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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

BioLiP
Download all results in tab-seperated text for 48291 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
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  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    10801 2xfh:A (1.9) BS03 CL6 1.14.13.154 GO:0004497 ... P48635 20845962 MOAD: Kd<0.01uM
    10802 2xfi:A (1.73) BS01 XFI 3.4.23.46 GO:0004190 ... P56817 20579874 MOAD: ic50=15nM
    PDBbind: -logKd/Ki=7.82, IC50=15nM
    10803 2xfj:A (1.8) BS01 VG5 3.4.23.46 GO:0004190 ... P56817 20579874 MOAD: ic50=13nM
    PDBbind: -logKd/Ki=7.89, IC50=13nM
    BindingDB: IC50=310nM
    10804 2xfk:A (1.8) BS01 AA9 3.4.23.46 GO:0004190 ... P56817 20579874 MOAD: ic50=3nM
    PDBbind: -logKd/Ki=8.52, IC50=3nM
    10805 2xfm:A (-1.00) BS01 rna 3.1.26.- GO:0003723 ... Q9JMB7 21237665 PDBbind: Kd=0.9uM
    10806 2xfn:A (1.6) BS02 XCG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 MOAD: Ki=8.3uM
    10807 2xfn:B (1.6) BS02 XCG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 MOAD: Ki=8.3uM
    10808 2xfo:A (2.1) BS03 XCG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 MOAD: Ki=58uM
    10809 2xfo:B (2.1) BS03 XCG 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 MOAD: Ki=58uM
    10810 2xfp:A (1.66) BS02 ISN 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 BindingDB: IC50=18750nM, Ki=3000nM
    10811 2xfp:B (1.66) BS02 ISN 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P27338 20855894 BindingDB: IC50=18750nM, Ki=3000nM
    10812 2xg3:A (1.2) BS01 GAL ? GO:0030246 ... P17931 20873837 PDBbind: -logKd/Ki=4.74, Kd=18.2uM
    10813 2xg5:A (2.0) BS01 EC2 ? GO:0005515 ... P15319 20586493 MOAD: ic50=22uM
    PDBbind: -logKd/Ki=4.66, IC50=22uM
    10814 2xg9:A (1.8) BS01 NOJ 3.2.1.2 GO:0000272 ... P16098 21085740 PDBbind: -logKd/Ki=4.15, Ki=70uM
    10815 2xg9:A (1.8) BS02 GLC 3.2.1.2 GO:0000272 ... P16098 21085740 PDBbind: -logKd/Ki=4.15, Ki=70uM
    10816 2xgm:A (2.55) BS01 LXN ? GO:0016757 ... Q8PC69 20640461 PDBbind: -logKd/Ki=3.00, Kd=1mM
    10817 2xgo:A (2.6) BS01 ZKD ? GO:0016757 ... Q8PC69 20640461 PDBbind: -logKd/Ki=3.00, Kd=1mM
    10818 2xgs:A (2.39) BS01 44P ? GO:0016757 ... Q8PC69 20640461 MOAD: Kd=0.53mM
    PDBbind: -logKd/Ki=3.28, Kd=0.530mM
    10819 2xgs:B (2.39) BS01 44P ? GO:0016757 ... Q8PC69 20640461 MOAD: Kd=0.53mM
    10820 2xh5:A (2.72) BS02 X37 2.7.11.1 GO:0004672 ... P31751 20151677 PDBbind: -logKd/Ki=7.57, IC50=27nM
    10821 2xhd:A (1.8) BS02 7T9 ? GO:0015276 ... P42262 20614889 BindingDB: EC50=2500nM
    10822 2xhd:B (1.8) BS02 7T9 ? GO:0015276 ... P42262 20614889 BindingDB: EC50=2500nM
    10823 2xhi:A (1.55) BS01 dna 3.2.2.-
    4.2.99.18    		 GO:0000978 ... O15527 21220122 PDBbind: Kd=0.17nM
    10824 2xhi:A (1.55) BS02 dna 3.2.2.-
    4.2.99.18    		 GO:0000978 ... O15527 21220122 PDBbind: Kd=0.17nM
    10825 2xhm:A (1.96) BS01 K26 3.4.15.1 GO:0006508 ... Q10714 20599761 PDBbind: -logKd/Ki=6.80, Ki=0.16uM
    10826 2xhr:A (2.2) BS01 C0P 3.6.4.10 GO:0005524 ... P07900 20718493 MOAD: Kd=0.0048uM
    PDBbind: -logKd/Ki=8.32, Kd=4.8nM
    10827 2xht:A (2.27) BS01 C0Y 3.6.4.10 GO:0005524 ... P07900 20718493 MOAD: Kd=1.1uM
    PDBbind: -logKd/Ki=5.96, Kd=1.1uM
    10828 2xhx:A (2.801) BS01 T5M 3.6.4.10 GO:0005524 ... P07900 20718493 PDBbind: -logKd/Ki=6.60, Kd=0.25uM
    10829 2xi7:A (2.2) BS03 XI7 2.7.7.48
    3.1.-.-    		 N/A A5HC98 20862319 PDBbind: -logKd/Ki=5.14, Kd=7.20uM
    10830 2xib:A (2.2) BS01 DFU ? GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=55.1nM
    10831 2xib:B (2.2) BS01 DFU ? GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=55.1nM
    PDBbind: -logKd/Ki=7.26, Kd=55.1nM
    10832 2xib:C (2.2) BS01 DFU ? GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=55.1nM
    10833 2xib:D (2.2) BS01 DFU ? GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=55.1nM
    10834 2xii:A (1.8) BS02 TA9 3.2.1.51 GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=63.3nM
    PDBbind: -logKd/Ki=7.20, Kd=63.3nM
    10835 2xii:B (1.8) BS02 TA9 3.2.1.51 GO:0004560 ... Q8A3I4 20665773 MOAD: Kd=63.3nM
    10836 2xix:A (2.4) BS01 XIX 2.7.11.1 GO:0004672 ... P11309 21358046 PDBbind: -logKd/Ki=2.30, IC50>5000uM
    10837 2xiy:A (2.2) BS01 XIY 2.7.11.1 GO:0004672 ... P11309 21358046 PDBbind: -logKd/Ki=2.44, IC50=3600uM
    10838 2xiz:A (2.21) BS01 XIZ 2.7.11.1 GO:0004672 ... P11309 21358046 PDBbind: -logKd/Ki=3.89, IC50=130uM
    10839 2xj0:A (3.1) BS01 XJ0 2.7.11.1 GO:0004672 ... P11309 21358046 PDBbind: -logKd/Ki=2.82, IC50=1500uM
    10840 2xj1:A (2.13) BS01 XJ1 2.7.11.1 GO:0004672 ... P11309 21358046 MOAD: Kd=28nM
    PDBbind: -logKd/Ki=7.55, Kd=28nM
    BindingDB: IC50=13nM
    10841 2xj2:A (2.2) BS01 985 2.7.11.1 GO:0004672 ... P11309 21358046 MOAD: Kd=66nM
    PDBbind: -logKd/Ki=7.18, Kd=66nM
    BindingDB: IC50=57nM
    10842 2xj7:A (2.0) BS01 GC2 3.2.1.169 GO:0005975 ... Q89ZI2 20851343 MOAD: Kd=246nM
    PDBbind: -logKd/Ki=6.66, Ki=220nM
    10843 2xj7:B (2.0) BS01 GC2 3.2.1.169 GO:0005975 ... Q89ZI2 20851343 MOAD: Kd=246nM
    10844 2xjg:A (2.25) BS01 XJG 3.6.4.10 GO:0005524 ... P07900 20662534 MOAD: Kd=0.015uM
    PDBbind: -logKd/Ki=7.82, Kd=15nM
    10845 2xjj:A (1.9) BS01 L81 3.6.4.10 GO:0005524 ... P07900 20662534 MOAD: Kd=0.31uM
    PDBbind: -logKd/Ki=6.51, Kd=0.31uM
    10846 2xjj:B (1.9) BS01 L81 3.6.4.10 GO:0005524 ... P07900 20662534 MOAD: Kd=0.31uM
    10847 2xjx:A (1.66) BS01 XJX 3.6.4.10 GO:0005524 ... P07900 20662534 MOAD: Kd=0.71nM
    PDBbind: -logKd/Ki=9.15, Kd=0.71nM
    BindingDB: IC50=20nM
    10848 2xk1:A (2.8) BS01 EWB 3.4.16.4 GO:0000270 ... P39045 24900305 PDBbind: -logKd/Ki=5.74, IC50=1.8uM
    10849 2xk2:A (1.95) BS01 ADP 3.6.4.10 GO:0005524 ... P07900 20718493 MOAD: Kd=10uM
    10850 2xk3:A (2.2) BS01 XK3 2.7.11.1 GO:0004672 ... P51955 20936789 PDBbind: -logKd/Ki=5.68, IC50=2.1uM
    10851 2xk4:A (2.1) BS01 OL2 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=16.9uM
    PDBbind: -logKd/Ki=4.77, IC50=16.9uM
    BindingDB: IC50=16900nM
    10852 2xk6:A (2.2) BS01 EQH 2.7.11.1 GO:0004672 ... P51955 20936789 PDBbind: -logKd/Ki=5.80, IC50=1.6uM
    10853 2xk7:A (1.992) BS01 30E 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=1.5uM
    PDBbind: -logKd/Ki=5.82, IC50=1.5uM
    BindingDB: IC50=1500nM
    10854 2xk8:A (2.001) BS01 5R1 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.4uM
    PDBbind: -logKd/Ki=5.62, IC50=2.4uM
    BindingDB: IC50=1300nM
    10855 2xk9:A (2.35) BS01 XK9 2.7.11.1 GO:0004672 ... O96017 21963792 MOAD: ic50=0.03nM
    PDBbind: -logKd/Ki=10.15, IC50=0.07nM
    10856 2xkc:A (2.5) BS01 4VQ 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.6uM
    PDBbind: -logKd/Ki=5.59, IC50=2.6uM
    BindingDB: IC50=2300nM
    10857 2xkd:A (1.96) BS01 T3M 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=2.3uM
    PDBbind: -logKd/Ki=5.64, IC50=2.3uM
    BindingDB: IC50=1600nM
    10858 2xke:A (2.203) BS01 WI2 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=4.2uM
    PDBbind: -logKd/Ki=5.38, IC50=4.2uM
    BindingDB: IC50=4200nM
    10859 2xkf:A (2.35) BS01 BX1 2.7.11.1 GO:0004672 ... P51955 20936789 MOAD: ic50=0.87uM
    PDBbind: -logKd/Ki=6.06, IC50=0.87uM
    BindingDB: IC50=410nM
    10860 2xkw:A (2.02) BS01 P1B ? GO:0003677 ... P37231 N/A BindingDB: EC50=250nM, IC50=1700nM, Kd=871nM, Ki=420nM
    10861 2xkw:B (2.02) BS01 P1B ? GO:0003677 ... P37231 N/A BindingDB: EC50=250nM, IC50=1700nM, Kd=871nM, Ki=420nM
    10862 2xln:A (2.4) BS01 EWA 3.4.16.4 GO:0000270 ... P39045 24900305 PDBbind: -logKd/Ki=4.48, IC50=33uM
    10863 2xm1:A (2.0) BS01 LTM 3.2.1.169 GO:0005975 ... Q89ZI2 20689974 MOAD: Kd=8.5uM
    PDBbind: -logKd/Ki=5.07, Kd=8.5uM
    10864 2xm1:B (2.0) BS01 LTM 3.2.1.169 GO:0005975 ... Q89ZI2 20689974 MOAD: Kd=8.5uM
    10865 2xm2:A (1.95) BS01 LOG 3.2.1.169 GO:0005975 ... Q89ZI2 20689974 MOAD: Ki=24uM
    PDBbind: -logKd/Ki=4.62, Ki=24uM
    10866 2xm2:B (1.95) BS01 LOG 3.2.1.169 GO:0005975 ... Q89ZI2 20689974 MOAD: Ki=24uM
    10867 2xm8:A (3.4) BS01 B4W 2.7.11.1 GO:0004672 ... O96017 21186793 PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    BindingDB: IC50=160nM
    10868 2xm9:A (2.5) BS01 LWH 2.7.11.1 GO:0004672 ... O96017 21186793 MOAD: ic50=0.009uM
    PDBbind: -logKd/Ki=8.05, IC50=0.009uM
    10869 2xmy:A (1.9) BS01 CDK 2.7.11.22 GO:0000082 ... P24941 21035734 MOAD: Ki=0.11nM
    PDBbind: -logKd/Ki=9.96, Ki=0.11nM
    BindingDB: Ki=0.11nM
    10870 2xn3:A (2.09) BS01 ID8 ? GO:0004867 ... P05543 21325280 MOAD: Kd=89nM
    PDBbind: -logKd/Ki=5.92, Kd=1198nM
    10871 2xn3:B (2.09) BS01 ID8 ? N/A P05543 21325280 PDBbind: -logKd/Ki=5.92, Kd=1198nM
    10872 2xn5:A (1.7) BS01 FUN ? GO:0004867 ... P05543 21325280 MOAD: Kd=123nM
    PDBbind: -logKd/Ki=6.69, Kd=205nM
    10873 2xn6:A (1.29) BS04 F6Y ? GO:0004867 ... P05543 21325280 PDBbind: -logKd/Ki=8.80, Kd=1.6nM
    10874 2xn6:A (1.29) BS05 T44 ? GO:0004867 ... P05543 21325280 PDBbind: -logKd/Ki=8.80, Kd=1.6nM
    10875 2xn6:B (1.29) BS01 T44 ? N/A P05543 21325280 PDBbind: -logKd/Ki=8.80, Kd=1.6nM
    10876 2xn7:A (1.43) BS01 T44 ? GO:0004867 ... P05543 21325280 PDBbind: -logKd/Ki=10.00, Kd<0.1nM
    10877 2xn7:A (1.43) BS02 F6Z ? GO:0004867 ... P05543 21325280 PDBbind: -logKd/Ki=10.00, Kd<0.1nM
    10878 2xn7:B (1.43) BS01 T44 ? N/A P05543 21325280 PDBbind: -logKd/Ki=10.00, Kd<0.1nM
    10879 2xnb:A (1.85) BS01 Y8L 2.7.11.22 GO:0000082 ... P24941 21035734 MOAD: Ki=149nM
    PDBbind: -logKd/Ki=6.83, Ki=149nM
    10880 2xne:A (2.8) BS01 ASH 2.7.11.1 GO:0000212 ... O14965 20833547 PDBbind: -logKd/Ki=6.72, IC50=0.190uM
    BindingDB: IC50=190nM
    10881 2xng:A (2.605) BS01 A0H 2.7.11.1 GO:0000212 ... O14965 20833547 PDBbind: -logKd/Ki=7.22, IC50=0.060uM
    10882 2xni:A (3.3) BS03 TR8 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0006508 ... P27958 20801653 PDBbind: -logKd/Ki=7.37, IC50=43nM
    10883 2xnj:A (1.9) BS01 FAD 1.18.1.2
    1.19.1.1    		 GO:0004324 ... P28861 21306142 MOAD: Kd=1.1nM
    10884 2xnj:A (1.9) BS02 NAP 1.18.1.2
    1.19.1.1    		 GO:0004324 ... P28861 21306142 MOAD: Kd=7.5uM
    10885 2xnj:B (1.9) BS01 FAD 1.18.1.2
    1.19.1.1    		 GO:0004324 ... P28861 21306142 MOAD: Kd=1.1nM
    10886 2xnj:B (1.9) BS02 NAP 1.18.1.2
    1.19.1.1    		 GO:0004324 ... P28861 21306142 MOAD: Kd=7.5uM
    10887 2xnm:A (1.85) BS01 WGZ 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=0.16uM
    PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    BindingDB: IC50=25nM
    10888 2xnn:A (2.5) BS01 430 2.7.11.1 GO:0004672 ... P51955 21366329 PDBbind: -logKd/Ki=4.30, IC50>50uM
    BindingDB: IC50=>50000nM
    10889 2xno:A (1.98) BS01 ED8 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=1.18uM
    PDBbind: -logKd/Ki=5.93, IC50=1.18uM
    BindingDB: IC50=1180nM
    10890 2xnp:A (1.98) BS01 WCX 2.7.11.1 GO:0004672 ... P51955 21366329 MOAD: ic50=0.36uM
    PDBbind: -logKd/Ki=6.44, IC50=0.36uM
    BindingDB: IC50=570nM
    10891 2xnr:A (1.6) BS01 rna ? GO:0003676 ... P38996 20805243 PDBbind: Kd=110uM
    10892 2xnv:A (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10893 2xnv:A (2.44) BS02 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10894 2xnv:B (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10895 2xnv:C (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10896 2xnv:D (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10897 2xnv:E (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10898 2xnv:E (2.44) BS02 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10899 2xnv:F (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10900 2xnv:F (2.44) BS02 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10901 2xnv:G (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10902 2xnv:H (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10903 2xnv:I (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10904 2xnv:J (2.44) BS01 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10905 2xnv:J (2.44) BS02 VU3 ? GO:0004888 ... Q8WSF8 21920761 MOAD: Ki=5uM
    10906 2xo8:A (2.4) BS01 H70 ? GO:0003774 ... P08799 21534527 PDBbind: -logKd/Ki=4.33, IC50=47.2uM
    10907 2xog:A (1.72) BS01 SFB 4.6.1.18 GO:0003676 ... P61823 21205197 MOAD: Ki=0.37mM
    PDBbind: -logKd/Ki=3.43, Ki=0.37mM
    10908 2xog:B (1.72) BS01 SFB 4.6.1.18 GO:0003676 ... P61823 21205197 MOAD: Ki=0.37mM
    10909 2xoi:A (1.72) BS01 SFB 4.6.1.18 GO:0003676 ... P61823 21205197 MOAD: Ki=0.00046M
    PDBbind: -logKd/Ki=3.34, Ki=0.46mM
    10910 2xoi:B (1.72) BS01 SFB 4.6.1.18 GO:0003676 ... P61823 21205197 MOAD: Ki=0.00046M
    10911 2xow:A (2.09) BS01 ISM 3.4.21.105 GO:0004252 ... P09391 20890268 PDBbind: -logKd/Ki=5.22, IC50=6uM
    10912 2xp2:A (1.9) BS01 VGH 2.7.10.1 GO:0004672 ... Q9UM73 21812414 PDBbind: -logKd/Ki=9.00, IC50<1.0nM
    BindingDB: IC50=20nM, Ki=8.2nM, EC50=22840nM, Kd=3.3nM
    10913 2xp3:A (2.0) BS01 B21 5.2.1.8 GO:0000413 ... Q13526 20932746 PDBbind: -logKd/Ki=3.00, IC50>1000uM
    BindingDB: IC50=>1000000nM
    10914 2xp4:A (1.8) BS01 G14 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=180uM
    PDBbind: -logKd/Ki=3.74, IC50=180uM
    10915 2xp5:A (1.9) BS01 4FF 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=360uM
    PDBbind: -logKd/Ki=3.44, IC50=360uM
    10916 2xp6:A (1.9) BS01 4G2 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=20uM
    PDBbind: -logKd/Ki=4.70, IC50=20uM
    10917 2xp7:A (2.0) BS01 4F8 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: Kd=1.7uM
    PDBbind: -logKd/Ki=5.77, Kd=1.7uM
    BindingDB: Kd=1700nM, IC50=1460nM
    10918 2xp8:A (2.1) BS01 4FY 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=15uM
    PDBbind: -logKd/Ki=4.82, IC50=15uM
    BindingDB: IC50=15000nM
    10919 2xpa:A (1.9) BS01 4G5 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=4.1uM
    PDBbind: -logKd/Ki=5.39, IC50=4.1uM
    BindingDB: IC50=4100nM
    10920 2xpb:A (2.0) BS01 4GE 5.2.1.8 GO:0000413 ... Q13526 20932746 MOAD: ic50=2uM
    PDBbind: -logKd/Ki=5.70, IC50=2.0uM
    BindingDB: IC50=2000nM
    10921 2xpc:A (1.49) BS01 051 6.3.2.9 GO:0005515 ... P14900 21524830 MOAD: Ki=125uM
    PDBbind: -logKd/Ki=3.90, Ki=125uM
    10922 2xpk:A (2.4) BS01 Z0M 3.2.1.169 N/A Q0TR53 21095575 MOAD: Ki=0.005nM
    PDBbind: -logKd/Ki=11.30, Ki=0.005nM
    10923 2xpk:B (2.4) BS01 Z0M 3.2.1.169 N/A Q0TR53 21095575 MOAD: Ki=0.005nM
    PDBbind: -logKd/Ki=11.30, Ki=0.005nM
    10924 2xru:A (2.9) BS01 400 2.7.11.1 GO:0000212 ... O14965 20817473 PDBbind: -logKd/Ki=7.51, IC50=31nM
    10925 2xrz:A (2.2) BS01 dna 4.1.99.3 GO:0000166 ... Q8PYK9 21892138 PDBbind: Kd=44nM
    10926 2xrz:A (2.2) BS02 dna 4.1.99.3 GO:0000166 ... Q8PYK9 21892138 PDBbind: Kd=44nM
    10927 2xrz:B (2.2) BS01 dna 4.1.99.3 GO:0000166 ... Q8PYK9 21892138 PDBbind: Kd=44nM
    10928 2xrz:B (2.2) BS02 dna 4.1.99.3 GO:0000166 ... Q8PYK9 21892138 PDBbind: Kd=44nM
    10929 2xs2:A (1.35) BS01 rna ? GO:0003676 ... Q64368 22021443 PDBbind: Kd=38.2nM
    10930 2xsb:A (2.11) BS01 GDL 3.2.1.169 GO:0005975 ... Q2CEE3 20863279 MOAD: ic50=11uM
    PDBbind: -logKd/Ki=4.96, IC50=11uM
    10931 2xtk:A (2.0) BS01 AZM 3.2.1.14 GO:0004553 ... B0Y2Y2 21044846 MOAD: ic50=164uM
    PDBbind: -logKd/Ki=3.79, IC50=164uM
    10932 2xtk:B (2.0) BS01 AZM 3.2.1.14 GO:0004553 ... B0Y2Y2 21044846 MOAD: ic50=164uM
    10933 2xtm:A (1.7) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 MOAD: Kd=630nM
    10934 2xtm:B (1.7) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 MOAD: Kd=630nM
    10935 2xtn:A (1.9) BS01 GTP ? GO:0005525 ... Q9UG22 21059949 MOAD: Kd=40nM
    PDBbind: -logKd/Ki=7.40, Kd=40nM
    10936 2xto:A (2.8) BS01 GDP ? GO:0005525 ... Q9UG22 21059949 PDBbind: -logKd/Ki=6.20, Kd=630nM
    10937 2xu1:A (1.45) BS01 424 3.4.22.15 GO:0006508 ... P07711 21184410 PDBbind: -logKd/Ki=7.66, IC50=0.022uM
    10938 2xu3:A (0.9) BS01 XU3 3.4.22.15 GO:0006508 ... P07711 21184410 PDBbind: -logKd/Ki=6.80, IC50=0.16uM
    10939 2xu4:A (1.12) BS01 DJT 3.4.22.15 GO:0006508 ... P07711 21184410 PDBbind: -logKd/Ki=6.47, IC50=0.34uM
    10940 2xu5:A (1.6) BS01 XU5 3.4.22.15 GO:0006508 ... P07711 21184410 PDBbind: -logKd/Ki=6.89, IC50=0.13uM
    10941 2xuc:A (2.3) BS01 XRG 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=79uM
    PDBbind: -logKd/Ki=4.10, IC50=79uM
    10942 2xuc:A (2.3) BS02 XRG 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=79uM
    PDBbind: -logKd/Ki=4.10, IC50=79uM
    10943 2xuc:B (2.3) BS01 XRG 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=79uM
    10944 2xuc:B (2.3) BS02 XRG 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=79uM
    10945 2xuc:C (2.3) BS01 XRG 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=79uM
    10946 2xud:A (2.65) BS01 DME 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=460nM
    10947 2xuf:A (2.55) BS01 TZ4 3.1.1.7 GO:0001919 ... P21836 21090615 PDBbind: -logKd/Ki=14.39, Kd=4.1fM
    10948 2xui:A (2.6) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 PDBbind: -logKd/Ki=15.00, Kd=1.0fM
    BindingDB: Ki=0.410nM, Kd=0.00041nM
    10949 2xui:B (2.6) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10950 2xuj:A (2.65) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10951 2xuj:B (2.65) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10952 2xuk:A (2.75) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10953 2xuk:B (2.75) BS01 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10954 2xup:A (2.7) BS02 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 PDBbind: -logKd/Ki=12.39, Kd=0.41pM
    BindingDB: Ki=0.410nM, Kd=0.00041nM
    10955 2xup:B (2.7) BS02 TZ5 3.1.1.7 GO:0001919 ... P21836 21090615 BindingDB: Ki=0.410nM, Kd=0.00041nM
    10956 2xuz:A (1.9) BS01 EB4 ? GO:0005737 ... P40409 21802011 PDBbind: -logKd/Ki=7.40, Kd=0.04uM
    10957 2xv1:A (2.15) BS01 ECA ? GO:0005737 ... P40409 21802011 MOAD: Kd=1.03uM
    PDBbind: -logKd/Ki=5.99, Kd=1.03uM
    10958 2xvd:A (1.7) BS01 AS6 2.7.10.1 GO:0004672 ... P54760 21441027 MOAD: ic50=0.002uM
    PDBbind: -logKd/Ki=8.70, IC50=0.002uM
    BindingDB: IC50=7nM
    10959 2xvn:A (2.35) BS01 KLS 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=112uM
    PDBbind: -logKd/Ki=3.95, IC50=112uM
    10960 2xvn:B (2.35) BS01 KLS 3.2.1.14 GO:0004553 ... Q873Y0 21168763 MOAD: ic50=112uM
    10961 2xwd:A (2.66) BS01 LGS 2.4.1.-
    3.2.1.-
    3.2.1.45
    3.2.1.46    		 GO:0004336 ... P04062 21483943 PDBbind: -logKd/Ki=6.96, Ki=0.11uM
    10962 2xwe:A (2.31) BS01 AMF 2.4.1.-
    3.2.1.-
    3.2.1.45
    3.2.1.46    		 GO:0004336 ... P04062 21483943 MOAD: Ka=2113M^-1
    PDBbind: -logKd/Ki=6.02, Ki=0.95uM
    10963 2xwe:B (2.31) BS01 AMF 2.4.1.-
    3.2.1.-
    3.2.1.45
    3.2.1.46    		 GO:0004336 ... P04062 21483943 MOAD: Ka=2113M^-1
    10964 2xwy:A (2.53) BS01 IB8 2.7.7.48
    3.4.21.98
    3.4.22.-
    3.6.1.15
    3.6.4.13    		 GO:0003723 ... P26663 21141896 PDBbind: -logKd/Ki=5.22, IC50=6uM
    10965 2xx2:A (1.85) BS01 13C ? GO:0005524 ... P02829 21932796 PDBbind: -logKd/Ki=7.30, IC50=0.05uM
    10966 2xx4:A (2.199) BS01 13I ? GO:0005524 ... P02829 21932796 PDBbind: -logKd/Ki=7.10, IC50=0.08uM
    10967 2xx5:A (2.0) BS01 13N ? GO:0005524 ... P02829 21932796 PDBbind: -logKd/Ki=6.70, IC50=0.20uM
    10968 2xxr:A (1.6) BS01 GLU ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=6.55, Ki=280nM
    10969 2xxt:A (1.9) BS01 KAI ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=8.05, Kd=9.0nM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10970 2xxt:B (1.9) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10971 2xxv:A (1.7) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10972 2xxv:B (1.7) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10973 2xxw:A (2.3) BS01 GLU ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=6.41, Ki=390nM
    10974 2xxx:A (2.098) BS01 GLU ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=6.41, Ki=390nM
    10975 2xxy:A (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 PDBbind: -logKd/Ki=7.89, Kd=12.9nM
    BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10976 2xxy:B (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10977 2xxy:C (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10978 2xxy:D (3.0) BS01 KAI ? GO:0015276 ... P42260 21414913 BindingDB: Ki=12.7nM, Kd=39nM, EC50=1800nM
    10979 2xxz:A (1.8) BS01 8XQ 1.14.11.68 N/A O15054 N/A BindingDB: IC50=100nM
    10980 2xxz:B (1.8) BS01 8XQ 1.14.11.68 N/A O15054 N/A BindingDB: IC50=100nM
    10981 2xy9:A (1.97) BS03 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=0.65nM
    PDBbind: -logKd/Ki=9.19, Ki=0.65nM
    BindingDB: Ki=0.65nM
    10982 2xy9:A (1.97) BS04 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=0.65nM
    PDBbind: -logKd/Ki=9.19, Ki=0.65nM
    BindingDB: Ki=0.65nM
    10983 2xya:A (2.4) BS01 7L4 2.7.7.48
    3.4.22.28
    3.4.22.29
    3.6.1.15    		 GO:0004197 ... P04936 21183345 MOAD: Kd=200uM
    10984 2xyd:A (2.15) BS01 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=150nM
    PDBbind: -logKd/Ki=6.82, Ki=150nM
    BindingDB: Ki=0.65nM
    10985 2xyd:B (2.15) BS01 3ES 3.4.15.1 GO:0006508 ... P12821 21352096 MOAD: Ki=150nM
    BindingDB: Ki=0.65nM
    10986 2xye:A (2.0) BS01 CXG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 N/A PDBbind: -logKd/Ki=8.34, Ki=4.6nM
    10987 2xye:B (2.0) BS01 CXG 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 N/A PDBbind: -logKd/Ki=8.34, Ki=4.6nM
    10988 2xyf:A (1.8) BS01 G40 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 N/A PDBbind: -logKd/Ki=8.44, Ki=3.6nM
    10989 2xyf:B (1.8) BS01 G40 2.7.7.-
    2.7.7.49
    2.7.7.7
    3.1.-.-
    3.1.13.2
    3.1.26.13
    3.4.23.16    		 GO:0004190 ... P12499 N/A PDBbind: -logKd/Ki=8.44, Ki=3.6nM
    10990 2xyn:A (2.81) BS01 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 PDBbind: -logKd/Ki=8.40, Kd=4nM
    BindingDB: Kd=4nM
    10991 2xyn:B (2.81) BS01 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10992 2xyn:B (2.81) BS02 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10993 2xyn:B (2.81) BS03 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10994 2xyn:C (2.81) BS01 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10995 2xyn:C (2.81) BS02 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10996 2xyn:C (2.81) BS03 VX6 2.7.10.2 GO:0004672 ... P42684 21417343 BindingDB: Kd=4nM
    10997 2xyr:A (2.5) BS01 SFG 2.1.1.-
    2.1.1.56
    2.1.1.57
    2.7.7.48
    2.7.7.50
    3.1.13.-
    3.4.19.12
    3.4.22.-
    3.4.22.69
    3.6.4.12
    3.6.4.13
    4.6.1.-    		 GO:0004483 ... P0C6X7 21637813 PDBbind: -logKd/Ki=6.13, IC50=0.74uM
    10998 2xys:A (1.909) BS01 SY9 ? GO:0004888 ... Q8WSF8 21468359 MOAD: Ki=38nM
    PDBbind: -logKd/Ki=7.42, Ki=38nM
    10999 2xys:A (1.909) BS02 SY9 ? GO:0004888 ... Q8WSF8 21468359 MOAD: Ki=38nM
    PDBbind: -logKd/Ki=7.42, Ki=38nM
    11000 2xys:B (1.909) BS01 SY9 ? GO:0004888 ... Q8WSF8 21468359 MOAD: Ki=38nM
    PDBbind: -logKd/Ki=7.42, Ki=38nM
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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