Structure of PDB 4v6x Chain Ca Binding Site BS01 |
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| >4v6x Chain A5 (length=4298)
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cgcgaccucagaucagacguggcgacccgcugaauuuaagcauauuaguc
agcggaggagaagaaacuaaccaggauucccucaguaacggcgagugaac
agggaagagcccagcgccgaauccccgccccgcggcggggcgcgggacau
guggcguacggaagacccgcuccccggcgccgcucguggggggcccaagu
ccuucugaucgaggcccagcccguggacggugugaggccgguagcggccc
ccggcgcgccgggcccgggucuucccggagucggguugcuugggaaugca
gcccaaagcgggugguaaacuccaucuaaggcuaaauaccggcacgagac
cgauagucaacaaguaccguaagggaaaguugaaaagaacuuugaagaga
gaguucaagagggcgugaaaccguuaagagguaaacgggugggguccgcg
caguccgcccggaggauucaacccggcggcggguccggccgugucggcgg
cccggcggaucuuucccgccccccguuccucccgaccccuccacccgccc
ucccuucccccgccgccccgggcuccggcgggugcgggggugggcgggcg
gggccggggguggggucggcgggggaccgucccccgaccggcgaccggcc
gccgccgggcgcauuuccaccgcggcggugcgccgcgaccggcuccggga
cggcugggaaggcccggcggggaagguggcucggggggccccguccgucc
guccggcggcggcggcggcggcgggaccgaaaccccccccgaguguuaca
gcccccccggcagcagcacucgccgaaucccggggccgagggagcgagac
ccgucgccgcgcucuccccccucccggcgcccacccccgcggggacuccc
ccgcgggggcgcgccggcgucuccucgugggggggccgggccaccccucc
cacggcgcgaccgcucucccaccccuccuccccgcgcccccggggugccg
cgcgcgggucggggggcggggcggacuguccccagugcgccccgggcggg
ucgcgccgucgggcccgggggagguucucucggggccacgcgcgcguccc
ccgaagagggggacggcggagcgagcgcacggggucggcggcgacgucgg
cuacccacccgacccgucuugaaacacggaccaaggagucuaacacgugc
gcgagucgggggcucgcacgaaagccgccguggcgcaaugaaggugaagg
ccggcgcgcucgccggccgaggugggaucccgaggccucuccaguccgcc
gagggcgcaccaccggcccgucucgcccgccgcgccggggagguggagca
cgagcgcacguguuaggacccgaaagauggugaacuaugccugggcaggg
cgaagccagaggaaacucugguggagguccguagcgguccugacgugcaa
aucggucguccgaccuggguauaggggcgaaagacuaaucgaaccaucua
guagcugguucccuccgaaguuucccucaggauagcuggcgcucucgcag
acccgacgcacccccgccacgcaguuuuauccgguaaagcgaaugauuag
aggucuuggggccgaaacgaucucaaccuauucucaaacuuuaaaugggu
aagaagcccggcucgcuggcguggagccgggcguggaaugcgagugccua
gugggccacuuuugguaagcagaacuggcgcugcgggaugaaccgaacgc
cggguuaaggcgcccgaugccgacgcucaucagaccccagaaaagguguu
gguugauauagacagcaggacgguggccauggaagucggaauccgcuaag
gaguguguaacaacucaccugccgaaucaacuagcccugaaaauggaugg
cgcuggagcgucgggcccauacccggccgucgccggcagucgagagugga
cgggagcggcgggggcggcgcgcgcgcgcgcgcguguggugugcgucgga
gggcggccuccucccgcccacgccccgcuccccgcccccggagccccgcg
gacgcuacgccgcgacgaguaggagggccgcugcggugagccuugaagcc
uagggcgcgggcccggguggagccgccgcaggugcagaucuuggugguag
uagcaaauauucaaacgagaacuuugaaggccgaaguggagaaggguucc
augugaacagcaguugaacaugggucagucgguccugagagaugggcgag
cgccguuccgaagggacgggcgauggccuccguugcccucggccgaucga
aagggagucggguucagauccccgaauccggaguggcggagaugggcgcc
gcgaggcguccagugcgguaacgcgaccgaucccggagaagccggcggga
gccccggggagaguucucuuuucuuugugaagggcagggcgcccuggaau
ggguucgccccgagagaggggcccgugccuuggaaagcgucgcgguuccg
gcggcguccggugagcucucgcuggcccuugaaaauccgggggagagggu
guaaaucucgcgccgggccguacccauauccgcagcaggucuccaaggug
aacagccucuggcauguuggaacaauguagguaagggaagucggcaagcc
ggauccguaacuucgggauaaggauuggcucuaagggcugggucggucgg
gcuggggcgcgaagcggggcugggcgcgcgccgcggcuggaucuggacgc
gagccgggcccuucccguggaucgccccagcugcggcgggcgucgcggcc
gcgcgguuccgcgcggcgccucgccucggccggcgccuagcagccgacuu
agaacuggugcggaccaggggaauccgacuguuuaauuaaaacaaagcau
cgcgaaggcccgcggcggguguugacgcgaugugauuucugcccagugcu
cugaaugucaaagugaagaaauucaaugaagcgcggguaaacggcgggag
uaacuaugacucucuuaagguagccaaaugccucgucaucuaauuaguga
cgcgcaugaauggaugaacgagauucccacugucccuaccuacuauccag
cgaaaccacagccaagggaacgggcuuggcggaaucagcggggaaagaag
acccuguugagcuugacucuagucuggcacggugaagagacaugagaggu
guagaauaagugggaggcccccggcgcccccccgguguccccgcgagggg
cccggggcgggguccgccggcccugcgggccgccggugaaauaccacuac
ucugaucguuuuuucacugacccggugaggcgggggggcgagccccgagg
ggcucucgcuucuggcgccaagcgcccggccgcgcgccggccgggcgcga
cccgcuccggggacagugccagguggggaguuugacuggggcgguacacc
ugucaaacgguaacgcagguguccuaaggcgagcucagggaggacagaaa
ccucccguggagcagaagggcaaaagcucgcuugaucuugauuuucagua
cgaauacagaccgugaaagcggggccucacgauccuucugaccuuuuggg
uuuuaagcaggaggugucagaaaaguuaccacagggauaacuggcuugug
gcggccaagcguucauagcgacgucgcuuuuugauccuucgaugucggcu
cuuccuaucauugugaagcagaauucaccaagcguuggauuguucaccca
cuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuu
uacccuacugaugauguguuguugccaugguaauccugcucaguacgaga
ggaaccgcagguucagacauuugguguaugugcuuggcugaggagccaau
ggggcgaagcuaccaucugugggauuaugacugaacgccucuaagucaga
aucccgcccaggcggaacgauacggcagcgccgcggagccucgguuggcc
ucggauagccggucccccgccuguccccgccggcgggccgcccccccccu
ccacgggagggcgcgugccccgccgcgcgccgggaccgggguccggugcg
gagugcccuucguccugggaaacggggcgcggccggagaggcggccgccc
ccucgcccgucacgcaccgcacguucguggggaaccuggcgcuaaaccau
ucguagacgaccugcuucugggucgggguuucguacguagcagagcagcu
cccucgcugcgaucuauugaaagucagcccucgacacaaggguuuguc |
.........................<<<<<<.....<......>......
>>>>>.>...{.....<<....>>..<<<<<<.....<<.....>>....
>>>>>>..[[[....<<<...<<<<<<<<<<<...>>>>>>>.>>>>...
..>>>....<<<<<<<<<<...<<<<<<<<.<<<....<<<<<<<<....
<<<<......>>>>.....((......<<<.....))>>>...>.>>>>>
>>>>>>>>>>>>>..>>>>>>>>>>.......<<<<<<<........>>>
>>>>.....(((((..<<<<<<)))))..]]]....}.............
................<<....>>...............<<<<....>>>
>..................................<<<<<<<<..<<<.<
....<<<<<<<<.<<<.....<<<<<<<<<<<...<<<....<<<<<.<.
....<<<<.<<<..<<<<<<<<<<<....<<<<<.<<<<....<<<<<<<
.<<<<<<.<<<<<<<.<<<>>>...>>>>>>>.>.>>>>>.>>>>>>>.>
>>>.>>>>>.>>>>>..>>>>>>>>>>>>>.>>>.>>>......>>>.>>
>>>>>>>>>......>>>.>>>.>>>>>..<<<<<<<<.<<<<<<<<<..
<<<<..........<<<.<<<<...<<.<<<<<<<<.<<<<<<.<<<.<<
<.<<<.>>>>>>>>>>>>.>>>..............>>>>>>>>>.>...
.>>>>.>>>............>>>>....>>>>>>>>>............
.....<..<<<<...<<<<<<<..<<<<<<...<<<<<<<<<<<....>>
>>>>>>>>>.>>>>>><........>..>>>>>>>...<<<<.<<<<..<
<<<<<<<<<<<<<<<...<<.<<<...<<<..<<<<<<<<<>>>>.>>.>
>>...>>>..>>>>>.<<<<<<<.<<<<....>>>>.>>>>>>>>>>.>>
>>>>>>>>>.>>....>.>>>.<<....>>...>>>>.......<<<<<<
<<.....>>>>>>>>.........>>>>.>....>>>.>>>>>...>>>>
...>>>>>>>>..<<<<........>>>><<<<<<...<<<<<<<<<<<<
<<..<<<...<<<<........>>>>.....>>>...<<....>>...<<
<<<<<<....>>>>>>>>..<<<<<...<<<..<<<...(((..[..>>>
..>>>....>>>>>.<<<<<<<<<.<<<<......>>>>>>>>>>>.>>.
...>>>>>>>>>>>>>>.<<.<..<<<<<<<.....<<<<<<<<<..<<<
....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<<.......
.>>>>.>>>....>>>>>>>>>...<<.......>>......>>>>>>..
.>..>.>>..<<<<<<....<.<<<....>>>.><<.<<<<<<<......
.....................<<.<<<<<<<<<...<<<....<<<....
<<<...<<<<<.<.....>.>>>>>.>>>....>>>..>>.>...>>>>>
>>...<<<<<<<<<.........>>>>>>>>>...>>.>>.>>>>>>>..
>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>>...<<
<<<<<...<<<(((.......<<<<<.....<<..........<<<.<<<
<<<<<<<.......<<<<<.<<....<<.........>>....>>.....
....<<......>>...>>>>>...>>>>>>>>>>>>>..........))
).>>...>>>>>..>>>...>>>>>>><<<<<<.<<<...........].
.))).......................<<<.<.<<<.<<<<<<.<<.<<<
<<..<<>>.>>>>>.>>.>>>>>>.>>>..>.>>>...............
........>>>>>>>>>....>>>>>>...<<<<<<<<.<<......<<<
<.<<<<....>>>>>>>>...>>>>>>>>>>........>>>>>><<...
..<<.....<<<<<<.......>>>>>>.<<<.....<<<<<.<<...<<
<<<<...<<.....>>.>>>>>>....(.<<<<<<...<<....<<<...
.>>>..........<<.<<<<<<<<<...>>>>>>>>>>>......>>..
..>>...<<<<<........>>>>>.)<<<<....<<<<...<<<<<<<<
....>>>>>>>>..<<<....>>>...<..<<<<<<<...<<<<<<<<<<
<<.<<<<<<<<<<..{{{..>>>>>>.....<<<<.<<<<.<<<<.....
<<<.....>>>.....>>>>>>>>..>>>>......<<<<<<<.......
>>>>>>>>>>>...>>>>>>>>>>>>.........>>>>>>>..>.....
.....>..>>>.>>>>>>>>..>>.....<<......>>>>>>>.<<<<.
....>>>>..>>>....<<<<.....<<<<<<<.<<..............
.<<<<<...............>>>>><<.<<<<<<<<<<<...<<<<<<.
..<<<<<<<....<<<<<<..<<<<.<<.<<<<<<.<<<<<>>>>>.>>>
>.>>>>.>>>>.>>>>>>....>>>>>>>.....<<<<<<<<<<<<<.<<
<<>>>>.....>>>>>>>>>.>>>>.>>>>>>........>>>>>..>>>
>>>.>>............<<<<<<<<<..<<<.........>>>..<<<<
<<<....<<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<
<.<...<<.....<<<<....>>>>.....>>.>>>>>..>>>>><<<<<
<.......>>>>>>........<...........<<<<<.......>>>>
>.....>.....>>....>>.>>>>>>>.....>>.>>>>>>>..>>>>>
>....>>....<<<<<........>>>>>....[[[[[..{{{.{{....
..[[[[.{{[[[[..<<<<<.<<<<<<<<<.<<<<<<<<<<<<.<<<<..
........<<<<<...<<<<...<<.<<.<<<<<<...<<<<....>>>>
.>>>>>>.>>.<<<....>>>...>>>>>>.............>>>>>.>
>>>.>>.>>>>>>>>>>...<<<<<.....<<<<...<.<<<<<<....>
>>>>>>...............<<<<<<<<<<<.....>>>>>>>>>>>..
>>>>..>>>>>....>>>>>>>>>..>>>>>...<<<.....>>>..<<<
<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......
>>>>>>.....<<.[.(((>>....>>>>>>>...<<<.<<<<<......
.>>>>.>>>>.<<<....>>>.>>)))]......((((((..(((..>>>
>>>.)))))))))..........]]]]..}}]]]].......<<.<...<
<<<<<...<<.......>>...>>>>>>....>.>.>.......<<<<<.
<<<<<<..<.<.<<<<<......>>>>>...>.>.<<<.........>>>
.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}
}..}}}.]]]]].....<<<<<<.<..<<<..<.<<<<<...........
......>>>>>.><<<<....<<<<....<<.<<<<<<.}}}..>>>>..
>>.>>...>>>>...>>>><<<<<...<<<<<...........>>>>>..
.>>>>>.>>>...>.>>>>>>.....<<<<<<<.<<..<<<.....<...
.......<<<<<..<<<<<...<<<<<<<<<<<<<<<<<<<...<<..<<
<<.<>>>>>>>.>>>.>.>>>>>>>.>>>..>>>>>>>>>>.>>>>>...
.....>.........<<<<....<<<<.<<<<<<<......>>>>>>>>>
>>...>>>>....................>>>..>>>>>>>>><<<<<.<
.............>....<<.<<<<<<<.<<.....<<<<....<<<<<.
.....>>>>>...>>>>....>>....>>>>.>>>.>>..>>>>>... |
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| PDB | 4v6x Structures of the human and Drosophila 80S ribosome. |
| Resolution | 5.0 Å |
Binding residue
(original residue number in PDB) | P2 S3 R4 L5 R6 K7 T8 R9 K10 R12 G13 H14 V15 S16 H17 G18 H19 G20 R21 I22 G23 H25 R26 K27 H28 P29 G30 R32 N34 H39 H40 H41 R42 I43 G54 K55 V56 G57 M58 K59 H60 Y61 H62 L63 R65 N74 L81 S83 T86 K110 L112 K114 K116 S130 R131 R132 |
Binding residue
(residue number reindexed from 1) | P1 S2 R3 L4 R5 K6 T7 R8 K9 R11 G12 H13 V14 S15 H16 G17 H18 G19 R20 I21 G22 H24 R25 K26 H27 P28 G29 R31 N33 H38 H39 H40 R41 I42 G53 K54 V55 G56 M57 K58 H59 Y60 H61 L62 R64 N73 L80 S82 T85 K109 L111 K113 K115 S129 R130 R131 |
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| Enzyme Commision number |
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