Structure of PDB 7pub Chain DA Binding Site BS01

Receptor Information
>7pub Chain DA (length=1552) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFKYATKLQHDEMRQPYYIHEKRYGIFSNERNIAKARRGLPFITPLYTKH
MNLWDTDTDASNNRFFRGYYYGQRELHQLLGRPHSLEATNADGSNDLSTY
EANTSQLYKGIPRPAITNLHYEPAWRYTLYQAGAHGAQLSNPRSPFTAKV
LGDELMQVRDIKSVEHCKAWFDRLQYLINLHYEAVGDIGEFKSRHTRHVH
EFFVAFHDALSSLDFRDTYLFDQFKAVRPPELSDLFGIFLEMEANYVHED
YCPRCSLPYSTTRYCGEGDVDTPFRKHRGRWAPHQKWGREWYDVVARRAE
ALWYRATEDPYFGTPQHTQRQAEALLKVYVQAKQRGKAIDFMNKLRGSVE
YLTGDITITTVMQESYDALLDTTPHPHLLTNGFTLESDAAKYTGEVNKAP
LSPLQFRIDMEMNKYRRQQKEEGVVRVPPALWRLDTSAIVPYKVDSKTRR
IVNWREVKEGIEKSFLSVGLPKEAYTGNEWREMLYLHDVIANREAKAAVL
EQQQKLDREKLKARERASLKGEKSSNSASNGIGIIFPDKDGYQVFFVDEA
SLRPFGIGASGTLFKAVARVYPSPAAVPYDDPVHGKQFLIDTTDETCHLF
GGFEHGDRLLLRAKSEEEVIVMGVSTEGSDAERMLCAMHVDTGKQRERGI
VFLGTDCIDIRERWESVRYAASAYVKGRVTLLESQRTAREEFMGQVVGIR
DGVLFVQWRLLKGGGSVLDRSVAVPIGDSTQVRELFVETKVLGVEPLQSP
PSWRTPFRNDFAEERLKELQRAPFKREKYVSLIQGKYTPKVKKFGYTQHT
TVDDFETKEYKDRLLSKQFFQNPQAFEVVPDRNERSVQFGGKWEYQRTHG
LPTVDRNELENGWSEVEPISDGEMKVIEQALRDISGPRPGNFVKPPSKTK
SLQLSESWWEPLGYGWEQHNEEQKALCDVTEQRLIDGSNLPFGGKLPPFG
TSYGMGERMRAIIEDYSKGFGLGPHGHSPTHDTIHYNTLNAEGERVRDLG
YTDALGRLFSEKLGDRDVHQWAVESCADGEADVRQLLLSLHEWRERGRPP
SLLLANVLSKYLEEEIAAFNKGIPENAPKLQLETSDGTLAHSGSGGSRSG
TMWADVDPTTFALHQASQSTRSTRCDEPFILHLVKRAKLGECVTNFTDTA
YIAHLESSVINEFHLALTKLVGKGISPTLLAQKTGQLHRGSVRVGGNVVP
FVKSRELSRLLERMGLTSESIAVITRGLANCPEQESVGDDFAVPVSLILS
WDQNEDKMVVHVLEELSLRNDGLVMDIQYAIRENKKNRRLRWEFVTTLLP
VFGGNEAKVEQLYSDYCDGKYVPNITVAVEAFIAFLHNATQHPETYSASD
YFDIDDGKSSTASGTGDQPSAGQYTTLKLLDPLEGPFVFDNVKVEYIQTV
ERFRRHGIRAGPVMAPATGFIAANCKSLNYFTRRQEEVVYVTNDSDQGLR
RSLENSAYHKTIAANPALQYLLKARRGAALVETFNRFFYRTMPMLNFYQN
VLKHYSETIQPLRQAAKSSTRGLARALESERSAAMEEFRRNSERYWRNII
EG
Ligand information
>7pub Chain CA (length=621) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaaauuauggucaauuguuaguauucauauuaauuuuuuuaaauguuuua
ucauuuuauaaagguuuauuuuugaaagauuuuuuguauaaaauuuuagg
aauaguuaauaauaauuuauaauuuugauuagauuguuuuguuaaugcua
uuagauggguguggaaaaauaaaaaaaauaauuaauauauaucaauaaua
aauuaaauuaaucuauuagucagaaauggaugccagccguugcgguaauu
ucuaugcuuuuaaauauuauacaauuaucauauuaaauuguuaagugcug
auuuaaccaauaaaaauauaaauaauuuuuauuuguuuuuaaacaccauu
agguauaugcaaauauaaaauuauaguaauuauaaauuauauuauauuau
auuuauucauauaauuaauaggauaauauuuguaguuuuugauaccauga
uaaggauuauaaauugaaaguguuaauaucauaaucaaaauuuauuauuu
auauuaaauauguauguguagauaaaauaagaaauuaaaaagguauuguu
gcccaccaauuuuuauaauaaaaauaacgugcaguaauuaauauauuuau
aaaaauauauuuuuuuuuuuu
....................<<<.......<<<<<<............<.
..>..........................................<....
.<<...<<<.......>>>..>>........>........<<....>>..
..................................................
.................<<<.....<<<<<.....<<....>>.......
>>>>>>>>....>>.>>>>...............................
..................................................
..............................>>>....<............
.<<<<<............................................
..................................................
.....................>>>>>..................>.....
<<.<<<..<<<<<<.....>>>>>>...>>>..>>....<<<<<<<<<..
..>>>>>>>>>..........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7pub Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
Resolution3.7 Å
Binding residue
(original residue number in PDB)
F41 K42 K46 Q48 K74 A75 R76 L79 F81 V309 R314 H316 R317 G318 R319
Binding residue
(residue number reindexed from 1)
F2 K3 K7 Q9 K35 A36 R37 L40 F42 V270 R275 H277 R278 G279 R280
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005763 mitochondrial small ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:7pub, PDBe:7pub, PDBj:7pub
PDBsum7pub
PubMed35042777
UniProtQ57UJ2

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