Structure of PDB 7o80 Chain BP Binding Site BS02

Receptor Information

>7o80 Chain BP (length=159) Species: 9986 (Oryctolagus cuniculus)

VRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDV
TLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESN
AELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILT
EKEQIVPKP

Ligand information

>7o80 Chain B8 (length=156)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7o80 Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): R3 S5 R61 R62 W78 N120 K121 P123 H145
• Binding residue (residue number reindexed from 1): R2 S4 R60 R61 W77 N119 K120 P122 H144

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0015934 large ribosomal subunit
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7o80, PDBe:7o80, PDBj:7o80
• PDBsum: 7o80
• PubMed: 34029205
• UniProt: G1SCJ6|RL17_RABIT Large ribosomal subunit protein uL22 (Gene Name=RPL17)