Structure of PDB 4c31 Chain E Binding Site BS01

Receptor Information
>4c31 Chain E (length=92) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DTAQLKSQIQQYLVESGNYELISNELKARLLQEGWVDKVKDLTKSEMNIN
ESTNFTQILSTVEPKALEMVSDSTRETVLKQIREFLEEIVDT
Ligand information
>4c31 Chain F (length=14) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ESIVLPTVGFDFIK
Receptor-Ligand Complex Structure
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PDB4c31 Structural Basis for Binding the Trex2 Complex to Nuclear Pores, Gal1 Localisation and Mrna Export.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K9 Q13 V17 Y22 E23
Binding residue
(residue number reindexed from 1)		K6 Q10 V14 Y19 E20
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0000973 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0006406 mRNA export from nucleus
GO:0015031 protein transport
GO:0016973 poly(A)+ mRNA export from nucleus
GO:0032880 regulation of protein localization
GO:0045893 positive regulation of DNA-templated transcription
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051028 mRNA transport
GO:0071028 nuclear mRNA surveillance
Cellular Component
GO:0000124 SAGA complex
GO:0000932 P-body
GO:0005634 nucleus
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0046695 SLIK (SAGA-like) complex
GO:0070390 transcription export complex 2
GO:0071819 DUBm complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4c31, PDBe:4c31, PDBj:4c31
PDBsum4c31
PubMed24705649
UniProtQ6WNK7|SUS1_YEAST Transcription and mRNA export factor SUS1 (Gene Name=SUS1)

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