Structure of PDB 2pnx Chain A Binding Site BS01

Receptor Information
>2pnx Chain A (length=51) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPTYCLCHQVSYGEMIGCDNPDCSIEWFHFACVGLTTKPRGKWFCPRCSQ
E
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2pnx ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation
Resolution1.8 Å
Binding residue
(original residue number in PDB)
Y198 S205 Y206 G207 E208 M209 I210 G211 C212 D213 W221 F224 P233 G235
Binding residue
(residue number reindexed from 1)
Y4 S11 Y12 G13 E14 M15 I16 G17 C18 D19 W27 F30 P39 G41
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2pnx, PDBe:2pnx, PDBj:2pnx
PDBsum2pnx
PubMed19187765
UniProtQ9UNL4|ING4_HUMAN Inhibitor of growth protein 4 (Gene Name=ING4)

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