Structure of PDB 1a44 Chain A Binding Site BS01

Receptor Information

>1a44 Chain A (length=185) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PVDLSKWSGPLSLQEVDERPQHPLQVKYGGAEVDELGKVLTPTQVKNRPT
SITWDGLDPGKLYTLVLTDPDAPSRKDPKYREWHHFLVVNMKGNNISSGT
VLSDYVGSGPPKGTGLHRYVWLVYEQEGPLKCDEPILSNRSGDHRGKFKV
ASFRKKYELGAPVAGTCYQAEWDDYVPKLYEQLSG

Ligand information

Ligand ID

ACT

InChI

InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/p-1

InChIKey

QTBSBXVTEAMEQO-UHFFFAOYSA-M

SMILES

Software	SMILES
ACDLabs 10.04	[O-]C(=O)C
OpenEye OEToolkits 1.5.0	CC(=O)[O-]
CACTVS 3.341	CC([O-])=O

Formula

C2 H3 O2

Name

ACETATE ION

PDB chain

1a44 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	1a44 Crystal structure of the phosphatidylethanolamine-binding protein from bovine brain: a novel structural class of phospholipid-binding proteins.
Resolution	1.84 Å
Binding residue (original residue number in PDB)	H85 G109
Binding residue (residue number reindexed from 1)	H85 G109
Annotation score	1

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005524	ATP binding
GO:0008289	lipid binding

	Biological Process
GO:0010466	negative regulation of peptidase activity
GO:0043409	negative regulation of MAPK cascade

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1a44, PDBe:1a44, PDBj:1a44
PDBsum	1a44
PubMed	9782057
UniProt	P13696\|PEBP1_BOVIN Phosphatidylethanolamine-binding protein 1 (Gene Name=PEBP1)

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