Structure of PDB 3w13 Chain E Binding Site BS01
Receptor Information
>3w13 Chain E (length=288) Species:
9606
(Homo sapiens) [
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GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKL
IMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKEL
GLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEE
CGDICNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSEC
LGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDL
HHKQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPK
Ligand information
>3w13 Chain B (length=15) Species:
9606
(Homo sapiens) [
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CGSHLVEALYLVCGE
Receptor-Ligand Complex Structure
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PDB
3w13
How insulin engages its primary binding site on the insulin receptor
Resolution
4.303 Å
Binding residue
(original residue number in PDB)
F39 E97
Binding residue
(residue number reindexed from 1)
F35 E93
Enzymatic activity
Enzyme Commision number
2.7.10.1
: receptor protein-tyrosine kinase.
External links
PDB
RCSB:3w13
,
PDBe:3w13
,
PDBj:3w13
PDBsum
3w13
PubMed
23302862
UniProt
P06213
|INSR_HUMAN Insulin receptor (Gene Name=INSR)
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