Structure of PDB 7mqa Chain SI Binding Site BS04

Receptor Information
>7mqa Chain SI (length=803) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DQKKHRKKNSGPKAAKKKKRLLQDEEDARKRNPKAFAVQSAVRMARSFHR
TQDLKTKKHHIPVVDRTPLEPPPIVVVVMGPPKVGKSTLIQCLIRNFTRQ
KLTEIRGPVTIVSGKKRRLTIIECGCDINMMIDLAKVADLVLMLIDASFG
FEMETFEFLNICQVHGFPKIMGVLTHLDSFKHNKQLKKTKKRLKHRFWTE
VYPGAKLFYLSGMVHGEYQNQEIHNLGRFITVMKFRPLTWQTSHPYILAD
RMEDLTNPEDIRTNIKCDRKVSLYGYLRGAHLKNKSQIHMPGVGDFAVSD
ISFLPDPCALPEQQKKRCLNEKEKLVYAPLSGVGGRQQQAAPNLRKLIYG
HKADSLDCSRFLVEAPHDWDLEEVMNSIRDCFVTESTYFDDLKGEMQKQA
QLNRAEFEDQDDEARVQYEGFRPGMYVRIEIENVPCEFVQNFDPHYPIIL
GGLGNSEGNVGYVQMRLKKHRWYKKILKSRDPIIFSVGWRRFQTIPLYYI
EDHNGRQRLLKYTPQHMHCGAAFWGPITPQGTGFLAIQSVSGIMPDFRIA
ATGVVLDLDKSIKIVKKLKLTGFPYKIFKNTSFIKGMFNSALEVAKFEGA
VIRTVSGIRGQIKKALRAPEGAFRASFEDKLLMSDIVFMRTWYPVSIPAF
YNPVTSLLKPVGEKDTWSGMRTTGQLRLAHGVRLKANKDSLYKPILRQKK
HFNSLHIPKALQKALPFKNKPKTQAKAGKVPKDRRRPAVIREPHERKILA
LLDALSTVHSQKMKKAKEQRHLHNKEHFRAKQKEEEEKLKRQKDLRKKLF
RIQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7mqa Chain SI Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7mqa Nucleolar maturation of the human small subunit processome.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		S96 E132
Binding residue
(residue number reindexed from 1)		S87 E123
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0034511 U3 snoRNA binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0042254 ribosome biogenesis
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7mqa, PDBe:7mqa, PDBj:7mqa
PDBsum7mqa
PubMed34516797
UniProtQ14692|BMS1_HUMAN Ribosome biogenesis protein BMS1 homolog (Gene Name=BMS1)

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