Structure of PDB 4ia2 Chain A

Receptor sequence
>4ia2A (length=239) Species: 7955 (Danio rerio) [Search protein sequence]
HMLSDEQMQIINSLVEAHHKTYDDSYSDFVRFRPPVRRLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTAEDQIALLKSSAIEIIMLRSNQSFSLEDMS
WSCGGPDFKYCINDVTKAGHTLELLEPLVKFQVGLKKLKLHEEEHVLLMA
ICLLSPDRPGVQDHVRIEALQDRLCDVLQAYIRIQHPGGRLLYAKMIQKL
ADLRSLNEEHSKQYRSLSFQPEHSMQLTPLVLEVFGSEV
3D structure
PDB4ia2 Diastereotopic and deuterium effects in gemini.
ChainA
Resolution2.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I270 K274 R280 A284 I288 K292 L443 E446 I57 K61 R67 A71 I75 K79 L230 E233
BS02 BIV A Y175 L261 V262 S265 R302 S303 S306 W314 V328 H333 L338 L341 H423 Y22 L48 V49 S52 R89 S90 S93 W101 V115 H120 L125 L128 H210
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:4ia2, PDBe:4ia2, PDBj:4ia2
PDBsum4ia2
PubMed23566225
UniProtQ9PTN2|VDRA_DANRE Vitamin D3 receptor A (Gene Name=vdra)

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