Structure of PDB 7ucj Chain D Binding Site BS01 |
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| >7ucj Chain 5 (length=3499)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggaaaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggaaau
guggcguacggaagacccacuccccggcgccggggggcccaaguccuucu
gaucgaggcccagcccguggacggugugaggccgguagcggcccccggcg
cgccgggcccgggucuucccggagucggguugcuugggaaugcagcccaa
agcgggugguaaacuccaucuaaggcuaaauaccggcacgagaccgauag
ucaacaaguaccguaagggaaaguugaaaagaacuuugaagagagaguuc
aagagggcgugaaaccguuaagagguaaacgggugggguccgcgcagucc
gcccggaggauucaacccggcggccgguccggccgugccggcggggcgga
ucucccgcucccgucggcgggggaccgccccccggccggcgaccggccgc
cgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccgggacg
gcugggaaggccccggcggggaagguggcccgggggccccggguguuaca
gccccgccccggcagcagcagcucgccgaaucccggggccgagggagcga
gacccgugccgccgcgcucuccccccugggggggccgggccaccccuccc
acggcgcgaccgcuggggcggacuguccagugcgccccgggcgggucgcg
ccgucgggcccgggggccacggcgucccccgcgagcgcacggggucggcg
gcgaugucggcuacccacccgacccgucuugaaacacggaccaaggaguc
uaacacgugcgcgagucgggggcuacgaaagccgccguggcgcaaugaag
gugaaggccggcggcgccgccggccgaggugggaucccgaggccuuccag
uccgccgagggcgcaccaccggcccgucucgcccgccgcgccggggaggu
ggagcacgagcgcacguguuaggacccgaaagauggugaacuaugccugg
gcagggcgaagccagaggaaacucugguggagguccguagcgguccugac
gugcgaaucggucguccgaccuggguauaggggcgaaagacuaaucgaac
caucuaguagcugguucccuccaaaguuucccucaggauagcuggcgcuc
uccgcaguuuuauccgguaaagcgaaugauuagaggucuuggggccgaaa
cgaucucaaccuauucucaaacuuuaaauggguaagaagcccggcucgcu
gguguggagccgggcguggaaugcgagugccuagugggccacuuuuggua
agcagaacuggcgcugcgggaugaaccgaacgccggguuaaggcgcccga
ugccgacgcucaucagaccccagaaaagguguugguugauauagacagca
ggaccugccgaaucaacuagcccugaaaauggauggcgcuggagcgucgg
gcccauacccggccgucgcuggcagucggcagagcgagaaagagaguggc
gcggacgcuacgccgcgacgaguaggagggccgcugcggugagccuugaa
gccuagggcgcgggcccggguggagccgccgcaggugcagaucuuggugg
uaguagcaaauauucaaacgagaacuuugaaggccgaaguggagaagggu
uccaugugaacagcaguugaacaugggucagucgguccugagagaugggc
gagcgccguuccgaagggacgggcgauggccuccguugcccucagccgau
cgaaagggagucggguucagauccccgaauccggaguggcggagaugggc
gccgcgaggcguccagugcgguaacgcgaccgaucccggagaagccggcg
ggagccccggggagaguucucuuuucuuugugaagggcagggcgcccugg
aauggguucgccccgagagaggggcccgugccuuggaaagcgucgcgguu
ccggcggcguccggugagcucucgcuggcccuugaaaauccgggggagag
gguguaaaucucgcgccgggccguacccauauccgcagcaggucuccaag
gugaacagccucuggcauguuggaacaauguagguaagggaagucggcaa
gccggauccguaacuucgggauaaggauuggcucuaagggcuggcagccg
acuuagaacuggugcggaccaggggaauccgacuguuuaauuaaaacaaa
gcaucgcgaaggcccgcggcggguguugacgcgaugugauuucugcccag
ugcucugaaugucaaagugaagaaauucaaugaagcgcggguaaacggcg
ggaguaacuaugacucucuuaagguagccaaaugccucgucaucuaauua
gugacgcgcaugaauggaugaacgagauucccacugucccuaccuacuau
ccagcgaaaccacagccaagggaacgggcuuggcggaaucagcggggaaa
gaagacccuguugagcuugacucuagucuggcacggugaagagacaugau
cguuuuuucacugacccggugaggcgggggggcgagccgggcucucgcuu
cuggcgccaagcgcccggccggccgggcgcgacccgcuccggggacagug
ccagguggggaguuugacuggggcgguacaccugucaaacgguaacgcag
guguccuaaggcgagcucagggaggacagaaaccucccguggagcagaag
ggcaaaagcucgcuugaucuugauuuucaguacgaauacagaccgugaaa
gcggggccucacgauccuucugaccuuuuggguuuuaagcaggagguguc
agaaaaguuaccacagggauaacuggcuuguggcggccaagcguucauag
cgacgucgcuuuuugauccuucgaugucggcucuuccuaucauugugaag
cagaauucaccaagcguuggauuguucacccacuaauagggaacgugagc
uggguuuagaccgucgugagacagguuaguuuuacccuacugaugaugug
uuguugccaugguaauccugcucaguacgagaggaaccgcagguucagac
auuugguguaugugcuuggcugaggagccaauggggcgaagcuaccaucu
gugggauuaugacugaacgccucuaagucagaaucccgcccaggcggaac
gauagcgccggagccucgguuggccucggauagccggucccccgccgggg
uccggugcggagagcccuucgucccgggaaacggggcggccggaaagggg
gccgcccucucgcccgucacgcaccgcacguucguggggaaccuggcgcu
aaaccauucguagacgaccugcuucugggucgggguuucguacguagcag
agcagcugcugcgaucuauugaaagucagcccucgacacaaggguuugu |
.........................<<<<<<.....<<....>>......
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>>>>>>..[[[..<<<<<...<<<<<<<<<<.....>>>>>>.>>>>...
..>>>>>..<<<<<<<<<....<<<<<<<<..<<<<<<<<....<<<<..
....>>>>.....((......<<<.....))>>>...>.>>>>>>>...>
>>>>>>>...>>>>>>>>>.......<<<<<<<........>>>>>>>..
...(((((..<<<<<<)))))..]]]........................
..........<<....>>...............<<<......>>>.....
.............................<<<<<<<<..<<<.<<...<<
<<<<<<.<<<.....<<<<<<<<<....<<<<<<<.<<<<<.<<<<<<<.
<<<<<<<<<......>>>>>>>>>>>>>>>>>>>>>>>>>...>>>..>>
>>>>>>>......>>>.>>>.>>>>>...<<<<<<<.<<<<<<<<<<<<<
<<...<<..<<<..<<<<<<<......<<<<<<<<.>>>>>>>>......
.>>>>>>>..>>>.........>>>>>>..>>>>>>>>>>>.....<<..
...{.>>......<<<<<<.<<<<<<..>>>>>>.<<<<<<..<<<.<<<
<<<<<<<<<<<<<<<<<<<<.<<<<..>>>>.>>>>>>.>>>.>>>>>>>
>>>>.>>>...>>>>>>>.>>...........>>>>>>......>>.>>>
>>...>>>>>...>>>>>>>>..<<<<........>>>><<<<<<....<
<<<<<<<<<<<<..<<<...<<<<.....>>>>.....>>>...<<....
>>...<<<<<<<<<..>>>>>>>>>..<<<<<...<<<..<<<...(((.
[[.>>>..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>
>>.>>....>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<<<
<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<.
.......>>>>.>>>....>>>>>>>>>...<<.......>>......>>
>>>>...>..>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<
...<<<.<<<<<<<<<...<<<....<<<..<.<<<..<<<<.<......
...>.>>>>>>>.>..>>>..>.>>...>>>>>>>...<<<<<<<<<.<.
.....>>>>>>>>>>....>>>>>>>>>>>>..>>..<<<<.<<<<<...
..>>>>>.>>>>....<<<......>>>...<<<<<<<...<<<(((...
....<<<<<.....<<..........<<<.<<<<<<<<<<.......<<<
<<.>>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>..
>>>...>>>>>>><<<<<<.<<<........}...........]].))).
...........>>>>>>>>>....>>>>>>.<.<<<<<<<<.<<......
<<<<.<<<<....>>>>>>>>...>>>>>>>>>>..>.....>>>>>><<
<....<<.....<<<<<<.......>>>>>>.<<<.....<<<<<.<<..
.<<<<<<...<<.....>>.>>>>>>....((<<<<<<...<<....<<<
....>>>..........<<.<<<<<<<<<...>>>>>>>>>>>......>
>....>>>..<<<<<........>>>>>))<<<<....<<<<<..<<<<<
<<<....>>>>>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<
<<<<<<<<<<<<<<<<..{{{..>>>>>>....<<<<<.<<<<.<<<<..
...<<<.....>>>.....>>>>>>>>..>>>>>.....<<<<<<<....
...>>>>>>>>>>>.>.>>>>>>>>>>>>.........>>>>>>>..>..
........>>.>>>.>>>>.>>>..>>.....<<......>>>>>>>.<<
<<.....>>>>..>>>....<<<<.....<<<<<<<.<<.........<.
....<<<<<.....<..>......>>>>><<.<<<<<<<<<<<.>>>>>.
.>>>>>>.>>............<<<<<<<<<..<<<.........>>>..
<<<<<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<
<<<<<.....<<....<<<<<....>>>>.>...>>..>>>>..>>>>><
<<<<<.......>>>>>>........<...........<<<<<.......
>>>>>.....>.....>>....>>.>>>>>>>..>..>>.>>>>>>>..>
>>>>>...>>>....<<<<<........>>>>>....[[[[[..{{{.{{
......[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<<<<<.....
.>>>>>>>>>>...<<<<<.....<<<<..<<.<<<<<>>.>>>>>....
..........<<<<<<<<<..>>>>>>>>>..>>>>..>>>>>....>>>
>>>>>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>
>>..<<...<<<<<<<...<<<<<<.......>>>>>>.....<<.[.((
(>>....>>>>>>>...<<<..<<<<.......>>>>..>>>.<<<....
>>>.>>)))]......((((((..(((..>>>>>>.))))))))).....
.....]]]]..}}]]]].......<<.<.<.<<<<<<...<<.......>
>...>>>>>>...>>.>.>.......<<<<<.<<<<<<..<.<.<<<<<.
.....>>>>>...>.>.<<<.........>>>.....>>>>>..>...>>
>.>>....<<<<<<<....>>>.>>>>....}}..}}}.]]]]].....<
<<<<<.<..<<<..<.<<<<<.................>>>>>.><<<<.
...<<<<....<<.<<<<<<<}}}.>>>>>..>>.>>...>>>>...>>>
><<<<<...<<<<<...........>>>>>...>>>>>.>>>...>.>>>
>>>.<<<<<<<..<<<<....<<<........<<<<<..<<<<<.>>>>>
.>>>>>.......>>>...<<<..<<<<....<<<<<<<<<........>
>>>>>.>>>...>>>>..>>>..............>>>>..>>.>>>>>.
<<<<<.<.............>....<<.<<<<<<<.<<.....<<<<.<.
.<<<<<.>>>>>..>>>>>....>>....>>>>.>>>.>>..>>>>>.. |
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| PDB | 7ucj Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine. |
| Resolution | 3.1 Å |
Binding residue
(original residue number in PDB) | F3 V4 K5 K8 K10 Y12 K14 R15 Y16 Q17 K19 R23 T28 Y31 L36 K43 Y44 K48 F113 M115 G140 A141 F142 Y145 L146 A148 L150 R152 T153 H175 S176 R179 S272 Q275 D278 R279 Q282 S286 R289 A290 |
Binding residue
(residue number reindexed from 1) | F1 V2 K3 K6 K8 Y10 K12 R13 Y14 Q15 K17 R21 T26 Y29 L34 K41 Y42 K46 F111 M113 G138 A139 F140 Y143 L144 A146 L148 R150 T151 H173 S174 R177 S270 Q273 D276 R277 Q280 S284 R287 A288 |
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| Enzyme Commision number |
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