Structure of PDB 4aqu Chain B Binding Site BS01

Receptor Information
>4aqu Chain B (length=152) Species: 3055 (Chlamydomonas reinhardtii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTKYNKEFLLYLAGFVDGDGSIIAQIKPNQSYKFKHQLSLTFQVTQKTQR
RWFLDKLVDEIGVGYVRDRGSVSDYILSEIKPLHNFLTQLQPFLKLKQKQ
ANLVLKIIEQLPSAKESPDKFLEVCTWVDQIAALNDSKTRKTTSETVRAV
LD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4aqu 5'-Cytosine-Phosphoguanine (Cpg) Methylation Impacts the Activity of Natural and Engineered Meganucleases.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D220 G221 S222 Q226 K228 Q244 T246 Q247 K248 R270 N336 D337 S338 R341 K342 T343
Binding residue
(residue number reindexed from 1)		D19 G20 S21 Q25 K27 Q43 T45 Q46 K47 R69 N135 D136 S137 R140 K141 T142
Binding affinityPDBbind-CN: Kd=40.8nM
Enzymatic activity
Catalytic site (original residue number in PDB) G219 D220
Catalytic site (residue number reindexed from 1) G18 D19
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006314 intron homing
Cellular Component
GO:0009507 chloroplast

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4aqu, PDBe:4aqu, PDBj:4aqu
PDBsum4aqu
PubMed22740697
UniProtP05725|DNE1_CHLRE DNA endonuclease I-CreI

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