Structure of PDB 3jam Chain W Binding Site BS01

Receptor Information
>3jam Chain W (length=129) Species: 28985 (Kluyveromyces lactis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLQVMQKHGYIGEFE
YIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIADVEKWTANLLPARQFGY
VILTTSAGIMDHEEAHRKHVSGKILGFVY
Ligand information
>3jam Chain 2 (length=1780) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacauggauaucug
ugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaagag
auguauuuauuagauaaaaaaucaaugucuucggacuccuugaugauuca
uaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaaa
uuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuuc
aacggguaacggggaauaaggguucgauuccggagagggagccugagaaa
cggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccua
auucagggagguagugacaauaaauaacgauacagggcccauucgggucu
uguaauuggaaugaguacaauguaaauaccuuaacgaggaacaacuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaguagcguaua
uuaaaguuguugcaguuaaaaagcucguaguugaacuuugggucugguug
uccggucgguuuuucaaccggaucuuuccuucuggcuaaccuguacuccu
ugugggugcaggcgaaccaggacuuuuacuuugaaaaaauuagaguguuc
aaagcaggcgaaagcucgaauauauuagcauggaauaauggaauaggacg
uuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggga
cggucgggggcaucaguauucaauugucagaggugaaauucuuggauuua
uugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaauc
aagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuua
accauaaacuaugccgacuagggaucgggugguguuuuucuuaugaccca
cucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaugg
ucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagug
gagccugcggcuuaauuugacucaacacggggaaacucaccagguccaga
cacaauaaggauugacagauugagagcucuuucuugauuuuguggguggu
ggugcauggccguucuuaguugguggagugauuugucugcuuaauugcga
uaacgaacgagaccuuaaccuacuaaauaggguugcuggcacuugccggu
ugacucuucuuagagggacuaucgguuucaagccgauggaaguuugaggc
aauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcuac
acugacggagccagcgaguacaaccuuggccgagaggucuggguaaucuu
gugaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagug
aggccucaggauuugcuuagagaagggggcaacuccaucucagagcgaag
aaucuggucaaacuuggucauuuagaggaacuaaaagucguaacaagguu
uccguaggugaaccugcggaaggaucauua
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<.<...<......<<<
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<<...............<<.....<<.
<<.......>>.>>......>>........<<<<<..<<....>>..>>>
>><..<<.<<<<......(((((((.<<<....>>>..............
>>>>>>.....>...<<<<..<<<.....>>>.>>>>..>.>>>...>>>
>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>...
...>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<.<<<..>>>.>...>>>>>>.........<<<....<<<.
....>>>..>>>..>....>.>.....<<<<<<<<<<..........>>>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>
>>>.........<<<[[.....<.<<...<<<.<<....<<<<<<<<<<<
.....<..>.....>>>>>>>>>>>....<<<<<<....<<<<..<<...
....>>..>>>>....>>>>>>...<<<<<.<<.......<<...<....
...>..<<<....>>>....>>......>>.>>..>>>.........<<<
..<<<<<<<<.....))))))).>>>>>>>>.>>>.....>>....<<<<
<<.<<...<<<<..<<<.<<<<<<.<...<<<......>>>......>.>
>>>>.>>>>.......<<....>>...>>>>...>>>>>.>>>...>>>.
..>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>
>>..........<<<.<<.<<<..<<<<<<<<.<<<........>>>>>>
>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<<
<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<<.<<<<<<.
.<<<.<<<<<<......<<........>>..........<<<<<.<....
<<<<<.....<..<<.<............>.>>.>....>>>>>...<<.
<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<......>>>.
..>>.>>>....<<<<<.<<..<<<<..<<<<<<<<<<<<....>>>>>>
.>>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>>.
...>>>.>>>.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>..
...<<<<<<<......<<.....<<<.<<<<....>>>>.>>>....>>.
......>>>>>>>......<....<<<<<<..........>>>>>>....
>.....>>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<.
.<<<<..<...<<<<<<..........................>>>>>>.
..>..>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<
<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3jam Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		T2 R3 T4 V6 N12 N16 K19 K22 R28 S31 K32 H56 R57 S58 K60 K71 V74 I75 S76 R78 N80 K82 I83 K88 W89 T105 T106 S107 I110 R118 K119 H120 S122 F128 Y130
Binding residue
(residue number reindexed from 1)		T1 R2 T3 V5 N11 N15 K18 K21 R27 S30 K31 H55 R56 S57 K59 K70 V73 I74 S75 R77 N79 K81 I82 K87 W88 T104 T105 S106 I109 R117 K118 H119 S121 F127 Y129
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3jam, PDBe:3jam, PDBj:3jam
PDBsum3jam
PubMed26212456
UniProtQ6CW21|RS22_KLULA Small ribosomal subunit protein uS8 (Gene Name=RPS22)

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