LOMETS results for example-D2

[Click result.zip to download all results on this page]

Input Sequence in FASTA format

>example-D2 (57 residues)
RIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL

Predicted Secondary Structure

Sequence	20 40 \| \| RIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
Prediction	CCCHHHHHHHHHHCCCCSSSSSCCSSSSSSSSSSSSCCCCCCCHHHHHHHHHHHHHC
Conf.Score	964999999999889968997678899986789866566577789999999999769
	H:Helix; S:Strand; C:Coil

Predicted Solvent Accessibility

Sequence	20 40 \| \| RIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
Prediction	845551153056314404325534103124414135442634232253036126636
	Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Contact and Distance Map Used in LOMETS

Contact Map

Distance Map

LOMETS threading is guided by the consensus contact map (left figure) and distance map (right figure) derived based on confidence scores of DeepPotential. In the contact and distance maps, the axes mark the residue index along the sequence. For the contact map, each dot represents a residue pair with predicted contact, while for the distance map a color scale represents a distance of 1-20+ angstroms. No dot is close to the diagonal in the contact map, because LOMETS does not consider contacts for residue pairs separated by <4 residues.

Top 10 Templates Identified by LOMETS

Rank

PDB
Hit

RCSB
Link

CMO

MAE

ID1

ID2

Cov

Norm.
Zscore

Download
Alignment

                  20                  40

                   |                   |

Sec.Str.
Sol.Acc.
Seq

CCCHHHHHHHHHHCCCCSSSSSCCSSSSSSSSSSSSCCCCCCCHHHHHHHHHHHHHC
845551153056314404325534103124414135442634232253036126636
RIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL

7mj0A

7mj0

0.358

3.823

0.25

1.00

0.35

HHpred

RLSAEKFAALQPALPTAVYHATAQCMTVGEQPAPKTPGVTAGTPVAEEAAVTAETFG

6y2qA1

6y2q

0.540

2.119

0.12

1.00

0.90

Hybrid-CEthreader

NIETESRQFIENKNYSIQSIGPMLRVVFTRLATVDQYLTGANRSLGQELADHLFETI

6y2qA1

6y2q

0.540

2.119

0.12

1.00

0.85

CEthreader

NIETESRQFIENKNYSIQSIGPMLRVVFTRLATVDQYLTGANRSLGQELADHLFETI

5v8wA

5v8w

0.423

2.052

0.21

1.00

0.83

SparksX

IPVEQFVQTLEKHFSDIKVEDTGHIVLLQELIQIEEDSCDNDEMLRVRLRDLVLKFL

6y2qA1

6y2q

0.606

1.899

0.04

0.98

0.97

MapAlign

LVRANIETESRQFIQSIGPMGSRAGLRVVFTVDIFYTTIQYNRSLGQELADHLFET-

7mj0A

7mj0

0.299

4.051

0.23

0.21

0.93

0.60

MRFsearch

---AEKFAALQPALPTAVYHATAQCMTVGGYIAVVTA-GTSDQPVAEEAAVTAETFG

7mj0A

7mj0

0.358

3.823

0.25

1.00

0.34

HHsearch

RLSAEKFAALQPALPTAVYHATAQCMTVGEQPAPKTPGVTAGTPVAEEAAVTAETFG

5v8wA

5v8w

0.416

2.148

0.18

1.00

0.67

MUSTER

SIPEQFVQTLEKHFSDIKVEDTAKGHIVLLETLIQIEECDNDEMLRVRLRDLVLKFL

2hg7A

2hg7

0.255

3.628

0.10

0.09

0.89

0.38

FFAS3D

-----LYDAIMYKYPNAVSRKDFELRNDGNGSYIEKWNLRAPLPTQAELETWWEEL-

7agvA1

7agv

0.423

3.351

0.06

0.05

0.93

0.78

EigenThreader

SGLN--IKENDLGIGKKFIETHEKMTIIIGRREIFNESLDDS--EARQIAAILGPQA

(a)	Templates are ranked in descending order of the following score: score(i,j)=conf(i)·Z(i,j)/Z₀(i)+seqid(i,j), where Z(i,j) is the Z-score of j-th template of i-th server; Z₀(i) is the Z-score cutoff for defining good/bad templates for the i-th server; conf(i) is the confidence of i-th server which is defined as the average TM-score to the natives of all predictions calculated from a large-scale benchmark test; and seqid(i,j) is the sequence identity to query of j-th template of i-th server. (See here for details)
(b)	PDB Hit is the PDB of the specific domain/chain aligned to the query.
(c)	RCSB Link is the RCSB PDB link of the full-length protein.
(d)	CMO is the contact map overlap score, calculated from the number of overlapping contacts between the predicted contact map and the contact map derived from the aligned template, then normalized by the number of predicted contacts.
(e)	MAE is the mean absolute error between the predicted distance map and the distance map derived from the aligned template.
(f)	ID1 is the number of template residues identical to query divided by the number of aligned residues.
(g)	ID2 is the number of template residues identical to query divided by the query sequence length.
(h)	Cov is equal to the number of aligned template residues divided by the query sequence length.
(i)	Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(j)	Download Alignment list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.
(k)	Sec.Str. is predicted secondary structure, with H, S and C representing helix, strand, and coil, respectively.
(l)	Sol.Acc. is predicted solvent accessibility, where values range from 0 (buried residue) to 8 (highly exposed residue)
(m)	Images of the top 10 PDB hits are listed below, together with the threading programs used to detect them:

7mj0
HHpred,MRFsearch,
HHsearch

6y2q
Hybrid-CEthreader,CEthreader,
MapAlign

5v8w
SparksX,MUSTER

2hg7
FFAS3D

7agv
EigenThreader

Full-Length Models

LOMETS uses L-BFGS to construct full-length models guided by the distance restraints predicted by DeepPotential and calculated from top detected templates.
By dragging your mouse on the images, you can rotate and zoom the structure.

Download Model 1
Download Model 2
Download Model 3
Download Model 4
Download Model 5

Proteins with similar structure

LOMETS uses the TM-align structural alignment program to match the first model to all structures in the PDB library.
This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e., the highest TM-score, to the predicted model.
Due to the structural similarity, these proteins often have similar functions to the target.

Top 10 structural analogues in PDB (as identified by TM-align)

Rank	RCSB Link	TM-score	RMSD^a	IDEN^a	Cov.	Download PDB	Download FASTA
1	1m5q	0.78	1.78	1.0	1.0	1m5qY2	1m5qY2
2	1m5q	0.78	1.78	1.0	1.0	1m5qY	1m5qY
3	1k0e	0.722	1.88	0.073	0.96	1k0eA	1k0eA
4	5v8w	0.703	1.9	0.109	0.96	5v8wB	5v8wB
5	5v8w	0.688	2.09	0.214	0.98	5v8wA	5v8wA
6	7lht	0.682	2.12	0.055	0.96	7lhtA2	7lhtA2
7	3osm	0.681	2.29	0.035	1.0	3osmA	3osmA
8	1wqa	0.681	2.28	0.185	0.94	1wqaA	1wqaA
9	1wqa	0.681	2.28	0.185	0.94	1wqaA4	1wqaA4
10	7bfq	0.675	2.05	0.109	0.96	7bfqB	7bfqB

(a)	Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b)	Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c)	RMSD^a is the RMSD between residues that are structurally aligned by TM-align.
(d)	IDEN^a is the percentage sequence identity in the structurally aligned region.
(e)	Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by the length of the query protein.
(f)	Download PDB provides the structure of the aligned model and template.
(g)	Download FASTA provides the fasta format and full-length alignment of model and template. Shows alignment for potential ligand binding pockets and GO/EC terms.

Function and Ligand Binding Annotation for Proteins with Similar Structure

(a)	PDB Hit is the PDB of the specific domain/chain aligned to Model 1
(b)	RCSB Link is the RCSB PDB link of the full-length protein.
(c)	Gene Ontology (GO) term and Enzyme Commission (EC) number list the function annotations for structurally aligned proteins, as collected by BioLiP database.
(d)	Ligand lists known binding ligands for each aligned protein, as collected by BioLiP database.
(e)	Binding Site Residues lists the known binding residues for each ligand as collected by BioLiP database. The residue numbering is based on the specfic domain/chain numbering and highlighted residues means they are present in the alignment with Model 1. Note: Listed binding residues may not be representative of the full ligand binding pocket and may be part of a complex with another protein chain/domain. Also, for a single ligand, one template may have multiple binding sites.

Rank	PDB Hit	RCSB Link	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	1m5qY2	1m5q		GO:0000398	GO:0005732
2	1m5qY	1m5q		GO:0000398	GO:0005732
3	1k0eA	1k0e	GO:0046820,GO:0016740,GO:0000287	GO:0009058,GO:0009396,GO:0046654,GO:0046656		2.6.1.85	TRP	L32 H33 S34 Y41 S42 R43 F44 P238 F239 S240 I378 S390
4	5v8wB	5v8w				3.1.27.-
5	5v8wA	5v8w
6	7lhtA2	7lht
7	3osmA	3osm				2.7.11.1
8	1wqaA	1wqa	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8	MG	S101 D243 D245 D247 R248
9	1wqaA4	1wqa	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8
10	7bfqB	7bfq

Top Templates and Function Annotation from Component Threading Programs

LOMETS combines templates from multiple individual threading programs, as listed in the following tables.

(a)	Templates are ranked in descending order of normalized Z-score, as explained by (i) below.
(b)	PDB Hit is the PDB of the specific domain/chain aligned to the query.
(c)	RCSB Link is the RCSB PDB link of the full-length protein.
(d)	CMO is the contact map overlap score, calculated from the number of overlapping contacts between the predicted contact map and the contact map derived from the aligned template, then normalized by the number of predicted contacts.
(e)	MAE is the mean absolute error between the predicted distance map and the distance map derived from the aligned template.
(f)	ID1 is the number of template residues identical to query divided by the number of aligned residues.
(g)	ID2 is the number of template residues identical to query divided by the query sequence length.
(h)	Cov is equal to the number of aligned template residues divided by the query sequence length.
(i)	Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(j)	Download PDB provides the structure of the aligned region for each template.
(k)	Download FASTA provides the fasta format and full-length alignment of model and template. Shows alignment for potential ligand binding pockets and GO/EC terms.
(l)	Gene Ontology (GO) term and Enzyme Commission (EC) number list the function annotations for template proteins, as collected by BioLiP database.
(m)	Ligand lists known binding ligands for each template protein, as collected by BioLiP database.
(n)	Binding Site Residues lists the known binding residues for each ligand as collected by BioLiP database. The residue numbering is based on the template PDB numbering and highlighted residues means they are aligned with the query sequence. Note: Listed binding residues may not be representative of the full ligand binding pocket and may be part of a complex with another protein chain/domain. Also, for a single ligand, one template may have multiple binding sites.

Templates from Hybrid-CEthreader

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	6y2qA1	6y2q	0.540	2.119	0.12	0.12	1.68	0.90	template_1	template_1
2	7cunI2	7cun	0.504	1.791	0.19	0.19	1.35	0.85	template_2	template_2
3	2f7lA3	2f7l	0.489	2.003	0.21	0.21	1.53	0.82	template_3	template_3	GO:0016868,GO:0000287,GO:0008966,GO:0016853,GO:0046872	GO:0005975,GO:0071704		5.4.2.2,5.4.2.8
4	7bfqB2	7bfq	0.460	2.041	0.07	0.07	1.58	0.72	template_4	template_4
5	1wqaA4	1wqa	0.423	2.395	0.16	0.16	1.53	0.64	template_5	template_5	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8
6	6gykO2	6gyk	0.416	2.641	0.16	0.16	1.42	0.62	template_6	template_6	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0000995,GO:0016251,GO:0001016,GO:0001186,GO:0001179,GO:0001102,GO:0003677,GO:0097718,GO:0005515,GO:0001092,GO:0003682,GO:0008301	GO:0006366,GO:0001188,GO:0006355,GO:0070898,GO:0070893,GO:0042790,GO:0051123	GO:0005667,GO:0005669,GO:0000126,GO:0005634,GO:0005672,GO:0032991,GO:0005654
7	4b0aA1	4b0a	0.416	2.895	0.14	0.14	2.74	0.62	template_7	template_7	GO:0003677	GO:0006352		2.3.1.48	CA CA	G29 D31 D31 D38 Y39 N92
8	1e6yE1	1e6y	0.416	2.680	0.11	0.11	2.54	0.61	template_8	template_8	GO:0050524,GO:0016740	GO:0015948		2.8.4.1
9	3vn5A1	3vn5	0.431	2.283	0.18	0.18	1.18	0.59	template_9	template_9	GO:0004523,GO:0003723,GO:0003676,GO:0004519,GO:0016787,GO:0046872,GO:0004518,GO:0000287	GO:0090305,GO:0090502,GO:0016070,GO:0006298,GO:0043137,GO:0006401	GO:0005737,GO:0032299	3.1.26.4
10	5wq7A5	5wq7	0.394	2.169	0.13	0.11	1.09	0.59	template_10	template_10	GO:0008565	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279

Templates from SparksX

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	5v8wA	5v8w	0.423	2.052	0.21	0.21	1.35	0.83	template_1	template_1
2	5wq8A4	5wq8	0.372	2.177	0.04	0.04	1.11	0.81	template_2	template_2	GO:0008565,GO:0042802	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
3	7cunI2	7cun	0.387	2.248	0.21	0.21	1.35	0.79	template_3	template_3
4	5wq7A1	5wq7	0.343	2.740	0.13	0.11	1.19	0.79	template_4	template_4	GO:0008565	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
5	3ezjG2	3ezj	0.387	2.324	0.20	0.16	0.96	0.78	template_5	template_5
6	2n2uA	2n2u	0.263	2.799	0.06	0.05	1.35	0.77	template_6	template_6
7	4e9jA2	4e9j	0.372	2.272	0.13	0.11	1.14	0.77	template_7	template_7
8	1dq3A3	1dq3	0.321	2.803	0.13	0.12	1.42	0.74	template_8	template_8	GO:0004519,GO:0016788	GO:0016539		1.17.4.1
9	4e9jA3	4e9j	0.358	2.283	0.13	0.11	1.21	0.73	template_9	template_9
10	5ho1A	5ho1	0.197	3.535	0.18	0.18	1.51	0.73	template_10	template_10					ZN	H40 D42 H78

Templates from CEthreader

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	6y2qA1	6y2q	0.540	2.119	0.12	0.12	1.68	0.85	template_1	template_1
2	7bfqB2	7bfq	0.460	2.041	0.07	0.07	1.58	0.67	template_2	template_2
3	3sqgB2	3sqg	0.445	2.708	0.14	0.14	2.67	0.66	template_3	template_3	GO:0050524,GO:0016740	GO:0015948		2.8.4.1	SO4	A29 K88 R89
4	1wqaA4	1wqa	0.431	2.610	0.14	0.14	1.53	0.61	template_4	template_4	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8
5	4b0aA1	4b0a	0.438	2.564	0.12	0.12	2.74	0.59	template_5	template_5	GO:0003677	GO:0006352		2.3.1.48	CA CA	G29 D31 D31 D38 Y39 N92
6	5wq7A5	5wq7	0.409	2.100	0.13	0.11	1.09	0.57	template_6	template_6	GO:0008565	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
7	3vn5A1	3vn5	0.431	2.283	0.18	0.18	1.18	0.52	template_7	template_7	GO:0004523,GO:0003723,GO:0003676,GO:0004519,GO:0016787,GO:0046872,GO:0004518,GO:0000287	GO:0090305,GO:0090502,GO:0016070,GO:0006298,GO:0043137,GO:0006401	GO:0005737,GO:0032299	3.1.26.4
8	5a8rB1	5a8r	0.401	2.792	0.07	0.07	2.33	0.52	template_8	template_8	GO:0050524,GO:0016740	GO:0015948
9	4b0aA2	4b0a	0.387	2.746	0.12	0.12	1.42	0.51	template_9	template_9	GO:0003677	GO:0006352		2.3.1.48	CA	G21 S24
10	5wq8A4	5wq8	0.387	2.123	0.04	0.04	1.11	0.51	template_10	template_10	GO:0008565,GO:0042802	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279

Templates from HHsearch

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	7mj0A	7mj0	0.358	3.823	0.25	0.25	3.54	0.34	template_1	template_1
2	4i5sA	4i5s	0.182	4.048	0.19	0.18	6.67	0.28	template_2	template_2	GO:0004673,GO:0000155,GO:0016772,GO:0005524,GO:0016301,GO:0000166,GO:0016740	GO:0000160,GO:0023014,GO:0018106,GO:0007165,GO:0016310,GO:0006355	GO:0016020,GO:0016021	2.7.13.1
3	3hrgA1	3hrg	0.088	7.381	0.14	0.05	2.44	0.25	template_3	template_3
4	4f67A1	4f67	0.124	4.213	0.18	0.14	1.98	0.25	template_4	template_4
5	3d2rB	3d2r	0.139	4.278	0.15	0.14	6.35	0.25	template_5	template_5	GO:0004672,GO:0004740,GO:0005524,GO:0016301,GO:0000166,GO:0016740	GO:0006468,GO:0005975,GO:0006006,GO:0016310,GO:0006885,GO:0010565,GO:0042593,GO:0042594,GO:0046320,GO:0008286,GO:0010510,GO:0010906,GO:0042304,GO:0045124,GO:0009267,GO:0071398,GO:0072593,GO:2000811	GO:0005739,GO:0005759	2.7.11.2	ADP	N238 R241 A242 D273 V278 L286 Y291 S292 T293 A300 G301 F302 G303 G305 L306 T330
6	3crlB2	3crl	0.161	4.332	0.17	0.16	3.77	0.25	template_6	template_6	GO:0004740,GO:0004672,GO:0005524,GO:0016301,GO:0000166,GO:0016740,GO:0004674,GO:0042803,GO:0044877,GO:0046982	GO:0005975,GO:0006006,GO:0016310,GO:0006111,GO:0006885,GO:0008286,GO:0010510,GO:0010565,GO:0010906,GO:0031670,GO:0042593,GO:0006468,GO:0018105	GO:0005739,GO:0005759,GO:0005967,GO:0045254	2.7.11.2	ANP MG	E72 N76 R79 A80 D111 V116 L124 G136 F137 G138 Y139 G140 L141 P142 E72 N76
7	4rkiA2	4rki	0.226	3.980	0.10	0.09	2.32	0.21	template_7	template_7	GO:0003677,GO:0003887,GO:0008408,GO:0016779,GO:0016740,GO:0005515	GO:0006260,GO:0006271,GO:0071897,GO:0090305	GO:0009360,GO:0005737	2.7.7.7
8	6linA2	6lin	0.146	4.313	0.15	0.14	3.11	0.21	template_8	template_8					EH0	L61 N64 R67 A68 D99 G103 V104 K108 L112 Y117 G119 L122 L138 E142 T146
9	6blkC	6blk	0.161	4.003	0.13	0.12	2.77	0.21	template_9	template_9	GO:0016772	GO:0016310		3.1.3.-	ATP	N57 A58 K60 W61 D86 P89 I91 F104 R105 S106 A109 G114 G116 L117 G118 L119 T147
10	2q8gA2	2q8g	0.139	4.285	0.17	0.16	3.02	0.21	template_10	template_10	GO:0004672,GO:0004740,GO:0005524,GO:0016301,GO:0000166,GO:0016740,GO:0005515	GO:0006468,GO:0005975,GO:0006006,GO:0016310,GO:0010510,GO:0008283,GO:0008631,GO:0010906,GO:0097411	GO:0005739,GO:0005759,GO:0005967,GO:0005634,GO:0005730	2.7.11.2

Templates from MapAlign

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	6y2qA1	6y2q	0.606	1.899	0.04	0.04	1.68	0.97	template_1	template_1
2	1sgoA	1sgo	0.584	2.689	0.04	0.04	2.44	0.97	template_2	template_2	GO:0051018,GO:0034237,GO:0005515,GO:0019901,GO:0004860,GO:0008013	GO:0060828,GO:0090263,GO:0006469,GO:0008631,GO:0030111	GO:0005634,GO:0005737
3	1wqaA4	1wqa	0.620	1.898	0.21	0.19	1.53	0.95	template_3	template_3	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8
4	7bfqB2	7bfq	0.584	1.889	0.11	0.11	1.58	0.87	template_4	template_4
5	4b0aA1	4b0a	0.555	1.992	0.10	0.09	2.74	0.82	template_5	template_5	GO:0003677	GO:0006352		2.3.1.48	CA CA	G29 D31 D31 D38 Y39 N92
6	5a1uG10	5a1u	0.591	2.182	0.05	0.05	2.30	0.76	template_6	template_6	GO:0005198	GO:0006886,GO:0016192,GO:0006891,GO:0006888,GO:0015031	GO:0030117,GO:0030126,GO:0005737,GO:0005794,GO:0005798,GO:0016020,GO:0031410,GO:0005886,GO:0030663,GO:0005793,GO:0000139,GO:0005829,GO:0043231,GO:0030137
7	4b0aA2	4b0a	0.504	2.529	0.09	0.09	1.42	0.66	template_7	template_7	GO:0003677	GO:0006352		2.3.1.48	CA	G21 S24
8	6gykO2	6gyk	0.504	2.410	0.08	0.07	1.42	0.66	template_8	template_8	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0000995,GO:0016251,GO:0001016,GO:0001186,GO:0001179,GO:0001102,GO:0003677,GO:0097718,GO:0005515,GO:0001092,GO:0003682,GO:0008301	GO:0006366,GO:0001188,GO:0006355,GO:0070898,GO:0070893,GO:0042790,GO:0051123	GO:0005667,GO:0005669,GO:0000126,GO:0005634,GO:0005672,GO:0032991,GO:0005654
9	6gykO1	6gyk	0.518	2.045	0.10	0.09	1.74	0.66	template_9	template_9	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0000995,GO:0016251,GO:0001016,GO:0001186,GO:0001179,GO:0001102,GO:0003677,GO:0097718,GO:0005515,GO:0001092,GO:0003682,GO:0008301	GO:0006366,GO:0001188,GO:0006355,GO:0070898,GO:0070893,GO:0042790,GO:0051123	GO:0005667,GO:0005669,GO:0000126,GO:0005634,GO:0005672,GO:0032991,GO:0005654
10	3vn5A1	3vn5	0.569	1.955	0.12	0.11	1.18	0.63	template_10	template_10	GO:0004523,GO:0003723,GO:0003676,GO:0004519,GO:0016787,GO:0046872,GO:0004518,GO:0000287	GO:0090305,GO:0090502,GO:0016070,GO:0006298,GO:0043137,GO:0006401	GO:0005737,GO:0032299	3.1.26.4

Templates from MUSTER

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	5v8wA	5v8w	0.416	2.148	0.18	0.18	1.35	0.67	template_1	template_1
2	2nrvA2	2nrv	0.197	3.461	0.22	0.19	1.11	0.61	template_2	template_2
3	3ezjG2	3ezj	0.358	2.147	0.20	0.16	0.96	0.61	template_3	template_3
4	1x2iA	1x2i	0.168	3.237	0.20	0.19	1.19	0.59	template_4	template_4	GO:0003677	GO:0006281
5	1xu4A1	1xu4	0.226	3.881	0.10	0.09	1.07	0.58	template_5	template_5	GO:0003677,GO:0000166,GO:0003684,GO:0005524,GO:0008094,GO:0042802	GO:0006281,GO:0006310,GO:0006259,GO:0006974
6	6i1xA3	6i1x	0.299	3.248	0.14	0.14	1.28	0.58	template_6	template_6
7	4ys2A	4ys2	0.190	3.617	0.16	0.16	1.25	0.58	template_7	template_7	GO:0008324	GO:0006813			2BA	L17 R18 F22 I27 F28 P40 H41 G42
8	3w5xA	3w5x	0.168	3.584	0.13	0.12	1.40	0.58	template_8	template_8
9	5wq8A4	5wq8	0.372	2.168	0.04	0.04	1.11	0.56	template_9	template_9	GO:0008565,GO:0042802	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
10	3vn5A1	3vn5	0.307	2.653	0.20	0.19	1.18	0.56	template_10	template_10	GO:0004523,GO:0003723,GO:0003676,GO:0004519,GO:0016787,GO:0046872,GO:0004518,GO:0000287	GO:0090305,GO:0090502,GO:0016070,GO:0006298,GO:0043137,GO:0006401	GO:0005737,GO:0032299	3.1.26.4

Templates from MRFsearch

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Ligand	Binding site residues
1	7mj0A	7mj0	0.299	4.051	0.23	0.21	3.54	0.60	template_1	template_1
2	2nxuA	2nxu	0.219	3.771	0.13	0.11	2.35	0.47	template_2	template_2	GO:0003743	GO:0006413,GO:0006412
3	3jc8Qa5	3jc8	0.328	2.997	0.23	0.18	1.12	0.47	template_3	template_3			GO:0009279
4	2ljkA	2ljk	0.248	3.224	0.15	0.14	2.05	0.47	template_4	template_4	GO:0005515	GO:0010269,GO:0043066,GO:0051491,GO:0006915,GO:0030335	GO:0005829,GO:0016020,GO:0005737,GO:0005886,GO:0031235
5	7ofhA	7ofh	0.431	2.454	0.07	0.05	4.05	0.47	template_5	template_5
6	6ybvs	6ybv	0.263	2.658	0.11	0.09	2.42	0.45	template_6	template_6				NUC	S72 S74 K84 K118 R121 Y123
7	5w68A	5w68	0.401	2.198	0.05	0.04	6.14	0.43	template_7	template_7		GO:0009306
8	6ve2A1	6ve2	0.394	2.653	0.12	0.09	1.05	0.42	template_8	template_8
9	5wq7A1	5wq7	0.365	2.955	0.14	0.11	1.19	0.42	template_9	template_9	GO:0008565	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
10	4e9jA3	4e9j	0.380	2.641	0.12	0.09	1.21	0.42	template_10	template_10

Templates from DisCovER

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	5v8wA	5v8w	0.591	1.512	0.20	0.19	1.35	0.87	template_1	template_1
2	7cunI2	7cun	0.438	2.609	0.07	0.07	1.35	0.80	template_2	template_2
3	4dsdA1	4dsd	0.350	3.410	0.09	0.05	1.04	0.70	template_3	template_3
4	1wqaA4	1wqa	0.635	1.905	0.18	0.16	1.53	0.67	template_4	template_4	GO:0016868,GO:0008966,GO:0046872	GO:0005975,GO:0071704		5.4.2.8
5	1vokA1	1vok	0.526	2.135	0.12	0.11	1.58	0.64	template_5	template_5	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0003677,GO:0005515	GO:0006366,GO:0006355,GO:0006352	GO:0005667,GO:0005669,GO:0005634
6	2z8uB2	2z8u	0.453	2.612	0.14	0.12	1.35	0.61	template_6	template_6	GO:0003677,GO:0000978,GO:0008134,GO:0003700,GO:0000979	GO:0006352,GO:0006366,GO:0006355	GO:0005667
7	6gykO2	6gyk	0.460	2.936	0.10	0.09	1.42	0.59	template_7	template_7	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0000995,GO:0016251,GO:0001016,GO:0001186,GO:0001179,GO:0001102,GO:0003677,GO:0097718,GO:0005515,GO:0001092,GO:0003682,GO:0008301	GO:0006366,GO:0001188,GO:0006355,GO:0070898,GO:0070893,GO:0042790,GO:0051123	GO:0005667,GO:0005669,GO:0000126,GO:0005634,GO:0005672,GO:0032991,GO:0005654
8	3vn5A1	3vn5	0.474	2.347	0.16	0.14	1.18	0.59	template_8	template_8	GO:0004523,GO:0003723,GO:0003676,GO:0004519,GO:0016787,GO:0046872,GO:0004518,GO:0000287	GO:0090305,GO:0090502,GO:0016070,GO:0006298,GO:0043137,GO:0006401	GO:0005737,GO:0032299	3.1.26.4
9	7bfqB2	7bfq	0.540	1.801	0.10	0.09	1.58	0.58	template_9	template_9
10	4b0aA2	4b0a	0.474	2.608	0.11	0.11	1.42	0.57	template_10	template_10	GO:0003677	GO:0006352		2.3.1.48	CA	G21 S24

Templates from FFAS3D

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	2hg7A	2hg7	0.255	3.628	0.10	0.09	1.05	0.38	template_1	template_1
2	1oltA2	1olt	0.226	3.513	0.15	0.14	1.42	0.35	template_2	template_2	GO:0004109,GO:0003824,GO:0051536,GO:0051539,GO:0046872,GO:0016491,GO:0051989	GO:0006779,GO:0055114,GO:0006782	GO:0005737	1.3.98.3
3	2ebbA	2ebb	0.175	3.657	0.14	0.12	1.68	0.35	template_3	template_3	GO:0008124,GO:0016829	GO:0006729		4.2.1.96
4	2v6uA	2v6u	0.146	3.775	0.20	0.18	1.81	0.35	template_4	template_4	GO:0008124,GO:0016829	GO:0006729		4.2.1.96
5	3j21k2	3j21	0.292	3.726	0.20	0.16	1.33	0.33	template_5	template_5
6	4ftfA	4ftf	0.248	3.763	0.12	0.11	1.91	0.32	template_6	template_6
7	5wq8A4	5wq8	0.343	2.393	0.05	0.04	1.11	0.31	template_7	template_7	GO:0008565,GO:0042802	GO:0009306,GO:0015628,GO:0015031	GO:0015627,GO:0019867,GO:0016020,GO:0009279
8	1usoB	1uso	0.263	3.210	0.20	0.18	1.37	0.31	template_8	template_8	GO:0008124,GO:0016829	GO:0006729
9	2npbA	2npb	0.182	3.406	0.17	0.16	1.54	0.31	template_9	template_9	GO:0016209,GO:0016491	GO:0098869,GO:0055114,GO:0010269	GO:0005829,GO:0005737,GO:0005886
10	1y30A	1y30	0.226	4.109	0.07	0.07	2.51	0.31	template_10	template_10	GO:0048037,GO:0070967,GO:0016627,GO:0016491,GO:0042803,GO:0010181,GO:0030170,GO:0070402,GO:0071949	GO:0055114,GO:0042816	GO:0005829		FMN	Q28 S30 N31 V32 Q33 S46 R51 A52 K53

Templates from EigenThreader

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number
1	7agvA1	7agv	0.423	3.351	0.06	0.05	1.37	0.78	template_1	template_1
2	3qmfA1	3qmf	0.401	3.015	0.08	0.07	2.33	0.75	template_2	template_2		GO:0046854		3.1.3.25
3	7cunI2	7cun	0.438	2.078	0.16	0.16	1.35	0.73	template_3	template_3
4	5v8wA	5v8w	0.518	1.882	0.18	0.18	1.35	0.73	template_4	template_4
5	7bfqB2	7bfq	0.496	1.983	0.05	0.05	1.58	0.68	template_5	template_5
6	6gykO1	6gyk	0.394	2.882	0.10	0.09	1.74	0.63	template_6	template_6	GO:0000978,GO:0008134,GO:0003700,GO:0000979,GO:0000995,GO:0016251,GO:0001016,GO:0001186,GO:0001179,GO:0001102,GO:0003677,GO:0097718,GO:0005515,GO:0001092,GO:0003682,GO:0008301	GO:0006366,GO:0001188,GO:0006355,GO:0070898,GO:0070893,GO:0042790,GO:0051123	GO:0005667,GO:0005669,GO:0000126,GO:0005634,GO:0005672,GO:0032991,GO:0005654
7	5lhxA	5lhx	0.380	2.912	0.08	0.07	1.53	0.63	template_7	template_7	GO:0004674	GO:0006468,GO:0007099	GO:0005814	2.7.11.21
8	2f7lA3	2f7l	0.453	2.132	0.21	0.21	1.53	0.62	template_8	template_8	GO:0016868,GO:0000287,GO:0008966,GO:0016853,GO:0046872	GO:0005975,GO:0071704		5.4.2.2,5.4.2.8
9	6ewjA	6ewj	0.234	3.919	0.04	0.04	7.00	0.62	template_9	template_9	GO:0003824
10	2iy0A	2iy0	0.387	3.138	0.04	0.04	3.96	0.62	template_10	template_10	GO:0008234	GO:0006508		3.4.22.-

Templates from HHpred

Rank	PDB Hit	RCSB Link	CMO	MAE	ID1	ID2	Cov	Norm. Zscore	Download PDB	Download FASTA	Gene_Ontology_(GO)_term (Molecular_Function)	Gene_Ontology_(GO)_term (Biological_Process)	Gene_Ontology_(GO)_term (Cellular_Componenet)	Enzyme_Commission (EC)_number	Ligand	Binding site residues
1	7mj0A	7mj0	0.358	3.823	0.25	0.25	3.54	0.35	template_1	template_1

[Click result.zip to download all results on this page]

References:
1.	W Zheng, Q Wuyun, X Zhou, Y Li, P Freddolino, Y Zhang. LOMETS3: Integrating deep-learning and profile-alignment for advanced protein template recognition and function annotation. in preparation, (2021)
2.	W Zheng, C Zhang, Q Wuyun, R Pearce, Y Li, Y Zhang. LOMETS2: improved meta-threading server for fold-recognition and structure-based function annotation for distant-homology proteins. Nucleic Acids Research, 47: W429-W436 (2019).
3.	S Wu, Y Zhang. LOMETS: A local meta-threading-server for protein structure prediction. Nucleic Acids Research, 35: 3375-3382 (2007).