for 10 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • The sequence is converted from residues with experimentally determined coordinates in the structure; residues not observed in the 3D structure are excluded.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.
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    # PDB
    (resolution)
    Site
    #
    RNA
    sequence
    EC
    number
    GO
    terms
    UniProt PubMed Binding
    affinity
    1 6sgc:C2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    N/A GO:0003735 ... N/A 31768042
    2 6sgc:G2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    N/A GO:0042254 ... N/A 31768042
    3 6sgc:L2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    N/A GO:0003735 ... N/A 31768042
    4 6sgc:N2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0002181 ... G1T0C1 31768042
    5 6sgc:P2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0002181 ... G1SCJ6 31768042
    6 6sgc:X2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0000027 ... G1SE76 31768042
    7 6sgc:Y2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0002181 ... G1SQH0 31768042
    8 6sgc:h2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0000463 ... G1SIT5 31768042
    9 6sgc:j2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0003723 ... U3KPD5 31768042
    10 6sgc:l2
    (2.8)
    BS02 >6sgc:84 (identical to 8b5l:8, 8b6c:8, 9bdl:A58S, 9bdn:A58S, 9bdp:A58S, 8bhf:C2, 8bpo:C1, 6d90:8, 6d9j:8, 6hcf:82, 6hcj:81, 6hcm:82, 6hcq:81, 5lzs:8, 5lzt:8, 5lzu:8, 5lzv:8, 5lzw:8, 5lzx:8, 5lzy:8, 5lzz:8, 7mdz:8, 6mtb:8, 6mtc:8, 6mtd:8, 6mte:8, 7nwg:81, 7nwh:8, 6p5i:8, 6p5j:8, 6p5k:8, 6p5n:8, 6r5q:8, 6r6g:8, 6r7q:8, 6t59:84, 7tor:A58S, 7uck:8)
    cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
    uagcugcgagaauuaaugugaauugcagguugaucaucgacacuucgaac
    gcacuugcggccccggguuccucccggggcuacgccugucugagcgucgc
    u
    .........................................<<<<<<<<<
    ....>>>>.....<.<<<......>>........>>>..>...>>>....
    <<<..>>><<<<<<<<<....>.>>>>>>>>...................
    .
    ? GO:0003735 ... G1TTN1 31768042

    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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