Structure of PDB 4v81 Chain B

Receptor sequence
>4v81B (length=513) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSN
TCMVTNDGATILKSIPLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAEL
LREAEKLIDIHPQTIIEGYRLASAAALDALTKAAVDNSHDKTMFREDLIH
IAKTTLSSKILSQDKDHFAELATNAILRLKGSTNLEHIQIIKILGGKLSD
SFLDEGFILAKKFGNNQPKRIENAKILIANTTLDTDKVKIFGTKFKVDST
AKLAQLEKAEREKMKNKIAKISKFGINTFINRQLIYDYPEQLFTDLGINS
IEHADFEGVERLALVTGGEVVSTFDEPSKCKLGECDVIEEIMLGEQPFLK
FSGCKAGEACTIVLRGATDQTLDEAERSLHDALSVLSQTTKETRTVLGGG
CAEMVMSKAVDTEAQNIDGKKSLAVEAFARALRQLPTILADNAGFDSSEL
VSKLRSSIYNGISTSGLDLNNGTIADMRQLGIVESYKLKRAVVSSASEAA
EVLLRVDNIIRAR
3D structure
PDB4v81 The crystal structure of yeast CCT reveals intrinsic asymmetry of eukaryotic cytosolic chaperonins.
ChainB
Resolution3.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D59 T92 T93 D386
Catalytic site (residue number reindexed from 1) D57 T90 T91 D381
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B L37 G38 D90 G91 T93 S94 L444 L474 I487 L35 G36 D88 G89 T91 S92 L439 L469 I482
BS02 BEF B D59 D90 G91 T92 T93 D386 D57 D88 G89 T90 T91 D381
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006457 protein folding
GO:0051086 chaperone mediated protein folding independent of cofactor
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005832 chaperonin-containing T-complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v81, PDBe:4v81, PDBj:4v81
PDBsum4v81
PubMed21701561
UniProtP39076|TCPB_YEAST T-complex protein 1 subunit beta (Gene Name=CCT2)

[Back to BioLiP]