Zhanglab forum

Posted: **Tue Jan 06, 2026 3:42 pm**

Hi,

I am executing DeepFoldRNA on H100 as well as RTX 4080. The program is running for a long time (~ 12 hours) at the stage of LBFGS optimization.

I am running 5kv7A example. How much time ideally complete run should take?

>5v17A
GGAUCAACCCCAGGUGUGGCACACCAGUCAUACCUUGAUCC

Best,
Mandar

Posted: **Thu Jan 08, 2026 12:12 pm**

Quick update: SimRNA and QRNAs executables are working fine. I broke the LBFGS stuck at step 1, and it moved to refining next model, it failed for 4 models and refined 1 model.

What could be the probable issue here?

Posted: **Thu Feb 05, 2026 4:51 pm**

kulkarnim_bii wrote: ↑Tue Jan 06, 2026 3:42 pm Hi, Kart Bros IO

I am executing DeepFoldRNA on H100 as well as RTX 4080. The program is running for a long time (~ 12 hours) at the stage of LBFGS optimization.

I am running 5kv7A example. How much time ideally complete run should take?

>5v17A
GGAUCAACCCCAGGUGUGGCACACCAGUCAUACCUUGAUCC

Best,
Mandar

I am running 5kv7A example. How much time ideally complete run should take?

Zhanglab forum

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