Structure of PDB 8k23 Chain A Binding Site BS01

Receptor Information

>8k23 Chain A (length=929) Species: 979527 (Vibrio phage ICP1_2004_A)

MFIRIKCFSKQPIAKKVSREVSAYLEYTGNNTWEGHISGQGVSNLQTKLI
NVGKGVKVVCNYQDKVLFAIGNVAMSDTGSVPKYTTKKVYKPDDSIFTLK
QGLVGVAALWHDLGKANSYFQRKLRGECNPSDPVRHEWVSGVIVSTFAKG
NDWLSDDFIIPEVKHSDNVFGDDQVLNAVLWLINTHHKKGLVEDPIYRAT
KTMFTETLQCVNVNGGWFNYGDNIDECYKIDTSFITDTYVKQLNRYRKKL
LATKHIWFTLGEDQKIAILQECRVALMLGDSNFSSDLIGGDGSHLYANLD
ECGNLKQTLTQHLLGVTDCALKALFTINHHKPVKANFIPTIAEKGEGKFA
WQNGVNMVDSSIDNMFCINMASTGKGKTLANLKLLQHFGNVRCSFGLGMV
SLTKQTAKQFLDMGVDYNSAAMVTGFSKSRFNLGSESLDQDEVSVEYWGQ
TSSLSKVFPNNNAGFKNKKLLSAPILVTTTDHLVKASGVKKGNKQMLPYV
RCMHSDLVLDEIDDYGIEDMVVLARLVYLTACYGNKVIISSATITPAISN
IFYEAYSSGYKVFCANKQTTYKGVNVVWWDEFGIKVEKVTDQFSNLNTRF
VNKRITNLLESTPKHKALVVDQDDNMEAVKQSITTLHNAHNSGGVSFGLI
RTTTIKDCVAVTQELQNWETDLSIKILCYHSRFVGDTKAQMEEYLSKVLN
RKGDEYKKFVDTTTPTAYIVVATPVVEVGRDFDFDWAIIEPSSERSIVQC
AGRVLRHRSSTPTTHNIHILKYPFKFYRNSNICYDVAGYESKGYKLKSKN
MLDIYKKESIVNSVNRLQGDAAFYTKSLTALEHKVLLDKLTTDIADTNVF
VGGWQLTANPHEYCKWRRGTKNEDLVLTDGKWSGNVTTTKPIQSKIWRKW
QGENGSITVPEYLLDKTICYNDFYGGYEN

Ligand information

>8k23 Chain R (length=31)

ggctttcgtcaaccctttgcttatcttccct

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8k23 ICP1 Csy-dsDNA-Cas1-Cas2/3 complex (fully assembled form) composited structure with C1 symmetry
• Resolution: 3.75 Å
• Binding residue (original residue number in PDB): M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870
• Binding residue (residue number reindexed from 1): M399 V400 T424 G425 T479 D481 H482 T653 T654 I655 K656 S681 T723 P724 V725 V786 A787 R867 T870

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0051607 defense response to virus

External links

• PDB: RCSB:8k23, PDBe:8k23, PDBj:8k23
• PDBsum: 8k23
• UniProt: F1D5V9