Structure of PDB 4v6x Chain CR Binding Site BS01

Receptor Information
>4v6x Chain CR (length=189) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSMLRLQKRLASSVLRCGKKKVWLDPNETNEIANANSRQQIRKLIKDGLI
IRKPVTVHSRARCRKNTLARRKGRHMGIGKRKGTANARMPEKVTWMRRMR
ILRRLLRRYRESKKIDRHMYHSLYLKVKGNVFKNKRILMEHIHKLKADKA
RKKLLADQAEARRSKTKEARKRREERLQAKKEEIIKTLS
Ligand information
>4v6x Chain B2 (length=1861) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
cuccggccccggccggggggcgggcgccggcggcuuuggugacucuagau
aaccucgggccgaucgcacgccccccguggcggcgacgacccauucgaac
gucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacc
acgggugacggggaaucaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccga
cccggggagguagugacgaaaaauaacaauacaggacucuuucgaggccc
uguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcgggcg
ggcgguccgcgagccaccgcccguccccgccccuugccucucggcgcccc
cucgaugcucuuagcugagugucccgcggggcccgaagcguuuacuuuga
aaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcua
ggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaacuga
ggccaugauuaagagggacggccgggggcauucguauugcgccgcuagag
gugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugcca
agaauguuuucauuaaucaagaacgaaagucggagguucgaagacgauca
gauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcggcgg
cguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugg
guuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacggga
aaccucacccggcccggacacggacaggauugacagauugauagcucuuu
cucgauuccgugggugguggugcauggccguucuuaguugguggagcgau
uugucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguu
acgcgacccccgagcggucggcgucccccaacuucuuagagggacaagug
gcguucagccacccgagauugagcaauaacaggucugugaugcccuuaga
uguccggggcugcacgcgcgcuacacugacuggcucagcgugugccuacc
cuacgccggcaggcgcggguaacccguugaaccccauucgugauggggau
cggggauugcaauuauuccccaugaacgaggaauucccaguaagugcggg
ucauaagcuugcguugauuaagucccugcccuuuguacacaccgcccguc
gcuacuaccgauuggaugguuuagugaggcccucggaucggccccgccgg
ggucggcccacggcccuggcggagcgcugagaagacggucgaacuugacu
aucuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgg
aaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>.........<<<<...<<<<<<...
.>>>>>>...>>>>[[..(((((.....<<<<<<<<<<<<.<..<<<<<<
<<<<<<<....>>>>>>>>>.>>>>....>>>>..............)))
))......]]...<<<<.<<<<......>>>>>>>>....]]]...}}..
..]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.........
.>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<..
...>>>..>>>......}}.......<<<<<<<<<.<<<....>>>.>.>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..)))))).
]]]............{{.......{{...[[[.[[....<<<.<.<<<<<
<<<<<<.<<>>....>>>>>>>>>>>.>.>>>...<<...<<<..<<<<<
...<<<<<<<......>>>>>>>....>>>>>.>>>.>>..<<<<<..<.
......<<...<.......>.<<<<.......>>>>...>>......>..
>>..>>>.......[[....(((((((.....>>>>>>>>>.))))))).
..]]....]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
.>..>>>.>>>...]]]...}}......<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<
.<<<<......>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>
>>.....<<<......<<<......>>>....>>>..]]]]..<<<<<.<
<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<......<<<<<<.......<<.<<<........>>>.>
>.....>>>>>>.<.<<.<<<..<<<<<<<<<....<<<.<<<<<....>
>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<
....<<<..<<<<....>>>>.>>>....>>>>..>>>>..>.....<<<
<<.....>>>>>........>>>....>>>.>>>...>.>>>>>>>>...
...>>>>>...>>.>>>>.>>>.....<<.<<<........<.......<
<<.<<<<....>>>>.>>>....>.........>>>.>>...........
.<<<<<..........>>>>>...........>>>>>.....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<
<<<<<.....>>>>>>>>>>>>...>>>>>...>>.>>>>..>>>.>>>>
>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>
>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6x Structures of the human and Drosophila 80S ribosome.
Resolution5.0 Å
Binding residue
(original residue number in PDB)		R163 R170 R172 R173
Binding residue
(residue number reindexed from 1)		R163 R170 R172 R173
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0016020 membrane
GO:0022625 cytosolic large ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0045202 synapse
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6x, PDBe:4v6x, PDBj:4v6x
PDBsum4v6x
PubMed23636399
UniProtP84098|RL19_HUMAN Large ribosomal subunit protein eL19 (Gene Name=RPL19)

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