Structure of PDB 4m1z Chain A

Receptor sequence
>4m1zA (length=317) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
DRPWANDYLRIQEAQKFATGAGVTVAVIDTGVNGSPRVPAEPGGDFVDAA
GNGMSDCDAHGTMTAAIIGGRPSPTDGFVGMAPDVRLLSLRQTSVAGSIR
SLARSVVHAANLGAQVINISEAACYKVTRRIDETSLGAAINYAVNVKGAV
IVVAAGNTGQDCSQNPPPDPSVPSDPRGWREVQTIVSPAWYDPLVLTVGS
IGQNGQPSNFSMSGPWVGAAAPGENLTSLGYDGQPVNATPGEDGPVPLNG
TSFSAAYVSGLAALVKQRFPDLTPAQIINRITATARHPGGGVDNYVGAGV
IDPVAALTWEIPDGPEK
3D structure
PDB4m1z The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability.
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D92 H123 N239 S334
Catalytic site (residue number reindexed from 1) D29 H60 N157 S252
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A C120 D121 A122 M126 Y313 P317 V318 N319 A320 P322 P327 C57 D58 A59 M63 Y231 P235 V236 N237 A238 P240 P245
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:4m1z, PDBe:4m1z, PDBj:4m1z
PDBsum4m1z
PubMed24248472
UniProtA0QNL1|MYCP1_MYCS2 Mycosin-1 (Gene Name=mycP1)

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