Structure of PDB 7q9v Chain A

Receptor sequence
>7q9vA (length=133) Species: 5833 (Plasmodium falciparum) [Search protein sequence]
SKNVVIYADGVYDMLHLGHMKQLEQAKKLFENTTLIVGVTSDNETKLFKG
QVVQTLEERTETLKHIRWVDEIISPCPWVVTPEFLEKYKIDYVAHDDIYA
WLKRAGKFKATQRTEGVSTTDLIVRILKNYEDY
3D structure
PDB7q9v Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.15: choline-phosphate cytidylyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GZ6 A D623 W692 D9 W78
BS02 GZ6 A I650 E685 Y702 I36 E71 Y88
BS03 9OI A V766 L769 K770 V124 L127 K128
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0006657 CDP-choline pathway
GO:0009058 biosynthetic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7q9v, PDBe:7q9v, PDBj:7q9v
PDBsum7q9v
PubMed
UniProtQ8IEE9

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