Structure of PDB 4gbc Chain D
Receptor sequence
>4gbcD (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTDKT
3D structure
PDB
4gbc
A T3R3 hexamer of the human insulin variant B28Asp.
Chain
D
Resolution
1.778 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
D
G8 V12 E13 Y16 G23 F24 F25 Y26 D28 K29
G8 V12 E13 Y16 G23 F24 F25 Y26 D28 K29
BS02
peptide
D
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30
F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
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Cellular Component
External links
PDB
RCSB:4gbc
,
PDBe:4gbc
,
PDBj:4gbc
PDBsum
4gbc
PubMed
23428413
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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