Structure of PDB 8d8l Chain G Binding Site BS01

Receptor Information

>8d8l Chain G (length=146) Species: 4932 (Saccharomyces cerevisiae)

PTAEQLAQWEALKSVPIPPRKNATLDHITNMIMRHGKKEKAQTILSRALY
LVYCQTRQDPIQALEKSLDELAPLMMTKTVIPVPLNKRQRNRIAWNWIVQ
SANQRVSSDFAVRLGEELTAIAKGTSSAFEKRDQIHKTAIAHRAYI

Ligand information

>8d8l Chain a (length=1506)

uaagaauaugauguugguucagauuaagcgcuaaauaaggacaugacaca
ugcgaaucauacguuuauuauugagauaauaaauaugugguguaaacgug
aguaauuuuauuaggaauuaaugaacuauagaauaagcuaaauacuuaau
auuauauaaaaauaauuuauauaauaaaaaggauauauauauauauauuu
aucuauagucaagccaauaaugguuuagguaguagguuuauuaagaguua
aaccuagccaacgauccauaaucgauaaugaaaguuagaacgaucacguu
gacucugaaauauagucaauaucuauaagauacagcagugaggaauauug
gacaaugaucgaaagauugauccaguuacuuauuaggaugauauauauau
auauauaaauugauuaaaaauaaaauccauaaauaauuaaaauaaugaua
uuaauuaccauauauuuauauggauauauauauauuuuaauaguccugac
uaauauuugugccagcagucgcgguaacacaaagagggcgagcguuaauc
auaaugguuuaaaggauccguagaaugaauuauauauaauuuagaguuaa
uaaaauauaauuaaagaauuauaauaguaaagaugaaauaauaauaauaa
uuauaagacuaauauaugugaaaauauuaauuaaauauuaacugacauug
agggauuaaaacuagaguagcgaaacggauucgauacccguguaguucua
guaguaaacuaugaauacaauuauuuauaauauauauauaaauaauaaau
gaaaaugaaaguauuccaccugaagaguacguuagcaauaaugaaacuca
aaacaauagacgguuacagacuuaagcaguggagcauguuauuuaauucg
auaauccacgacuaaccuuaccauauuuugaauauuauaauaauuauaau
uauuauauuacaggcguuacauuguugucuuuaguucgugcugcaaaguu
uuagauuaaguucauaaacgaacaaaacuccauauauauaauuuuaauua
uauauaauuuuauauuauuuauuaauauaaagaaaggaauuaagacaaau
cauaaugauccuuauaauauggguaauagacgugcuauaauaaaaugaua
auaaaauuauauaaaauauauuuaauuauauuuaauuaauaauauaaaac
auuuuaauuuuuaauauauuuuuuuauuauaauaugaauuauaaucugaa
auucgauuauaugaaaaaagaauugcuaguaauacguaaauuaguauguu
acggugaauauucuaacuguuucgcacuaaucacucaucacgcguugaaa
cauauuauuaucuuauuauuuauauaauauuuuuuaauaaauauuauuaa
uuuauauuuauuuauaucagaaauaauaugaauuaaugcgaaguugaaau
acaguuaccguaggggaaccugcggugggcuuauaaauaucuuaaauauu
cuuaca

...<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<......<<<.
<<<..<<<..<<<<<<<<<<<<..>>>>>>>>>>..>>>>>.....<<<.
.......<<<<<.<<.........<<<<<<<<.<<<<.......>>>>..
.<<<<<<<<<.....>>>>>>>>>......<<<<<<<<<..>>>>>>>>>
.>>>>>>>>....>>>>>>><<<....<<<..<<<<<<<<........>>
>>>>>>>>>......>>>..<<<<.<<<<....>>>>...>>>>.>>><<
<<<<.........>>>>>><<<<.....>>>>..>>>>>>.........<
<<...<<<<<....>>>>.>>>>...>.>>>>>>.<<<<..<<<<<<...
.>>>>>>..<<......>>.....>>>>..<<<<<<<<............
..>>>>><<<<<<<..>>>>>>>.<<<<..>>>>.>>>....<<<<<(((
.....<<<<.....<<.)))>>.......>>>>.>>>>>..>>>>>>>>>
.....<<<((.....<<<<...<.<<.<<<<<<..>>>>>>...<<<<<<
<<.....<<<<<<<<<..<<<<<<<....<...........>.......>
>>>>>>..>>.......<<....>>.>>>>>>>..>>>>>>>>...>>>.
..>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>
>>..........<<<<<<.<<<<<<<<<<<<..>>.>>>>>>>>>>..<<
..))>>....>>>>>>.>>>.<<.......<<<<....>>>>.....>>.
.)))).]<<.<<...<<<<......<<<<<..<<<<<<<<<<........
....................<<<<<<<.....<<.<<<<<<<<<<..>>>
>>>>>>>.>>.<<<.<<..<<<<<<<<<<<<..<<<<<<<<<....>>>.
...<<......>>....>>>>>>.....<<<.<<<<<<<<........>>
>>>>>>..<<<<<<<<<.....>>>>>>>>>....>>>...>>>>>>>..
..>>>>>>>>>>...>>>>>>>...>>.>>>>>>>>.....<<<<<<...
.....<<<..<<..<<<<<<......>>>>>>..>>....>>>......>
>>>>>......<<<<<.<....>.>>>>>.....<....<<<<<<<....
....>>>>>>>....>.....>>>>>.....<<.<<<<<.........>>
>>>>>...........>>>>..>>..>>....<.<<<.<.<<<<<<<<..
<<<<<<<<<.<<<...<<<..<<<.<<<<<...<<<<<<<...>>>>>>>
...>>>>>>>>..>>>..>>>>>>>>>>>>..>>>>>>>>..>.>>.>.>
.....<<<<<<<<<....>>>>>>>>>.......................
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8d8l Principles of mitoribosomal small subunit assembly in eukaryotes.
• Resolution: 2.6 Å
• Binding residue (original residue number in PDB): H116 N119 M122 R123 H124 G125 K126 K127 E128 K129 R186 Q187 R190 N201 S206 D207 F208 R211
• Binding residue (residue number reindexed from 1): H27 N30 M33 R34 H35 G36 K37 K38 E39 K40 R88 Q89 R92 N103 S108 D109 F110 R113

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003729 mRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000028 ribosomal small subunit assembly
• GO:0006412 translation
• GO:0032543 mitochondrial translation

Cellular Component

• GO:0005739 mitochondrion
• GO:0005743 mitochondrial inner membrane
• GO:0005763 mitochondrial small ribosomal subunit
• GO:0005840 ribosome
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:8d8l, PDBe:8d8l, PDBj:8d8l
• PDBsum: 8d8l
• PubMed: 36482135
• UniProt: P47150|RT07_YEAST Small ribosomal subunit protein uS7m (Gene Name=RSM7)