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rMSA
RNA Multiple Sequence Alignment

rMSA is a composite approach to generate high quality multiple sequence alignment with large alignment depth and diverse sequence sources by merging sequences from NCBI nucleotide (NT) databases and RNAcentral database. Large-scale benchmark data show that rMSA profiles consistently improves RNA secondary structure and contact prediction.


Online server (view example output)

    Cut and paste your sequence (in FASTA format) below: Example input

    Or upload the sequence from your local computer:

    Email: (mandatory, where results will be sent to)

    ID: (optional, your given name of the protein)


References:

  • Chengxin Zhang, Yang Zhang, Anna Marie Pyle rMSA: A Sequence Search and Alignment Algorithm to Improve RNA Structure Modeling. Journal of Molecular Biology, 435: 167904 (2023). (download PDF and Support Information)

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