Structure of PDB 6zmi Chain SI
Receptor sequence
| >6zmiSI (length=206) Species: 9606 (Homo sapiens) [Search protein sequence] |
| GISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGG NKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNELVRTKTLVKNCI VLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKKRSKKIQKKYDE RKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRK IKARKG |
3D structure
| PDB | 6zmi Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2. | ||
| Chain | SI | ||
| Resolution | 2.6 Å | ||
| 3D structure |
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Enzymatic activity
| Enzyme Commision number | ? |
Interaction with ligand
| Site # |
Ligand | Ligand chain |
Binding residues on receptor (original residue number in PDB) |
Binding residues on receptor (residue number reindexed from 1) |
Binding affinity |
|---|---|---|---|---|---|
| BS01 | rna | SI | R77 I79 R92 K124 Q168 K170 | R76 I78 R91 K123 Q167 K169 | |
| BS02 | rna | SI | G2 R5 H9 K10 R11 R12 K13 T14 G16 Y21 H22 K23 K24 R25 K26 Y27 L29 R31 A33 A34 R42 I43 H44 T45 R47 V48 R49 G50 K53 K54 Y55 R56 N64 S66 T73 R74 K75 S86 K98 N99 R141 K143 I145 K147 K148 Y149 R152 R178 Q181 R184 D186 G187 | G1 R4 H8 K9 R10 R11 K12 T13 G15 Y20 H21 K22 K23 R24 K25 Y26 L28 R30 A32 A33 R41 I42 H43 T44 R46 V47 R48 G49 K52 K53 Y54 R55 N63 S65 T72 R73 K74 S85 K97 N98 R140 K142 I144 K146 K147 Y148 R151 R177 Q180 R183 D185 G186 |
Gene Ontology
| Molecular Function | |
|---|---|
| GO:0003723 | RNA binding |
| GO:0003735 | structural constituent of ribosome |
| GO:0005515 | protein binding |
