Structure of PDB 8sj7 Chain A Binding Site BS01

Receptor Information
>8sj7 Chain A (length=404) Species: 6239 (Caenorhabditis elegans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPTWSLMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLTSYQKFQ
LFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQEKLKNF
ISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLIAICVDQ
NANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVVQTIIEK
LTADSMNVDLTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIV
SNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMM
DEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKE
GGYDHAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLANLRSTHSLM
LEPR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8sj7 Competing intrinsically-disordered regions and electrostatic repulsion regulate PUF RNA-binding affinity
Resolution2.09 Å
Binding residue
(original residue number in PDB)		N244 Y245 F285 R288 Q291 Q322 N323 H326 Q329 Y361 R364 Q367 Y413 N415 Y416 Q419 K450 S453 H454 E457 F495 N500 Y501 Q504 F552 S553 S554 K557
Binding residue
(residue number reindexed from 1)		N72 Y73 F113 R116 Q119 Q150 N151 H154 Q157 Y189 R192 Q195 Y241 N243 Y244 Q247 K278 S281 H282 E285 F323 N328 Y329 Q332 F380 S381 S382 K385
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:8sj7, PDBe:8sj7, PDBj:8sj7
PDBsum8sj7
PubMed37953271
UniProtQ09312|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)

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