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PPLM-Affinity Results for Example

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   Predicted binding affinity: -7.6090136
Receptor sequences
>4zgq_B (102 amino acids)
LPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLE

Ligand sequences
>4zgq_A (272 amino acids)
TLILTKNQVLHCQFSSWYSLFRKLTPKAKVIKPIPATVLKYLHEDSIYVEQPAYYPEREAIQLIEKAIKELGGAVVPKLNWSTPKDALWITTTGSLKCTTAEEVLLLLKSSDFVAHDLNHAFDDCKDFDNADPKDFSFELVLKEWFPMHASTEFRCFVKSKRLIAFCQRDDNYYEFLKENIDCYEKLISDLLKKLDTFPDPDFVFDVYIHKDRAWLIDINPFYPRTDGLLFSWSELESMNSENMKPEIRLIPKASEGENLLEFAQKWQDLTN

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References

  • Jun Liu, Hungyu Chen, Yang Zhang. A Protein-Protein Language Model for Interaction, Binding Affinity, and Interface Contact Prediction. In preparation.