Structure of PDB 8b6h Chain Da Binding Site BS05

Receptor Information
>8b6h Chain Da (length=671) Species: 312017 (Tetrahymena thermophila SB210) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NYFYYLDRIKKLFTYLNDLRKHILKKYVYTINHKRIAINYLYFSMVTGLS
GAALATMIRLELAHPGSPFFKGDSLRYLQVVTAHGLIMVFFVVVPILFGG
FANFLIPYHVGSKDVAYPRLNSIGFWIQPCGYILLAKIGFLRPQFWRYYD
KTSFSFPFLEKMKYNQYKEYKNDYLFYLDFLKKEITDDHSFFWKARKVIK
LPQYSVFSFVPLKLMMWKTMINYPESFWYAASRVVQSRRKKVFVTKCSAR
TLTTAGWTFITPFSSNIKYTAVGSQDILILSVVFAGISTTISFTNLLITR
RTLAMPGLRHRRVLMPFVTISIFLTLRMLATITPVLGAAVIMMAFDRHWQ
TTFFEYAYGGDPILSQHLFWFFGHPEVYVLIIPTFGFINMIVPHNNTRRV
ASKHHMIWAIYVMAYMGYLVWGHHMYLVGLDHRSRTMYSTITIMISMPAT
IKVVNWTLSLVNGALKIDLPFLFSMSFLLLFLVAGFTGMWLSHVSLNVSM
HDTFYVVAHFHIMLSGAAMTGIFSGIYYYFNALFGVKYSRMFGYMHLIYY
SGGQWVAFVPLFYLGFSGMPRRIHDYPVVFMGWHSMSTTGHFITLVGIIF
FFLMMFDSHIERRASTSTTLGLPRWYKRISYYIFKIRYLQHTKSKMNGIP
GSTVRLMLINRHFVEYEVYEK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8b6h Chain Da Residue 710 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8b6h Structural basis of mitochondrial membrane bending by the I-II-III 2 -IV 2 supercomplex.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E78 H81 G83 S84 P85 H591
Binding residue
(residue number reindexed from 1)		E61 H64 G66 S67 P68 H574
Annotation score1
Enzymatic activity
Enzyme Commision number 7.1.1.9: cytochrome-c oxidase.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006119 oxidative phosphorylation
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8b6h, PDBe:8b6h, PDBj:8b6h
PDBsum8b6h
PubMed36949187
UniProtQ950Y4

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