Structure of PDB 2xgq Chain B Binding Site BS03

Receptor Information
>2xgq Chain B (length=511) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRMSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKE
DPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKG
EDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDL
VERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGN
YDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGI
RDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCG
KFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLDA
KVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMSN
KNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISLK
TKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLTK
LSMTITNFDII
Ligand information
Receptor-Ligand Complex Structure
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PDB2xgq Mechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Q55 S58 V392 K393 S394 M395 M396 R426
Binding residue
(residue number reindexed from 1)		Q57 S60 V394 K395 S396 M397 M398 R428
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:2xgq, PDBe:2xgq, PDBj:2xgq
PDBsum2xgq
PubMed21076032
UniProtQ04049|POLH_YEAST DNA polymerase eta (Gene Name=RAD30)

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