Structure of PDB 8y6f Chain J Binding Site BS01

Receptor Information
>8y6f Chain J (length=171) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKY
FLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKEPDCDDWESGQNAMECAL
HLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTN
LRKMGAPSGLAEYLFDKHTLG
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain8y6f Chain J Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8y6f Engineered protein cages with enhanced extracellular drug release for elevated antitumor efficacy.
Resolution2.01 Å
Binding residue
(original residue number in PDB)		E28 E63 H66
Binding residue
(residue number reindexed from 1)		E23 E58 H61
Annotation score5
External links
PDB RCSB:8y6f, PDBe:8y6f, PDBj:8y6f
PDBsum8y6f
PubMed38604418
UniProtP02794|FRIH_HUMAN Ferritin heavy chain (Gene Name=FTH1)

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