Structure of PDB 8rxx Chain SA Binding Site BS01 |
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| >8rxx Chain S1 (length=1836)
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gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcagcaggaaucugcgcauggcucauuaaa
ucagacguaaucugccgcaaaaaucuugcggccgcaaaauuggauaacuu
ggcgaaacgccaagcuaauacaugaaccaaccggguguucuccacgugag
acgcccagcgaaugaaugacaguaaaaccaaugccuugcaguaacaccca
gcaguguugacucaauucauuccgugcgaaagccggcuuguuccggcguc
uuuugacgaacaacugcccuaucagcuggugauggccguguaguggacug
ccauggcguugacgggagcgggggauuaggguucgauuccggagagggag
ccugagaaauagcuaccacuucuacggagggcagcaggcgcgcaaauugc
ccaaugucaaaacaaaacgaugaggcagcgaaaagaaauagaguuguuug
ucauuucaaugggggauauuuaaacccauccaauaucgaguaacaauugg
aggacaagucuggugccagcacccgcgguaauuccagcuccaaaagcgua
uauuaaugcuguugcuguuaaaggguucguaguugaacugugggcugugc
agggcccuugcagcccgugaaaagaaacaagaaacacgggagugggucgc
augucaugcaugccagggggcguccgugauuuuuacugugacuaaagaag
cgugacuaaagcagucauuugacuugaauuagaaagcaugggauaacaaa
ggagcagccucuaggcuaccguuucggcuuuuguuguuuuuaaaggucua
uuggagauuauggagcuguuucccacggugugacggccucuaggaaugaa
ggaggguaguucgggggagaacguacuggggcgucagaggugaaauucuu
agaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuuc
cucaaucaagaaccaaaguguggagaucgaagaugauuagaaaccauugu
aguccacacugcaaacgaugacacccaugaauuggggauacuuaguaucu
uuacgggaauauccucagcacgcacgcgaaagcuuugagguuacagucuc
aggggggaguacguucgcaagagugaaacuuaaagaaauugacggaaugg
caccacaagacguggagcgugcgguuuaauuugacucaacacggggaacu
uuaccagauccggacaggaugagauugacagauugaguguucuuucucga
uucccugaaugguggugcauggccgcuuauggucgguggagugauuuguu
ugguugauuccgucaacggacgagauccaagcugcccaguagaauucaga
auugcccauaggauagcgcauucggucgaauucuucucugcgggauuccu
uuguaauugcacaaggugaaauuuugggcaacagcaggucugugaugcuc
cucaauguucugggcgacacgcgcacuacaaugucagugagaacaagaaa
acgaaccuacuugaucaaaagaguggggaaaccccggaaucacauagacc
cacuugggaccgaggauugcaauuuggucgcgcaacgaggaaugucucgu
aggcgcagcucaucaaacugugccgauuacgucccugccauuuguacaca
ccgcccgucguuguuuccgaugauggugcaauacaggugaucggacaggc
gcccgaaaguucaccgauauuucuucaauagaggaagcaaaagucguaac
aagguagcuguaggggaaccugcagcugggacauuu |
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<<<..........<<<
.<<<..<<....<<....<<<<.>>>>...>>.>>......<<.......
.<<<..<<..<<...<<.<<.....<<<<<..>>>>>...<<.....<<<
<<<.....>>>>>>......>>..........<<<<<.<<<<.....>>>
>>>>>>.<<<<<<<<<<.....(((((.((((<<...>>...........
..............>>>>>>>>...>>....<<<<<......>>>>>...
>>.>>..>>>>..>>>.<<<....<<<....<<<<<.<<.......>>.>
>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<.<<
<..........>>>.>>.<<<<....>>>>...>>>>>>.........<<
<....<<<..........>>>..>>>.......>>>....<<<.<<....
.>>.>>>.....<<<<............>>>.....>.........<<<<
<((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>
>>>>>.........<<<[[.....<<<<...<<<.......<...<<...
.<..>...>>...>..................<...............<<
<<.......>>>>.............>.....<<<<<<<<.......<<.
..<.......>..<<<....>>>.....>>......>>>>>..>>>....
.......<<..<<<<<<.<<.....>>.<...)))).)))))>.>>>>>>
..>>.......<<<<<<<.<.<<...>>.>...>>>.>>>>.........
...<<<<<..<<...<<<<<<<<<.<<<<.<<<...<<<......>>>..
....>>>.>>>.>>>>.......<<....>>.>>>>>>..>>.>>>.>>.
...>>>...>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>..
.>>>>>>>>>.........<<<.<<..<<..<<<<<<<........<<..
........>>.>>>>>>>..>>...<<..]]>>.....>>.....>>>.>
>>.<<<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<
<<..<<.<<<<<<..<<.<<<<<<<......<<........>>.......
...<<<<<.<....<<<<........<<.<<<........>>>.>>....
...>>>>...<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...
<<<......>>>...>>.>>>....<<<<<.<<<<.....<<<<<<<.<<
<<.................>>>>....>>>>>>>.....>>>>....<<<
<.<<......>>>>>>.......>>>>>....>>>.>>>.....>>>>>>
>.....>.>>>>>...>>.>>>>>.>>.....<<<.<<<<......<...
.....<<<<<<<........>>>>>>>....>.......>>>>...>>>.
..........<<<..<........>..>>>...........>>>>>>...
.<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<.<<<<<<<<..<<.<<<.<.<<<<..<<<<<.....<.<<.
.>>.>.....>>>>>..>>>>.>.>>>.>>..>>>>>>>>..>.>>...>
.....<<<<<<<<<....>>>>>>>>>......... |
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| PDB | 8rxx Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. |
| Resolution | 2.97 Å |
Binding residue
(original residue number in PDB) | A2 K5 N6 R8 I9 S10 K11 T23 R26 K27 R55 V65 H103 L116 K118 W119 R138 F140 Q148 N150 Q151 Q152 S153 R154 Y157 K159 Q160 R161 K164 W165 R167 M168 R169 K172 R202 N204 P205 I206 |
Binding residue
(residue number reindexed from 1) | A1 K4 N5 R7 I8 S9 K10 T15 R18 K19 R47 V57 H95 L108 K110 W111 R130 F132 Q140 N142 Q143 Q144 S145 R146 Y149 K151 Q152 R153 K156 W157 R159 M160 R161 K164 R194 N196 P197 I198 |
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| Enzyme Commision number |
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