Structure of PDB 7pzy Chain AB Binding Site BS01 |
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| >7pzy Chain 1 (length=3209)
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ugaccucaaaucagguaggacuacccgcugaacuuaagcauaucaauaag
cggaggaaaagaaaccaacagggauugccucaguagcggcgagugaagcg
gcaaaagcucaaauuugaaaucuggcgucuuuggcguccgaguuguaauu
ugaagaagguaucuuugggcccggcucuugucuauguuccuuggaacagg
acgucacagagggugagaaucccgugcgaugagaugacccgggucugugu
aaaguuccuucgacgagucgaguuguuugggaaugcagcucuaagugggu
gguaaauuccaucuaaagcuaaauauuggcgagagaccgauagcgaacaa
guacagugauggaaagaugaaaagaacuuugaaaagagagugaaaaagua
cgugaaauuguugaaagggaagggcuugagaucagacuugguauuuugca
ugcugcgguuuaccgggccagcaucgguuuggagcggcaggauaauggcg
gaggaauguggcacggcuucugcuguguguuauagccucugacgauacug
ccagccuagaccgaggacugcgguuuuuaccuaggauguuggcauaauga
ucuuaagucgcccgucuugaaacacggaccaaggagucuaacgucuaugc
gaguguuuggguguaaaacccguacgcguaaugaaagugaacgaaggugg
gggcccauuagggugcaccaucgaccgauccugauguguucggauggauu
ugaguaagagcauagcuguugggacccgaaagauggugaacuaugccuga
auagggugaagccagaggaaacucugguggaggcucguagcgguucugac
gugcaaaucgaucgucgaauuuggguauaggggcgaaagacuaaucgaac
caucuaguagcugguuccugccgaaguuucccucaggauagcagaagcuc
guaucaguuuuaugagguaaagcgaaugauuagaagucuugggguugaaa
ugaccuuaacuuauucucaaacuuuaaauauguaagaaguccuuguugcu
uaauugaacguggacaauugaaugaagagcuuuuagugggccauuuuugg
uaagcagaacuggcgaugcgggaugaaccgaacgugaaguuaaagugccg
gaaugcacgcucaucagacaccacaaaagguguuaguucaucuagacagc
cggacgguggccauggaagucggaauccgcuaaggaguguguaacaacuc
accggccgaaugaacuagcccugaaaauggauggcgcucaagcgugcuac
uuauacuucaccgugauugcuguuuugacgcuuucacgaguaggcaggcg
uggaggucagugacgaagccuuugcuguaaagcugggucgaacggccucu
agugcagaucuuggugguaguagcaaauauucaaaugagaacuuugaaga
cugaaguggggaaagguuccaugucaacagcaguuggacauggguuaguc
gauccuaagagauggggaagcuccguuucaacgugcuugauuuuucaggc
caaccaucgaaagggaauccgguuaaaauuccggaacuuggauauggauu
cuucacggcaacguaacugaauguggagacgucggcgugagcccugggag
gaguuaucuuuucuucuuaacagcuuaucacccuggaauugguuuauccg
gagauggggucuuauggcuggaagagcgcgguaauuuugccgcguccggu
gcgcuuacgacgguccuugaaaauccacaggaaggaauaguuuucaugcc
aagucguacucauaaccgcagcaggucuccaagguuaacagccucuaguu
gauagaauaauguagauaagggaagucggcaaaauagauccguaacuucg
ggauaaggauuggcucuaaggaucgggugucuugggccuuguguagacgc
gaggucuuuauggccguccggggcacguuuaacgaucaacuuagaacugg
uacggacaaggggaaucugacugucuaauuaaaacauagcauugugaugg
ucagaaagugauguugacacaaugugauuucugcccagugcucugaaugu
caaagugaagaaauucaaccaagcgcggguaaacggcgggaguaacuaug
acucucuuaagguagccaaaugccucgucaucuaauuagugacgcgcaug
aauggauuaacgagauucccacugucccuaucuacuaucuagcgaaacca
cagccaagggaacgggcuuggcagaaucagcggggaaagaagacccuguu
gagcuugacucuaguuugacauugugaaaaguuuuuacuuauucaaugaa
gcggagcuggaggucaaacuccacguucuagcauuaagcccucugggcga
uccggguugaagacauugucagguggggaguuuggcuggggcggcacauc
uguuaaacgauaacgcagguguccuaagggggacucauggagaacagaaa
ucuccaguagaacaaaaggguaaaaguccccuugauuuugauuuucagug
ugaauacaaaccaugaaaguguggccuaucgauccuuuagucccucggaa
uuugaggcuagaggugccagaaaaguuaccacagggauaacuggcuugug
gcagucaagcguucauagcgacauugcuuuuugauucuucgaugucggcu
cuuccuaucauaccgaagcagaauucgguaagcguuggauuguucaccca
cuaauagggaacgugagcuggguuuagaccgucgugagacagguuaguuu
uacccuacugaugaauguuaucgcaauaguaauugaacuuaguacgagag
gaaccguucauucagauaauugguuuuugcggcugucugaucaggcaacg
ccgcgaagcuaccaucugcuggauuauggcugaacgccucuaagucagaa
uccaugcuagaacgcgaugauuuuugcccugcacauuuuagauggauacg
aauaagacuuuuuagucgcuggaccauagcaggcuggcaacggugcgcuu
agcggaaaggcuuugugcgcuugccggcggauagcaaugucaacaugcgc
ggggauaaauccuuugcauacgacuuagauguacaacggaguauuguaag
caguagaguagccuuguuguuacgaucugcugagauuaagcucuuguugu
cugauuugu |
.......................<<<<<<.....<......>......>>
>>>.>.........<<....>>..<<<<<......<<.....>>.....>
>>>>..[[[...<.......<<.<<<<<<...>>>>>>.>>.......>.
....<<<<<...<<<<<<<<<<<<.<<<<<<<<....<<<<......>>>
>.(.......<<<......)>>>..>.>>>>>>>....>>>>>>>>....
>>>>..>>>>>........<<<<<<<........>>>>>>>.....((((
(..<<<<<<)))))..]]]...............................
...<<....>>...............<<<<....>>>>............
......................<<<<<<<<<<<<.....<<<......<.
....>......>>>..<<<<<<<.<<<<<<<<.<<<<<<<....<<.<<<
<<<<......<<<<<<......>>>>>>.......>>>>>>.>.>>.>>>
>>.>>>>>>>>>>........<<<....>>>.....>>>>>>>....>>>
>>>>>>>>>..<<<<........>>>><<<<<<....<<<<<<.<<<<<<
..<<<..<<<<<.....>>>>>..>>>...<<....>>.......<<<<<
..<<<<....>>>>...>>>>>.<<<<<<<<...<<....>>...>>>.>
>>.>>....>>>>>>.>>>>>>..<<.<..<<<<<<<.....<<<<<<<<
<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<<.<<.<<.
.......>>>>>>>>....>>>>>>>>>...<<.......>>......>>
>>>>...>..>.>>..<<<<<<....<.<<<....>>>.><<<<<<<<<<
...<<<.<<<<<<<.....<<<....<<<....<<<<...<<<<<<....
.>>>>>>.>>>>....>>>..>.>>.....>>>>>...<<<<.<<<<.<.
.....>>>>>.>>>>.....>>>>>.>>>>>>>>.>>..<<<<.<<<<<.
....>>>>>.>>>>....<<<......>>>...<<<<<<<..<<<<(((.
....<<<<<<.....<<..........<<<.<<<<<<<<<<.......<<
<<<.<<....<<.........>>....>>.........<<......>>..
.>>>>>...>>>>>>>>>>>>>..........))).>>...>>>>>>.>>
>>..>>>>>>><<<<<..<<.........>>..>>>>>....>>>>>>..
<<<<<<<<.<<......<<<<..<<<....>>>.>>>>...>>>>>>>>>
>........>>>>>><<.....<<.....<<<<<<.......>>>>>><<
<<.....<<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<
<<<<<...<<....<<<....>>>..........<<<<<<....>>>>>>
......>>....>>...<<<<<........>>>>>))<<<<.<<<<<<<.
....<<<....>>>.......<<<<<<...<<<<.<<<<<<<.<<<<<<<
<<<..{{{..>>>>>><...<<<<<....<<<<<<....<<<.....>>>
....>>>>>>.....>>>>>....><<<<<<<......>>>>>>>>>>>.
..>>>>>>>.>>>>.........>>>>>>..........>>>..>>>>>>
>>>>>>..>>.....<<......>>>>>>>.<<<<.....>>>>..>>>>
..<<<<.....<<<<<<<.<<.........<.....<<<<<.........
......>>>>><<.<<<<<<<<<<<..<<<<<.<<.....<<<.<<<..<
..>.>>>.>>>......>>>>>.>>.......>>>>>..>>>>>>.>>..
..........<<<<<<<<<..<<<.........>>>..<<<<<<<....<
<<<.....>>>>......>>>>>>>...<<..<<<..<<<<<<....<<<
.....<<<<....>>>>.....>>>.>>>>..>>>>><<<<<<.......
>>>>>>........<...........<<<<<.......>>>>>.....>.
....>>....>>.>>>>>>>..>..>>.>>>>>>>..>>>>>>....>>.
...<<<<<........>>>>>....[[[[[..{{{.{{......[[[[.{
{[[[[..<<<<<.<<<<<<<<..<<<<<<<.>>>>>>>...<<<<<....
.<<<<..<<<<<......>>>>>..............<<<<...>>>>..
>>>>..>>>>>.....>>>>>>>>..>>>>>...<<<.....>>>..<<<
<<<...........>>>>>>..<<...<<<<<<<...<<<<<<.......
>>>>>>.....<<...(((>>....>>>>>>>...<<<.<<<<<......
.>>>>.>>>>.<<<....>>>.>>))).......((((((..((((.>>>
>>>))))))))))..........]]]]..}}]]]].......<<.<.<.<
<<<<<...<<.......>>...>>>>>>...>>.>.>.......<<<<<.
<<<<<<..<.<<<<<<<......>>>>>>>...>.<<<.........>>>
.....>>>>>..>...>>>.>>....<<<<<<<....>>>.>>>>....}
}..}}}.]]]]]....<<<<<<<<..<<<<.<.<<<<<............
.....>>>>>.><<<<<...<<<<....<<<<<<<<<<}}}.>>>>>..>
>>>>...>>>>..>>>>>.<<<<...<<<<<...........>>>>>...
>>>>.>>>>....>>>>>>>>.....<<<<<<.<<<.......<<.....
.....<<<<....>>>>......>>.......<<<<<<...<<<<<<<..
<<<......>>>..>>>>>>>.>>>>>>................>>>.>>
>>>>..<<<<<<<.............>>....<<<<<<<<<.<<<....<
<<<....<<<<<......>>>>>...>>>>...>>>....>>>>.>>>>>
..>>>>>.. |
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| PDB | 7pzy E-site drug specificity of the human pathogen Candida albicans ribosome. |
| Resolution | 2.32 Å |
Binding residue
(original residue number in PDB) | P2 T3 R4 T6 K7 T8 R9 K10 H11 R12 G13 N14 V15 A17 G18 K19 G20 R21 I22 G23 K24 H25 R26 K27 H28 P29 G30 G31 R32 G33 K34 G36 H39 H40 H41 R42 T43 N44 K47 Y52 F53 G54 K55 V56 G57 M58 R59 Y60 F61 H62 K63 Q64 N66 H67 R70 E72 N74 K111 L113 G114 K115 R117 S131 K132 L133 |
Binding residue
(residue number reindexed from 1) | P1 T2 R3 T5 K6 T7 R8 K9 H10 R11 G12 N13 V14 A16 G17 K18 G19 R20 I21 G22 K23 H24 R25 K26 H27 P28 G29 G30 R31 G32 K33 G35 H38 H39 H40 R41 T42 N43 K46 Y51 F52 G53 K54 V55 G56 M57 R58 Y59 F60 H61 K62 Q63 N65 H66 R69 E71 N73 K110 L112 G113 K114 R116 S130 K131 L132 |
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| Enzyme Commision number |
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