Structure of PDB 4kbb Chain B Binding Site BS01

Receptor Information
>4kbb Chain B (length=417) Species: 1491 (Clostridium botulinum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NNIILNLRYKDNNLIDLSGYGAKVEVYDGVELNDKNQFKLTSSANSKIRV
TQNQNIIFNSVFLDFSVSFWIRIPKYKNDGIQNYIHNEYTIINCMKNNSG
WKISIRGNRIIWTLIDINGKTKSVFFEYNIREDISEYINRWFFVTITNNL
NNAKIYINGKLESNTDIKDIREVIANGEIIFKLDGDIDRTQFIWMKYFSI
FNTELSQSNIEERYKIQSYSEYLKDFWGNPLMYNKEYYMFNAGNKNSYIK
LKKDSPVGEILTRSKYNQNSKYINYRDLYIGEKFIIRRKDIVRKEDYIYL
DFFNLNQEWRVYTYKYFKKEEEKLFLAPISDSDEFYNTIQIKEYDEQPTY
SCQLLFKKDEESTDEIGLIGIHRFYESEYKDYFCISKWYLKEVKRKPYNL
KLGCNWQFIPKDEGWTE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kbb Structure of dual receptor binding to botulinum neurotoxin B.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D1115 S1116 P1117 V1118 Y1181 Y1183 E1191 K1192 F1194 P1197 S1199 E1203 F1204
Binding residue
(residue number reindexed from 1)		D254 S255 P256 V257 Y312 Y314 E322 K323 F325 P328 S330 E334 F335
Enzymatic activity
Catalytic site (original residue number in PDB) Q898 R967
Catalytic site (residue number reindexed from 1) Q37 R106
Enzyme Commision number 3.4.24.69: bontoxilysin.
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:4kbb, PDBe:4kbb, PDBj:4kbb
PDBsum4kbb
PubMed23807078
UniProtP10844|BXB_CLOBO Botulinum neurotoxin type B (Gene Name=botB)

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