Structure of PDB 4gbc Chain D

Receptor sequence
>4gbcD (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTDKT
3D structure
PDB4gbc A T3R3 hexamer of the human insulin variant B28Asp.
ChainD
Resolution1.778 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide D G8 V12 E13 Y16 G23 F24 F25 Y26 D28 K29 G8 V12 E13 Y16 G23 F24 F25 Y26 D28 K29
BS02 peptide D F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30 F1 H5 L6 C7 L11 L15 V18 C19 R22 G23 F24 F25 D28 T30
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:4gbc, PDBe:4gbc, PDBj:4gbc
PDBsum4gbc
PubMed23428413
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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