Structure of PDB 6xwh Chain C Binding Site BS02

Receptor Information
>6xwh Chain C (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6xwh Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		E153 G154 F158 R161 R184 N185 Q188 R191 R209
Binding residue
(residue number reindexed from 1)		E23 G24 F28 R31 R54 N55 Q58 R61 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwh, PDBe:6xwh, PDBj:6xwh
PDBsum6xwh
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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