Structure of PDB 5t5h Chain e

Receptor sequence

>5t5he (length=245) Species: 5693 (Trypanosoma cruzi) [Search protein sequence]

GKTVLTCRKGNGSIYQVHGHKRLGPAKLRILDYAERHGFMRGVVKTIEHE
PGRGAPLARVEFRHPYKYRRVKELMVAPEGMFTGQSVLCGVKAPLAIGNV
LPLGQITEGCIVCNVEAKVGDRGTIARASGDYCIIISHNHETGRTRLKLP
SGQKKTVPSNCRAMIGIIAGGGRIEKPVLKAGNSFYRFRGKRNCWPKVRG
VARNPVEHPHGGGNHQHIGHPSTVSRHAPPGQKVGLIAARRTGRI

3D structure

PDB

5t5h Structure and assembly model for the Trypanosoma cruzi 60S ribosomal subunit.

Chain

Resolution

2.54 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	e	G2 K3 T4 R9 S14 I15 Y16 H19 H21 K181 A182 G183 F186 Y187 N194 W196 V199 A203 R204 N205 V207 E208	G1 K2 T3 R8 S13 I14 Y15 H18 H20 K180 A181 G182 F185 Y186 N193 W195 V198 A202 R203 N204 V206 E207
BS02	rna	e	G2 T7 C8 K10 G11 N12 G13 Q17 V18 G20 R23 G25 A27 I31 Y34 R37 K46 R54 R64 Y67 K68 Y69 R71 F83 G85 K119 G121 D122 R123 T125 I126 A127 R128 A129 S130 G131 D132 L150 P151 S152 K156 G172 G173 R174 I175 V179 L180 A182 R193 W196 P197 K198 V199 R200 G201 V202 P206 H209 H211 G213 G214 N215 H216 Q217 H218 I219 G220 H221 P222 S223 T224 V225 S226 R227 H228 P230 P231 G232 Q233 K234 V235 G236 L237 I238 A239 A240 R241 R242 T243 G244 R245 I246	G1 T6 C7 K9 G10 N11 G12 Q16 V17 G19 R22 G24 A26 I30 Y33 R36 K45 R53 R63 Y66 K67 Y68 R70 F82 G84 K118 G120 D121 R122 T124 I125 A126 R127 A128 S129 G130 D131 L149 P150 S151 K155 G171 G172 R173 I174 V178 L179 A181 R192 W195 P196 K197 V198 R199 G200 V201 P205 H208 H210 G212 G213 N214 H215 Q216 H217 I218 G219 H220 P221 S222 T223 V224 S225 R226 H227 P229 P230 G231 Q232 K233 V234 G235 L236 I237 A238 A239 R240 R241 T242 G243 R244 I245
BS03	rna	e	H50 P52 Y69 R70 R71 R174 I175 K177 V179 Y187 R188 R190	H49 P51 Y68 R69 R70 R173 I174 K176 V178 Y186 R187 R189

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0002181	cytoplasmic translation
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0022626	cytosolic ribosome
GO:1990904	ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:5t5h, PDBe:5t5h, PDBj:5t5h
PDBsum	5t5h
PubMed	27791004
UniProt	Q4DPQ8

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