Structure of PDB 5gag Chain P Binding Site BS02

Receptor Information

>5gag Chain P (length=117) Species: 562 (Escherichia coli)

MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVA
ASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYH
GRVQALADAAREAGLQF

Ligand information

>5gag Chain B (length=120)

ugccuggcggccguagcgcgguggucccaccugaccccaugccgaacuca
gaagugaaacgccguagcgccgaugguaguguggggucuccccaugcgag
aguagggaacugccaggcau

<<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>
>..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>...
....>>...>>>>>>>>>>.

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5gag Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
• Resolution: 3.8 Å
• Binding residue (original residue number in PDB): K3 R15 R25 H29 R30 T31 P32 R33 H34 Y36 G44 S45 V47 E55 K63 Y64 N67 K68 H100 G101 R102
• Binding residue (residue number reindexed from 1): K3 R15 R25 H29 R30 T31 P32 R33 H34 Y36 G44 S45 V47 E55 K63 Y64 N67 K68 H100 G101 R102

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:5gag, PDBe:5gag, PDBj:5gag
• PDBsum: 5gag
• PubMed: 26804923
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)