Structure of PDB 8scb Chain jj Binding Site BS03

Receptor Information
>8scb Chain jj (length=578) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETL
CIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGE
VLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQN
YFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQL
DLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLK
AAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFS
VREGINIFLDGYVPTENLRFRDASLVFMYKYPGMKKKMGEFELAIVAGEF
TDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPK
STGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQR
VALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVE
HDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRD
PNNYRPRINKLNSIKDVEQKKSGNYFFL
Ligand information
Ligand IDSF4
InChIInChI=1S/4Fe.4S
InChIKeyLJBDFODJNLIPKO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7[S]12[Fe]3[S]4[Fe]1[S]5[Fe]2[S]3[Fe]45
CACTVS 3.385S1[Fe]S[Fe]1.S2[Fe]S[Fe]2
FormulaFe4 S4
NameIRON/SULFUR CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8scb Chain jj Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8scb Structure and consequences of eRF1 glued to the ribosomal decoding center
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C29 C38 I39 I50 C55 I56 G57 C58 C61
Binding residue
(residue number reindexed from 1)		C25 C34 I35 I46 C51 I52 G53 C54 C57
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0000054 ribosomal subunit export from nucleus
GO:0006413 translational initiation
GO:0006415 translational termination

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:8scb, PDBe:8scb, PDBj:8scb
PDBsum8scb
PubMed38172604
UniProtG1SG72

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