Zhanglab forum

I utilized TACOS to generate a homodimer of 3CL protease just as a control but when I checked the distance of the active site, it is around 7.6 angstroms compared to the 3.6 angstrom distance of a downloaded crystal structure from RCSB. I am wondering if TACOS is not appropriate for this function and a better method exists.

Dear user,

TACOS is not released online, it is still a beta test version. So please try

https://zhanggroup.org/PEPPI/
https://zhanggroup.org/COTH/
https://zhanggroup.org/SPRING/
https://zhanggroup.org/Threpp/

Those are PPI modeling tools, see if the issue could be addressed.

Thank you.

Best
IT Team