Structure of PDB 7p3k Chain n Binding Site BS02

Receptor Information

>7p3k Chain n (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>7p3k Chain b (length=119)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggca

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7p3k Structural basis of l-tryptophan-dependent inhibition of release factor 2 by the TnaC arrest peptide.
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): K3 R15 H29 R30 T31 P32 R33 H34 Y36 S45 V47 Y64 N67 K68 H100 R102
• Binding residue (residue number reindexed from 1): K2 R14 H28 R29 T30 P31 R32 H33 Y35 S44 V46 Y63 N66 K67 H99 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7p3k, PDBe:7p3k, PDBj:7p3k
• PDBsum: 7p3k
• PubMed: 34403461
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)